Junctional Adhesion Molecule 1 (F11R) (NM_016946) Human Mass Spec Standard

CAT#: PH321478

F11R MS Standard C13 and N15-labeled recombinant protein (NP_058642)



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CNY 19,520.00


货期*
4周

规格
    • 10 ug

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Specifications

Product Data
Description F11R MS Standard C13 and N15-labeled recombinant protein (NP_058642)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC221478
Predicted MW 32.58 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_058642
RefSeq Size 3660
RefSeq ORF 897
Synonyms CD321; JAM; JAM1; JAMA; JCAM; KAT; PAM-1
Locus ID 50848
Cytogenetics 1q23.3
Summary Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. The protein encoded by this immunoglobulin superfamily gene member is an important regulator of tight junction assembly in epithelia. In addition, the encoded protein can act as (1) a receptor for reovirus, (2) a ligand for the integrin LFA1, involved in leukocyte transmigration, and (3) a platelet receptor. Multiple 5' alternatively spliced variants, encoding the same protein, have been identified but their biological validity has not been established. [provided by RefSeq, Jul 2008]
Protein Families Druggable Genome, Transmembrane
Protein Pathways Cell adhesion molecules (CAMs), Epithelial cell signaling in Helicobacter pylori infection, Leukocyte transendothelial migration, Tight junction
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