PVR Rhesus Recombinant Protein

Specifications

Product Data
Species	Rhesus
Protein Source	Human
Expression cDNA Clone or AA Sequence	Protein Sequence (showhide) Met 1-Asn 343
Tag	C-6His
Buffer	Lyophilized from a 0.2 um filtered solution of PBS, pH 7.4.
Note	Recombinant Rhesus macaque Poliovirus Receptor Isoform Alpha is produced by our Mammalian expression system and the target gene encoding Met 1-Asn 343 is expressed with a 6His tag at the C-terminus.
Stability	12 months from date of despatch
Reference Data
Locus ID	712851
Summary	Poliovirus Receptor (PVR) is a 70 kDa type I transmembrane single-span glycoprotein that belongs to the nectin-like (Necl) family and was originally identified based on its ability to mediate the cell attachment and entry of poliovirus (PV), an etiologic agent of the central nervous system disease poliomyelitis. PVR contains three Ig-like extracellular domains, a transmembrane segment, and a cytoplasmic tail. The normal cellular function of PVR maybe the involvement of intercellular adhension between epithelial cells. Alternate splicing of the PVR mRNA yields four different isoforms (α, β, γ, and δ) with identical extracellular domains.

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