CD10 (MME) (NM_007289) Human Mass Spec Standard

CAT#: PH323116

MME MS Standard C13 and N15-labeled recombinant protein (NP_009220)



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CNY 19,520.00


货期*
4周

规格
    • 10 ug

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Specifications

Product Data
Description MME MS Standard C13 and N15-labeled recombinant protein (NP_009220)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC223116
Predicted MW 85.3 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_009220
RefSeq Size 5725
RefSeq ORF 2250
Synonyms CALLA; CD10; CMT2T; NEP; SCA43; SFE
Locus ID 4311
Cytogenetics 3q25.2
Summary The protein encoded by this gene is a type II transmembrane glycoprotein and a common acute lymphocytic leukemia antigen that is an important cell surface marker in the diagnosis of human acute lymphocytic leukemia (ALL). The encoded protein is present on leukemic cells of pre-B phenotype, which represent 85% of cases of ALL. This protein is not restricted to leukemic cells, however, and is found on a variety of normal tissues. The protein is a neutral endopeptidase that cleaves peptides at the amino side of hydrophobic residues and inactivates several peptide hormones including glucagon, enkephalins, substance P, neurotensin, oxytocin, and bradykinin. [provided by RefSeq, Aug 2017]
Protein Families Druggable Genome, Protease, Transmembrane
Protein Pathways Alzheimer's disease, Hematopoietic cell lineage, Renin-angiotensin system
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