RANTES (CCL5) (NM_002985) Human Recombinant Protein

CAT#: TP720050M

Recombinant protein of human chemokine (C-C motif) ligand 5 (CCL5)

Size: 10 ug 50 ug 500 ug 1 mg



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CNY 7,220.00


货期*
2周

规格
    • 50 ug

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经常一起买 (1)
CCL5 mouse monoclonal antibody, clone OTI2A7 (formerly 2A7)
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Specifications

Product Data
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence
Tag Tag Free
Predicted MW 7.8 kDa
Concentration lot specific
Purity >95% as determined by SDS-PAGE and Coomassie blue staining
Buffer Lyophilized from a 0.2 um filtered solution of 20mM PB, 150mM NaCl, pH 7.4.
Storage Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Stability Stable for at least 6 months from date of receipt under proper storage and handling conditions.
Endotoxin < 0.1 EU per µg protein as determined by LAL test
Reference Data
RefSeq NP_002976
Locus ID 6352
UniProt ID P13501, D0EI67
Cytogenetics 17q12
Synonyms D17S136E; eoCP; RANTES; SCYA5; SIS-delta; SISd; TCP228
Summary This gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of the N-terminal cysteine residues of the mature peptide. This chemokine, a member of the CC subfamily, functions as a chemoattractant for blood monocytes, memory T helper cells and eosinophils. It causes the release of histamine from basophils and activates eosinophils. This cytokine is one of the major HIV-suppressive factors produced by CD8+ cells. It functions as one of the natural ligands for the chemokine receptor chemokine (C-C motif) receptor 5 (CCR5), and it suppresses in vitro replication of the R5 strains of HIV-1, which use CCR5 as a coreceptor. Alternative splicing results in multiple transcript variants that encode different isoforms. [provided by RefSeq, Jul 2013]
Protein Families Druggable Genome, Secreted Protein, Transmembrane
Protein Pathways Chemokine signaling pathway, Cytokine-cytokine receptor interaction, Cytosolic DNA-sensing pathway, Epithelial cell signaling in Helicobacter pylori infection, NOD-like receptor signaling pathway, Prion diseases, Toll-like receptor signaling pathway
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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