ACSL6 (NM_015256) Human Mass Spec Standard

Specifications

Product Data
Description	ACSL6 MS Standard C13 and N15-labeled recombinant protein (NP_056071)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC216974
Predicted MW	80.3 kDa
Protein Sequence	Sequence Link (showhide) RC216974
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_056071
RefSeq Size	3047
RefSeq ORF	2166
Synonyms	ACS2; FACL6; LACS2; LACS5; LACS 6
Locus ID	23305
Cytogenetics	5q31.1
Summary	The protein encoded by this gene catalyzes the formation of acyl-CoA from fatty acids, ATP, and CoA, using magnesium as a cofactor. The encoded protein plays a major role in fatty acid metabolism in the brain. Translocations with the ETV6 gene are causes of myelodysplastic syndrome with basophilia, acute myelogenous leukemia with eosinophilia, and acute eosinophilic leukemia. Several transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Apr 2011]
Protein Families	Druggable Genome, Transmembrane
Protein Pathways	Adipocytokine signaling pathway, Fatty acid metabolism, Metabolic pathways, PPAR signaling pathway

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