Rhesus Recombinant Protein

Specifications

Product Data
Species	Rhesus
Protein Source	Human
Expression cDNA Clone or AA Sequence	Protein Sequence (showhide) Ala19-Val367
Tag	N-His
Buffer	Lyophilized from a 0.2 um filtered solution of PBS, pH 7.4.
Note	Recombinant Macaca mulatta alpha-2-HS-Glycoprotein is produced by our Mammalian expression system and the target gene encoding Ala19-Val367 is expressed with a 10His tag at the C-terminus.
Stability	12 months from date of despatch
Reference Data
Summary	Alpha-2-HS-glycoprotein (AHSG) is a glycoprotein that is composed of two subunits, the A and B chains, belongs to the Cystatin family of proteases inhibitors. It is highly expressed in embryonic cells and adult hepatocytes, and is expressed to a lesser extent in monocytes/macrophages. AHSG is an important circulating inhibitor of calcification in vivo, and is downregulated during the acute-phase response. It is involved in several functions, such as endocytosis, brain development and the formation of bone tissue. In addition, AHSG may influence the resolution of inflammation by modulating the phagocytosis of apoptotic cells by macrophages. ASHG blocks TGF-beta-dependent signaling in osteoblastic cells.

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