VEGFB Human Recombinant Protein
CAT#: TP727721
Recombinant Human Vascular Eendothelial Growth Factor B/VEGFB (N-Fc)
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CNY 2,380.00
货期*
2周
规格
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经常一起买 (1)
VEGFB mouse monoclonal antibody, clone OTI1H9 (formerly 1H9)
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Specifications
Product Data | |
Species | Human |
Protein Source | Human |
Expression cDNA Clone or AA Sequence |
Pro22-Ala207
|
Tag | N-Fc |
Buffer | Lyophilized from a 0.2 um filtered solution of PBS, pH 7.4. |
Note | Recombinant Human Vascular Endothelial Growth Factor B is produced by our Mammalian expression system and the target gene encoding Pro22-Ala207 is expressed with a Fc tag at the N-terminus. |
Stability | 12 months from date of despatch |
Reference Data | |
Locus ID | 7423 |
UniProt ID | P49765 |
Summary | VEGFB, as known as VRF, is a member of the VEGF family of growth factors that share structural and functional similarity. By alternative splicing, two isoforms of mature VEGF-B containing 167 or 186 amino acid (aa) residues exist. VEGF-B is expressed in most tissues, especially in heart, skeletal muscle and pancreas. The two VEGF-B isoforms have identical amino-terminal cysteine-knot VEGF homology domains but the carboxyl end of VEGF-B167 differs from that of VEGF-B186 by the presence of a highly basic cysteine-rich heparin binding domain. VEGF-B167 and a proteolytically processed form of VEGF-B186 also bind neuropilin-1, a type I transmembrane receptor for semaphorins/collapsins, ligands involved in neuron guidance. |
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