CARD9 (NM_052813) Human Mass Spec Standard

CAT#: PH315899

CARD9 MS Standard C13 and N15-labeled recombinant protein (NP_434700)



  View other "CARD9" proteins (7)

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CNY 19,520.00


货期*
4周

规格
    • 10 ug

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Specifications

Product Data
Description CARD9 MS Standard C13 and N15-labeled recombinant protein (NP_434700)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC215899
Predicted MW 62.1 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_434700
RefSeq Size 2136
RefSeq ORF 1608
Synonyms CANDF2; hCARD9
Locus ID 64170
Cytogenetics 9q34.3
Summary The protein encoded by this gene is a member of the CARD protein family, which is defined by the presence of a characteristic caspase-associated recruitment domain (CARD). CARD is a protein interaction domain known to participate in activation or suppression of CARD containing members of the caspase family, and thus plays an important regulatory role in cell apoptosis. This protein was identified by its selective association with the CARD domain of BCL10, a postive regulator of apoptosis and NF-kappaB activation, and is thought to function as a molecular scaffold for the assembly of a BCL10 signaling complex that activates NF-kappaB. Several alternatively spliced transcript variants have been observed, but their full-length nature is not clearly defined. [provided by RefSeq, Jul 2008]
Protein Families Druggable Genome
Protein Pathways NOD-like receptor signaling pathway
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