CTPS2 (NM_175859) Human Mass Spec Standard

CAT#: PH320566

CTPS2 MS Standard C13 and N15-labeled recombinant protein (NP_787055)



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CNY 19,520.00


货期*
4周

规格
    • 10 ug

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Specifications

Product Data
Description CTPS2 MS Standard C13 and N15-labeled recombinant protein (NP_787055)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC220566
Predicted MW 65.7 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_787055
RefSeq Size 3973
RefSeq ORF 1758
Synonyms GATD5B
Locus ID 56474
Cytogenetics Xp22.2
Summary The protein encoded by this gene catalyzes the formation of CTP from UTP with the concomitant deamination of glutamine to glutamate. This protein is the rate-limiting enzyme in the synthesis of cytosine nucleotides, which play an important role in various metabolic processes and provide the precursors necessary for the synthesis of RNA and DNA. Cancer cells that exhibit increased cell proliferation also exhibit an increased activity of this encoded protein. Thus, this protein is an attractive target for selective chemotherapy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]
Protein Pathways Metabolic pathways, Pyrimidine metabolism
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