RNASEH2B (NM_001142279) Human Mass Spec Standard

CAT#: PH326833

RNASEH2B MS Standard C13 and N15-labeled recombinant protein (NP_001135751)



  View other "RNASEH2B" proteins (5)

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CNY 19,520.00


货期*
4周

规格
    • 10 ug

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Specifications

Product Data
Description RNASEH2B MS Standard C13 and N15-labeled recombinant protein (NP_001135751)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC226833
Predicted MW 28.8 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_001135751
RefSeq ORF 771
Synonyms AGS2; DLEU8
Locus ID 79621
Cytogenetics 13q14.3
Summary RNase H2 is composed of a single catalytic subunit (A) and two non-catalytic subunits (B and C) and specifically degrades the RNA of RNA:DNA hybrids. The protein encoded by this gene is the non-catalytic B subunit of RNase H2, which is thought to play a role in DNA replication. Multiple transcript variants encoding different isoforms have been found for this gene. Defects in this gene are a cause of Aicardi-Goutieres syndrome type 2 (AGS2). [provided by RefSeq, Nov 2008]
Protein Pathways DNA replication
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