DHLAG (CD74) (NM_001025159) Human Mass Spec Standard

CAT#: PH312964

CD74 MS Standard C13 and N15-labeled recombinant protein (NP_001020330)



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CNY 19,520.00


货期*
4周

规格
    • 10 ug

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Specifications

Product Data
Description CD74 MS Standard C13 and N15-labeled recombinant protein (NP_001020330)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC212964
Predicted MW 33.3 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_001020330
RefSeq Size 1519
RefSeq ORF 888
Synonyms DHLAG; HLADG; Ia-GAMMA; II; p33
Locus ID 972
Cytogenetics 5q33.1
Summary The protein encoded by this gene associates with class II major histocompatibility complex (MHC) and is an important chaperone that regulates antigen presentation for immune response. It also serves as cell surface receptor for the cytokine macrophage migration inhibitory factor (MIF) which, when bound to the encoded protein, initiates survival pathways and cell proliferation. This protein also interacts with amyloid precursor protein (APP) and suppresses the production of amyloid beta (Abeta). Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2011]
Protein Families Druggable Genome, Transmembrane
Protein Pathways Antigen processing and presentation
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