Pleiotrophin / PTN Human Protein

Specifications

Product Data
Species	Human
Expression Host	E. coli
Expression cDNA Clone or AA Sequence	Protein Sequence (showhide) MKHHHHHHHM LVPRGSGKKE KPEKKVKKSD CGEWQWSVCV PTSGDCGLGT REGTRTGAEC KQTMKTQRCK IPCNWKKQFG AECKYQFQAW GECDLNTALK TRTGSLKRAL HNAECQKTVT ISKPCGKLTK PKPQAESKKK KKEGKKQEKM LD
Predicted MW	17.3 kDa
Concentration	lot specific
Purity	>95% pure by SDS PAGE
Buffer	Presentation State: Purified State: Lyophilized (0.4µm filtered) purified protein Buffer System: 0.1M Phosphate buffer, 0.1M NaCl, pH 7.2
Preparation	Lyophilized (0.4µm filtered) purified protein
Applications	ELISA. Western Blot.
Protein Description	Total 152 AA. MW: 17.3 kDa. N-Terminal His-tag and Thrombin cleavage site 16 AA (highlighted).
Note	Product is not sterile! Please filter the product by an appropriate sterile filter before using it in the cell culture.
Storage	Store lyophilized (preferably in a desiccator) at -20°C and in aliquots at -80°C. Reconstituted antibody can be stored at 4°C for a limited period of time; it does not show decline in activity after two weeks at 4°C. Avoid repeated freezing and thawing.
Stability	Shelf life: one year from despatch.
Reference Data
RefSeq	NP_001308315
Locus ID	5764
UniProt ID	P21246, A0A024R778
Cytogenetics	7q33
Synonyms	HARP; HB-GAM; HBBM; HBGF-8; HBGF8; HBNF; HBNF-1; NEGF1; OSF-1
Summary	The protein encoded by this gene is a secreted heparin-binding growth factor. The protein has significant roles in cell growth and survival, cell migration, angiogenesis and tumorigenesis. Alternative splicing and the use of alternative promoters results in multiple transcript variants. [provided by RefSeq, Oct 2016]
Protein Families	Druggable Genome, Phosphatase, Secreted Protein, Transmembrane

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