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Species
Target Symbol
- ALPHA DYSTROGLYCAN (13)
- DISC1 (12)
- IGHG1 (10)
- MITF (10)
- VEGFA (10)
- BHLHB9 (8)
- FGFR1 (8)
- IGLL1 (8)
- NRG1 (8)
- OPA1 (8)
- UBE2D3 (8)
- BIN1 (7)
- CAMK2G (7)
- HLA (7)
- MAX (7)
- NAT1 (7)
- RAD17 (7)
- SNRPN (7)
- TAU (7)
- ZBTB20 (7)
- ACRV1 (6)
- APOL3 (6)
- ARMCX5 (6)
- CACNA1C (6)
- CAMK2D (6)
- CAMKK2 (6)
- CPNE1 (6)
- DYSTROBREVIN ALPHA (6)
- HNF 4 ALPHA (6)
- MST1 (6)
- NDUFC1 (6)
- P38 (6)
- PTGER3 (6)
- RANTES (6)
- RPS6KA3 (6)
- SSH3BP1 (6)
- TJAP1 (6)
- ZDHHC16 (6)
- 5HT4 RECEPTOR (5)
- BDNF (5)
- BLCAP (5)
- CAMK2B (5)
- CASPASE 8 (5)
- CATHEPSIN B (5)
- CD46 (5)
- CD89 (5)
- CHREBP (5)
- CKII ALPHA (5)
- GABPB2 (5)
- GSK3 BETA (5)
- HGF (5)
- IL1RAP (5)
- IRF5 (5)
- JNK1 (5)
- LIM KINASE 2 (5)
- MCFD2 (5)
- MYOSIN LIGHT CHAIN KINASE (5)
- PYK2 (5)
- RIBONUCLEASE INHIBITOR (5)
- SH2B1 (5)
- TCF12 (5)
- TRKC (5)
- UBE2I (5)
- ACAT1 (4)
- ALKALINE PHOSPHATASE (4)
- ALPHA 1A ADRENERGIC RECEPTOR (4)
- AMCASE (4)
- ANGIOTENSIN II TYPE 1 RECEPTOR (4)
- APBB3 (4)
- ASIALOGLYCOPROTEIN RECEPTOR 2 (4)
- ASPARTATE BETA HYDROXYLASE (4)
- ATG16L1 (4)
- ATPASE INHIBITORY FACTOR 1 (4)
- BIM (4)
- CALDESMON (4)
- CALPASTATIN (4)
- CAMK2A (4)
- CANNABINOID RECEPTOR I (4)
- CARD8 (4)
- CAVEOLIN 1 (4)
- CD10 (4)
- CD147 (4)
- CD200R (4)
- CD44 (4)
- CDK2 (4)
- CDK4 (4)
- COPS7A (4)
- CREM (4)
- DACH1 (4)
- DDR2 (4)
- DNAJC14 (4)
- DPP8 (4)
- DYRK2 (4)
- ERG (4)
- FGF8 (4)
- FGFR2 (4)
- FGFR4 (4)
- FOXP2 (4)
- FXYD6 (4)
- GALECTIN 8 (4)
Tags
Mutants
Families
- Druggable Genome (7409)
- Transmembrane (4287)
- Transcription Factors (1896)
- Secreted Protein (1227)
- Protein Kinase (941)
- Protease (504)
- ES Cell Differentiation/IPS (442)
- GPCR (364)
- Stem cell - Pluripotency (338)
- Phosphatase (217)
- Ion Channels: Other (137)
- Adult stem cells (104)
- Embryonic stem cells (83)
- Ion Channels: Potassium (81)
- Nuclear Hormone Receptor (81)
- Cancer stem cells (51)
- P450 (48)
- Induced pluripotent stem cells (46)
- Ion Channels: Cys-loop Receptors (46)
- Ion Channels: Transient receptor potential (32)
- Ion Channels: Glutamate Receptors (24)
- Stem cell relevant signaling - JAK/STAT signaling pathway (24)
- Stem cell relevant signaling - Wnt Signaling pathway (23)
- Ion Channels: Sodium (22)
- Stem cell relevant signaling - DSL/Notch pathway (22)
- Stem cell relevant signaling - TGFb/BMP signaling pathway (22)
- Ion Channels: Calcium (16)
- Ion Channels: ATP Receptors (9)
- Ion Channels: Cyclic nucleotide gated (6)
Pathways
- Metabolic pathways (1065)
- Pathways in cancer (499)
- MAPK signaling pathway (415)
- Neuroactive ligand-receptor interaction (320)
- Cytokine-cytokine receptor interaction (310)
- Regulation of actin cytoskeleton (278)
- Focal adhesion (273)
- Neurotrophin signaling pathway (242)
- Calcium signaling pathway (234)
- Chemokine signaling pathway (233)
- Wnt signaling pathway (228)
- Endocytosis (227)
- Alzheimer's disease (196)
- Huntington's disease (195)
- Insulin signaling pathway (187)
- Ubiquitin mediated proteolysis (177)
- Axon guidance (174)
- Jak-STAT signaling pathway (173)
- ErbB signaling pathway (169)
- Cell cycle (167)
- Cell adhesion molecules (CAMs) (166)
- Natural killer cell mediated cytotoxicity (165)
- Tight junction (165)
- Progesterone-mediated oocyte maturation (163)
- T cell receptor signaling pathway (163)
- Oocyte meiosis (160)
- GnRH signaling pathway (156)
- Melanogenesis (155)
- Toll-like receptor signaling pathway (151)
- Purine metabolism (150)
- Vascular smooth muscle contraction (149)
- Leukocyte transendothelial migration (146)
- Prostate cancer (142)
- Fc gamma R-mediated phagocytosis (134)
- Parkinson's disease (132)
- Pancreatic cancer (131)
- Apoptosis (130)
- Colorectal cancer (130)
- Lysosome (127)
- Melanoma (127)
- Oxidative phosphorylation (127)
- Spliceosome (124)
- VEGF signaling pathway (121)
- Long-term potentiation (120)
- Fc epsilon RI signaling pathway (117)
- Hematopoietic cell lineage (117)
- Small cell lung cancer (117)
- Chronic myeloid leukemia (115)
- Glioma (114)
- Renal cell carcinoma (114)
- Adherens junction (112)
- Dilated cardiomyopathy (111)
- Gap junction (109)
- B cell receptor signaling pathway (106)
- Viral myocarditis (106)
- Pyrimidine metabolism (105)
- Ribosome (105)
- p53 signaling pathway (104)
- NOD-like receptor signaling pathway (103)
- TGF-beta signaling pathway (103)
- Hypertrophic cardiomyopathy (HCM) (102)
- Epithelial cell signaling in Helicobacter pylori infection (101)
- Antigen processing and presentation (99)
- Acute myeloid leukemia (98)
- Adipocytokine signaling pathway (98)
- ECM-receptor interaction (95)
- RIG-I-like receptor signaling pathway (94)
- Systemic lupus erythematosus (94)
- Arrhythmogenic right ventricular cardiomyopathy (ARVC) (92)
- Long-term depression (92)
- Non-small cell lung cancer (92)
- mTOR signaling pathway (92)
- Complement and coagulation cascades (85)
- PPAR signaling pathway (85)
- Endometrial cancer (83)
- Amyotrophic lateral sclerosis (ALS) (82)
- Bladder cancer (78)
- Hedgehog signaling pathway (78)
- Type II diabetes mellitus (77)
- Cardiac muscle contraction (72)
- Olfactory transduction (72)
- Phosphatidylinositol signaling system (72)
- Basal cell carcinoma (68)
- Glycolysis / Gluconeogenesis (68)
- Drug metabolism - cytochrome P450 (67)
- Glycerophospholipid metabolism (64)
- Vibrio cholerae infection (63)
- Metabolism of xenobiotics by cytochrome P450 (62)
- Pathogenic Escherichia coli infection (62)
- Cytosolic DNA-sensing pathway (61)
- Type I diabetes mellitus (57)
- Graft-versus-host disease (56)
- Autoimmune thyroid disease (55)
- Arachidonic acid metabolism (54)
- Valine (54)
- Notch signaling pathway (52)
- Retinol metabolism (52)
- Prion diseases (51)
- Inositol phosphate metabolism (50)
- Lysine degradation (50)
- Allograft rejection (49)
- Drug metabolism - other enzymes (49)
- Primary immunodeficiency (49)
- Glutathione metabolism (48)
- Glycerolipid metabolism (48)
- Starch and sucrose metabolism (47)
- Proteasome (46)
- Sphingolipid metabolism (46)
- Nucleotide excision repair (45)
- Pyruvate metabolism (44)
- Amino sugar and nucleotide sugar metabolism (43)
- Arginine and proline metabolism (43)
- Fatty acid metabolism (43)
- SNARE interactions in vesicular transport (43)
- Taste transduction (43)
- leucine and isoleucine degradation (43)
- N-Glycan biosynthesis (42)
- Tyrosine metabolism (42)
- ABC transporters (41)
- Androgen and estrogen metabolism (41)
- RNA degradation (41)
- Thyroid cancer (40)
- Asthma (39)
- Cysteine and methionine metabolism (39)
- Propanoate metabolism (39)
- Tryptophan metabolism (39)
- Fructose and mannose metabolism (38)
- Maturity onset diabetes of the young (37)
- Alanine (36)
- DNA replication (36)
- aspartate and glutamate metabolism (36)
- Ether lipid metabolism (35)
- Aminoacyl-tRNA biosynthesis (34)
- Base excision repair (33)
- Butanoate metabolism (33)
- Regulation of autophagy (32)
- Glycine (31)
- Porphyrin and chlorophyll metabolism (31)
- serine and threonine metabolism (31)
- Basal transcription factors (30)
- Citrate cycle (TCA cycle) (29)
- Galactose metabolism (28)
- Glycosylphosphatidylinositol(GPI)-anchor biosynthesis (28)
- Homologous recombination (28)
- Pentose phosphate pathway (28)
- O-Glycan biosynthesis (27)
- Glycosaminoglycan degradation (26)
- Nicotinate and nicotinamide metabolism (26)
- RNA polymerase (26)
- Linoleic acid metabolism (25)
- Mismatch repair (25)
- Dorso-ventral axis formation (24)
- Histidine metabolism (24)
- beta-Alanine metabolism (24)
- Biosynthesis of unsaturated fatty acids (23)
- Selenoamino acid metabolism (23)
- Glycosphingolipid biosynthesis - lacto and neolacto series (22)
- Phenylalanine metabolism (22)
- Riboflavin metabolism (22)
- Nitrogen metabolism (21)
- Renin-angiotensin system (21)
- Heparan sulfate biosynthesis (20)
- Ascorbate and aldarate metabolism (19)
- Primary bile acid biosynthesis (19)
- Other glycan degradation (18)
- alpha-Linolenic acid metabolism (18)
- Chondroitin sulfate biosynthesis (17)
- Sulfur metabolism (17)
- Keratan sulfate biosynthesis (16)
- Pentose and glucuronate interconversions (16)
- Terpenoid backbone biosynthesis (16)
- Non-homologous end-joining (15)
- Glycosphingolipid biosynthesis - ganglio series (14)
- Glycosphingolipid biosynthesis - globo series (14)
- Pantothenate and CoA biosynthesis (14)
- Steroid biosynthesis (14)
- Circadian rhythm - mammal (13)
- Glyoxylate and dicarboxylate metabolism (13)
- One carbon pool by folate (13)
- leucine and isoleucine biosynthesis (13)
- C21-Steroid hormone metabolism (12)
- Caffeine metabolism (12)
- Limonene and pinene degradation (12)
- Protein export (12)
- Taurine and hypotaurine metabolism (12)
- Folate biosynthesis (9)
- Synthesis and degradation of ketone bodies (9)
- Thiamine metabolism (9)
- Cyanoamino acid metabolism (8)
- Fatty acid biosynthesis (8)
- Methane metabolism (6)
- Phenylalanine (6)
- Ubiquinone and other terpenoid-quinone biosynthesis (6)
- Vitamin B6 metabolism (6)
- tyrosine and tryptophan biosynthesis (6)
- Fatty acid elongation in mitochondria (5)
- D-Glutamine and D-glutamate metabolism (4)
- Lipoic acid metabolism (3)
- O-Mannosyl glycan biosynthesis (3)
- Biotin metabolism (2)
- Lysine biosynthesis (2)
- D-Arginine and D-ornithine metabolism (1)
