Rhesus Recombinant Protein

Specifications

Product Data
Species	Rhesus
Protein Source	Human
Expression cDNA Clone or AA Sequence	Protein Sequence (showhide) Gln18-Val739
Tag	C-Fc
Buffer	Supplied as a 0.2 um filtered solution of PBS,pH7.4.
Note	Recombinant Rhesus macaque Angiotensin-Converting Enzyme 2 is produced by our Mammalian expression system and the target gene encoding Gln18-Val739 is expressed with a Fc tag at the C-terminus.
Stability	12 months from date of despatch
Reference Data
Summary	Angiotensin-Converting Enzyme 2 (ACE-2) is an integral membrane protein and a zinc metalloprotease of the ACE family, the ACE family includes somatic and germinal ACE. ACE-2 cleaves angiotensins I and II as a carboxypeptidase, ACE-2 converts angiotensin I to angiotensin 1-9, and angiotensin II to angiotensin 1-7. ACE-2 is also able to hydrolyze apelin-13 and dynorphin-13 with high efficiency. ACE-2 can be high expressed in testis, kidney and heart, in colon, small intestine and ovary at moderate levels. Captopril and lisinopril as the classical ACE inhibitor don’t inhibit ACE-2 activity. ACE-2 may play an important role in regulating the heart function.

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.