Endonuclease V (ENDOV) (NM_173627) Human Mass Spec Standard

CAT#: PH315740

FLJ35220 MS Standard C13 and N15-labeled recombinant protein (NP_775898)



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CNY 19,520.00


货期*
4周

规格
    • 10 ug

Cited in 1 publication.

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经常一起买 (1)
Transient overexpression lysate of hypothetical protein FLJ35220 (FLJ35220), transcript variant 1
    • 100 ug

CNY 3,080.00

Specifications

Product Data
Description FLJ35220 MS Standard C13 and N15-labeled recombinant protein (NP_775898)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC215740
Predicted MW 30.6 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_775898
RefSeq Size 2858
RefSeq ORF 846
Locus ID 284131
Cytogenetics 17q25.3
Summary Endoribonuclease that specifically cleaves inosine-containing RNAs: cleaves RNA at the second phosphodiester bond 3' to inosine. Has strong preference for single-stranded RNAs (ssRNAs) toward double-stranded RNAs (dsRNAs). Cleaves mRNAs and tRNAs containing inosine. Also able to cleave structure-specific dsRNA substrates containing the specific sites 5'-IIUI-3' and 5'-UIUU-3'. Inosine is present in a number of RNAs following editing; the function of inosine-specific endoribonuclease is still unclear: it could either play a regulatory role in edited RNAs, or be involved in antiviral response by removing the hyperedited long viral dsRNA genome that has undergone A-to-I editing. Binds branched DNA structures.[UniProtKB/Swiss-Prot Function]
Protein Families Druggable Genome
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Citations (1)

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