NMDAR1 (GRIN1) (NM_000832) Human Mass Spec Standard

CAT#: PH319368

GRIN1 MS Standard C13 and N15-labeled recombinant protein (NP_000823)



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CNY 19,520.00


货期*
4周

规格
    • 10 ug

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Specifications

Product Data
Description GRIN1 MS Standard C13 and N15-labeled recombinant protein (NP_000823)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC219368
Predicted MW 99.31 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_000823
RefSeq Size 3902
RefSeq ORF 2655
Synonyms GluN1; MRD8; NDHMSD; NDHMSR; NMD-R1; NMDA1; NMDAR1; NR1
Locus ID 2902
Cytogenetics 9q34.3
Summary The protein encoded by this gene is a critical subunit of N-methyl-D-aspartate receptors, members of the glutamate receptor channel superfamily which are heteromeric protein complexes with multiple subunits arranged to form a ligand-gated ion channel. These subunits play a key role in the plasticity of synapses, which is believed to underlie memory and learning. Cell-specific factors are thought to control expression of different isoforms, possibly contributing to the functional diversity of the subunits. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2008]
Protein Families Druggable Genome, Ion Channels: Glutamate Receptors, Transmembrane
Protein Pathways Alzheimer's disease, Amyotrophic lateral sclerosis (ALS), Calcium signaling pathway, Huntington's disease, Long-term potentiation, Neuroactive ligand-receptor interaction
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