GRK2 (NM_001619) Human Mass Spec Standard

CAT#: PH310327

ADRBK1 MS Standard C13 and N15-labeled recombinant protein (NP_001610)



  View other "GRK2" proteins (3)

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CNY 19,520.00


货期*
4周

规格
    • 10 ug

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Specifications

Product Data
Description ADRBK1 MS Standard C13 and N15-labeled recombinant protein (NP_001610)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC210327
Predicted MW 79.4 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_001610
RefSeq Size 3603
RefSeq ORF 2076
Synonyms ADRBK1; BARK1; BETA-ARK1
Locus ID 156
Cytogenetics 11q13.2
Summary This gene encodes a member of the G protein-coupled receptor kinase family of proteins. The encoded protein phosphorylates the beta-adrenergic receptor as well as a wide range of other substrates including non-GPCR cell surface receptors, and cytoskeletal, mitochondrial, and transcription factor proteins. Data from rodent models supports a role for this gene in embryonic development, heart function and metabolism. Elevated expression of this gene has been observed in human patients with heart failure and Alzheimer's disease. [provided by RefSeq, Sep 2017]
Protein Families Druggable Genome, Protein Kinase
Protein Pathways Chemokine signaling pathway, Endocytosis
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