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Species
Target Symbol
- BRCA1 (398)
- BTK (295)
- BRCA2 (278)
- GLUCOKINASE (252)
- TUBERIN (245)
- MENIN (241)
- MLH1 (236)
- MSH2 (216)
- RET (187)
- NOTCH3 (160)
- P53 (106)
- NF2 (105)
- MSH6 (87)
- LKB1 (83)
- FGFR1 (74)
- WILMS TUMOR PROTEIN (72)
- PI 3 KINASE CATALYTIC SUBUNIT ALPHA (69)
- FH (61)
- G PROTEIN ALPHA S (58)
- EGFR (53)
- BETA CATENIN (49)
- PTEN (48)
- B RAF (45)
- VEGFA (42)
- FLT4 (41)
- XPD (39)
- TELOMERASE REVERSE TRANSCRIPTASE (34)
- DISC1 (32)
- MORTALITY FACTOR 4 LIKE 2 (30)
- P16INK4A (29)
- RUNX1T1 (28)
- BDNF (27)
- CBL (27)
- P21 RAS (27)
- ALPHA DYSTROGLYCAN (26)
- CD46 (26)
- KRAS (26)
- NRG1 (26)
- PLAGL1 (26)
- KCNJ15 (25)
- PDE9A (25)
- CD44 (24)
- DYSTROBREVIN ALPHA (24)
- MU OPIOID RECEPTOR (24)
- EIF5A (23)
- SYNTABULIN (23)
- ESTROGEN RELATED RECEPTOR GAMMA (22)
- ISLR2 (22)
- PKC GAMMA (22)
- E4 (21)
- MYADM (21)
- NRAS (21)
- RAF1 (21)
- BHLHB9 (20)
- CREM (20)
- MITF (20)
- ROR2 (20)
- SPHK1 (20)
- CD36 (19)
- FAM156A (19)
- PEX2 (19)
- SHUGOSHIN (19)
- SLITRK2 (19)
- STEAP2 (19)
- ARPP21 (18)
- CTNND1 (18)
- DNMT3B (18)
- FGF1 (18)
- HMGA1 (18)
- KCNE1 (18)
- MID1 (18)
- MIER1 (18)
- RNF146 (18)
- SOCS2 (18)
- SSH3BP1 (18)
- ALK (17)
- CCR6 (17)
- CEACAM1 (17)
- CONSTITUTIVE ANDROSTANE RECEPTOR (17)
- GLYPICAN 3 (17)
- GPR19 (17)
- IL1RAP (17)
- LY6E (17)
- MEIS2 (17)
- MET (17)
- P311 (17)
- PAX6 (17)
- PTGER3 (17)
- RBFOX2 (17)
- SEMA6D (17)
- SLC16A3 (17)
- TCF7L2 (17)
- TRIQK (17)
- ABL2 (16)
- BIN1 (16)
- CACNA1C (16)
- CAMKK2 (16)
- GROWTH HORMONE RECEPTOR (16)
- HHAT (16)
- IGH (16)
Vectors
Mutants
Families
- Druggable Genome (19336)
- Transmembrane (10984)
- Transcription Factors (5212)
- Secreted Protein (2591)
- Protein Kinase (2204)
- Stem cell - Pluripotency (1112)
- ES Cell Differentiation/IPS (1007)
- Protease (920)
- GPCR (753)
- Phosphatase (447)
- Ion Channels: Other (304)
- Adult stem cells (248)
- Nuclear Hormone Receptor (215)
- Ion Channels: Potassium (181)
- Embryonic stem cells (173)
- Cancer stem cells (136)
- Ion Channels: Cys-loop Receptors (107)
- Stem cell relevant signaling - JAK/STAT signaling pathway (93)
- Induced pluripotent stem cells (91)
- P450 (90)
- Ion Channels: Transient receptor potential (64)
- Ion Channels: Glutamate Receptors (53)
- Stem cell relevant signaling - DSL/Notch pathway (50)
- Ion Channels: Sodium (48)
- Stem cell relevant signaling - TGFb/BMP signaling pathway (46)
- Ion Channels: Calcium (45)
- Stem cell relevant signaling - Wnt Signaling pathway (40)
- Ion Channels: ATP Receptors (17)
- Ion Channels: Cyclic nucleotide gated (17)
Pathways
- Pathways in cancer (2590)
- Metabolic pathways (2492)
- Colorectal cancer (1110)
- MAPK signaling pathway (1102)
- Insulin signaling pathway (1049)
- Focal adhesion (872)
- Endometrial cancer (830)
- Pancreatic cancer (827)
- Regulation of actin cytoskeleton (818)
- Ubiquitin mediated proteolysis (776)
- Prostate cancer (762)
- Endocytosis (726)
- Cytokine-cytokine receptor interaction (711)
- Melanoma (708)
- Neuroactive ligand-receptor interaction (690)
- Olfactory transduction (688)
- Neurotrophin signaling pathway (664)
- B cell receptor signaling pathway (646)
- Fc epsilon RI signaling pathway (631)
- Chemokine signaling pathway (626)
- Glioma (626)
- p53 signaling pathway (611)
- Calcium signaling pathway (604)
- mTOR signaling pathway (593)
- ErbB signaling pathway (590)
- Mismatch repair (573)
- Chronic myeloid leukemia (567)
- Natural killer cell mediated cytotoxicity (559)
- Thyroid cancer (552)
- Wnt signaling pathway (546)
- Non-small cell lung cancer (543)
- Renal cell carcinoma (487)
- Tight junction (483)
- T cell receptor signaling pathway (480)
- Type II diabetes mellitus (474)
- Bladder cancer (473)
- Melanogenesis (468)
- Progesterone-mediated oocyte maturation (460)
- Jak-STAT signaling pathway (459)
- Cell cycle (456)
- GnRH signaling pathway (453)
- Huntington's disease (449)
- Small cell lung cancer (438)
- Vascular smooth muscle contraction (428)
- Axon guidance (416)
- Gap junction (413)
- Apoptosis (409)
- Leukocyte transendothelial migration (409)
- VEGF signaling pathway (409)
- Acute myeloid leukemia (402)
- Adherens junction (401)
- Glycolysis / Gluconeogenesis (396)
- Primary immunodeficiency (387)
- Long-term depression (385)
- Purine metabolism (365)
- Alzheimer's disease (354)
- Fc gamma R-mediated phagocytosis (352)
- Toll-like receptor signaling pathway (350)
- Starch and sucrose metabolism (347)
- Cell adhesion molecules (CAMs) (346)
- Long-term potentiation (344)
- Homologous recombination (343)
- Amino sugar and nucleotide sugar metabolism (329)
- Maturity onset diabetes of the young (318)
- Dilated cardiomyopathy (317)
- Oocyte meiosis (309)
- Galactose metabolism (305)
- Dorso-ventral axis formation (281)
- Arrhythmogenic right ventricular cardiomyopathy (ARVC) (274)
- Phosphatidylinositol signaling system (274)
- Basal cell carcinoma (272)
- Adipocytokine signaling pathway (262)
- Amyotrophic lateral sclerosis (ALS) (255)
- Lysosome (255)
- Notch signaling pathway (252)
- Hematopoietic cell lineage (245)
- Hypertrophic cardiomyopathy (HCM) (241)
- Systemic lupus erythematosus (229)
- Viral myocarditis (227)
- Inositol phosphate metabolism (217)
- Pyrimidine metabolism (212)
- Epithelial cell signaling in Helicobacter pylori infection (208)
- Parkinson's disease (208)
- ECM-receptor interaction (207)
- Spliceosome (207)
- TGF-beta signaling pathway (200)
- Oxidative phosphorylation (194)
- Vibrio cholerae infection (192)
- NOD-like receptor signaling pathway (186)
- Complement and coagulation cascades (177)
- Pathogenic Escherichia coli infection (177)
- PPAR signaling pathway (176)
- Antigen processing and presentation (174)
- RIG-I-like receptor signaling pathway (168)
- Cardiac muscle contraction (158)
- Taste transduction (156)
- Ribosome (150)
- Glycerophospholipid metabolism (145)
- Drug metabolism - cytochrome P450 (136)
- Metabolism of xenobiotics by cytochrome P450 (133)
- Citrate cycle (TCA cycle) (128)
- ABC transporters (124)
- Cytosolic DNA-sensing pathway (122)
- Glutathione metabolism (119)
- Arachidonic acid metabolism (115)
- Retinol metabolism (115)
- N-Glycan biosynthesis (114)
- Arginine and proline metabolism (110)
- Drug metabolism - other enzymes (109)
- Nucleotide excision repair (109)
- Valine (103)
- RNA degradation (102)
- Hedgehog signaling pathway (101)
- Lysine degradation (101)
- Type I diabetes mellitus (101)
- Autoimmune thyroid disease (100)
- Pyruvate metabolism (100)
- Prion diseases (97)
- Sphingolipid metabolism (97)
- Tyrosine metabolism (97)
- Glycerolipid metabolism (96)
- Fatty acid metabolism (93)
- Base excision repair (90)
- Cysteine and methionine metabolism (88)
- Graft-versus-host disease (85)
- leucine and isoleucine degradation (84)
- Porphyrin and chlorophyll metabolism (79)
- Allograft rejection (78)
- Androgen and estrogen metabolism (77)
- Tryptophan metabolism (74)
- Ether lipid metabolism (73)
- Propanoate metabolism (73)
- Alanine (71)
- aspartate and glutamate metabolism (71)
- Proteasome (68)
- DNA replication (67)
- Butanoate metabolism (65)
- SNARE interactions in vesicular transport (65)
- Basal transcription factors (63)
- Aminoacyl-tRNA biosynthesis (61)
- Glycine (60)
- serine and threonine metabolism (60)
- Fructose and mannose metabolism (59)
- Glycosphingolipid biosynthesis - lacto and neolacto series (58)
- Selenoamino acid metabolism (55)
- Glycosaminoglycan degradation (53)
- Nicotinate and nicotinamide metabolism (53)
- Nitrogen metabolism (53)
- Glycosylphosphatidylinositol(GPI)-anchor biosynthesis (52)
- Regulation of autophagy (52)
- Asthma (49)
- Linoleic acid metabolism (49)
- Histidine metabolism (48)
- O-Glycan biosynthesis (48)
- Phenylalanine metabolism (48)
- Pentose and glucuronate interconversions (47)
- RNA polymerase (47)
- Pentose phosphate pathway (45)
- Ascorbate and aldarate metabolism (43)
- Biosynthesis of unsaturated fatty acids (40)
- Chondroitin sulfate biosynthesis (40)
- Keratan sulfate biosynthesis (40)
- beta-Alanine metabolism (39)
- Heparan sulfate biosynthesis (38)
- Pantothenate and CoA biosynthesis (37)
- Non-homologous end-joining (36)
- One carbon pool by folate (35)
- Primary bile acid biosynthesis (34)
- Renin-angiotensin system (34)
- Riboflavin metabolism (34)
- alpha-Linolenic acid metabolism (34)
- Sulfur metabolism (32)
- Other glycan degradation (31)
- Glycosphingolipid biosynthesis - globo series (30)
- Glyoxylate and dicarboxylate metabolism (29)
- Steroid biosynthesis (29)
- Circadian rhythm - mammal (28)
- Glycosphingolipid biosynthesis - ganglio series (28)
- leucine and isoleucine biosynthesis (28)
- Terpenoid backbone biosynthesis (25)
- Limonene and pinene degradation (24)
- Taurine and hypotaurine metabolism (24)
- C21-Steroid hormone metabolism (22)
- Caffeine metabolism (20)
- Cyanoamino acid metabolism (19)
- Fatty acid biosynthesis (18)
- Synthesis and degradation of ketone bodies (18)
- Folate biosynthesis (17)
- Protein export (14)
- Fatty acid elongation in mitochondria (13)
- Phenylalanine (13)
- tyrosine and tryptophan biosynthesis (13)
- Thiamine metabolism (12)
- Ubiquinone and other terpenoid-quinone biosynthesis (11)
- Lipoic acid metabolism (10)
- Methane metabolism (9)
- Vitamin B6 metabolism (8)
- Biotin metabolism (7)
- Lysine biosynthesis (7)
- O-Mannosyl glycan biosynthesis (7)
- D-Glutamine and D-glutamate metabolism (6)
- D-Arginine and D-ornithine metabolism (1)
