IDH1 mutant (R132G), Myc-DDK-tagged ORF clone of Homo sapiens isocitrate dehydrogenase 1 (NADP+), soluble (IDH1) as transfection-ready DNA
| Mutation | R132G |
| Tag | Myc-DDK |
| Vector | pCMV6-Entry |
- TrueORF®
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IDH1 mutant (R132S), Myc-DDK-tagged ORF clone of Homo sapiens isocitrate dehydrogenase 1 (NADP+), soluble (IDH1) as transfection-ready DNA
| Mutation | R132S |
| Tag | Myc-DDK |
| Vector | pCMV6-Entry |
- TrueORF®
Atg12 (tGFP-tagged) - Mouse autophagy-related 12 (yeast) (Atg12)
| Type | Mouse Tagged ORF Clone |
| Tag | TurboGFP |
| Vector | pCMV6-AC-GFP |
- TrueORF®
Smurf1 (tGFP-tagged) - Mouse SMAD specific E3 ubiquitin protein ligase 1 (cDNA clone MGC:28022 IMAGE:3660965)
| Type | Mouse Tagged ORF Clone |
| Tag | TurboGFP |
| Vector | pCMV6-AC-GFP |
- TrueORF®
Pak2 (tGFP-tagged) - Mouse p21 (CDKN1A)-activated kinase 2 (cDNA clone MGC:65654 IMAGE:6849008)
| Type | Mouse Tagged ORF Clone |
| Tag | TurboGFP |
| Vector | pCMV6-AC-GFP |
- TrueORF®
Dnmt1 (tGFP-tagged) - Mouse DNA methyltransferase (cytosine-5) 1 (Dnmt1)
| Type | Mouse Tagged ORF Clone |
| Tag | TurboGFP |
| Vector | pCMV6-AC-GFP |
- TrueORF®
Flrt2 (tGFP-tagged) - Mouse fibronectin leucine rich transmembrane protein 2 (cDNA clone MGC:106049 IMAGE:3582155)
| Type | Mouse Tagged ORF Clone |
| Tag | TurboGFP |
| Vector | pCMV6-AC-GFP |
- TrueORF®
LRP6 (tGFP-tagged) - Human low density lipoprotein receptor-related protein 6 (LRP6)
| Type | Human Tagged ORF Clone |
| Tag | TurboGFP |
| Vector | pCMV6-AC-GFP |
- TrueORF®
ALDH1A1 (tGFP-tagged) - Human aldehyde dehydrogenase 1 family, member A1 (ALDH1A1)
| Type | Human Tagged ORF Clone |
| Tag | TurboGFP |
| Vector | pCMV6-AC-GFP |
- TrueORF®
CALCRL (tGFP-tagged) - Human calcitonin receptor-like (CALCRL)
| Type | Human Tagged ORF Clone |
| Tag | TurboGFP |
| Vector | pCMV6-AC-GFP |
- TrueORF®
KCNQ3 (tGFP-tagged) - Homo sapiens potassium voltage-gated channel, KQT-like subfamily, member 3 (KCNQ3), transcript variant 2
| Type | Human Tagged ORF Clone |
| Tag | TurboGFP |
| Vector | pCMV6-AC-GFP |
- TrueORF®
TDP1 (tGFP-tagged) - Human tyrosyl-DNA phosphodiesterase 1 (TDP1), transcript variant 1
| Type | Human Tagged ORF Clone |
| Tag | TurboGFP |
| Vector | pCMV6-AC-GFP |
- TrueORF®
MSH2 (tGFP-tagged) - Human mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli) (MSH2)
| Type | Human Tagged ORF Clone |
| Tag | TurboGFP |
| Vector | pCMV6-AC-GFP |
- TrueORF®
CYBB (tGFP-tagged) - Human cytochrome b-245, beta polypeptide (CYBB)
| Type | Human Tagged ORF Clone |
| Tag | TurboGFP |
| Vector | pCMV6-AC-GFP |
- TrueORF®
LSAMP (tGFP-tagged) - Human limbic system-associated membrane protein (LSAMP)
| Type | Human Tagged ORF Clone |
| Tag | TurboGFP |
| Vector | pCMV6-AC-GFP |
- TrueORF®
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Species
Target Symbol
- CD44 (7)
- DNMT1 (6)
- FOXM1 (6)
- ISOCITRATE DEHYDROGENASE (6)
- KRAS (6)
- AKT1 (5)
- EGFR (5)
- PD-L1 (5)
- TRPA1 (5)
- ABCG2 (4)
- C9ORF72 (4)
- CHRNA3 (4)
- CREB1 (4)
- CYP24A1 (4)
- DNMT3A (4)
- DUSP6 (4)
- FYN (4)
- LAMP2 (4)
- MET (4)
- MITF (4)
- MLH1 (4)
- MU OPIOID RECEPTOR (4)
- NRF1 (4)
- OLFM4 (4)
- P53 (4)
- P63 (4)
- PTEN (4)
- PTPRD (4)
- RHOT1 (4)
- SIRT1 (4)
- SLC22A24 (4)
- SOX6 (4)
- SPHK1 (4)
- STAT3 (4)
- TMEM16A (4)
- UCP2 (4)
- VEGFA (4)
- 5HT4 RECEPTOR (3)
- ACSL1 (3)
- ADAM17 (3)
- ADAM22 (3)
- ADAM23 (3)
- ADAR1 (3)
- AGTR1A (3)
- ALDH1A1 (3)
- ALDH1A3 (3)
- APOLIPOPROTEIN L 1 (3)
- ATG5 (3)
- B RAF (3)
- B7H3 (3)
- BACE1 (3)
- BIRC5 (3)
- BMPR2 (3)
- BRCA1 (3)
- CAMK2A (3)
- CDK4 (3)
- CEACAM1 (3)
- CERAMIDE SYNTHASE 2 (3)
- CHD4 (3)
- CXCR4 (3)
- DUSP5 (3)
- FGFR2 (3)
- FGFR3 (3)
- FOXA2 (3)
- FOXO3 (3)
- FOXP3 (3)
- FRA1 (3)
- FSTL1 (3)
- GATA6 (3)
- GFAP (3)
- GLP1R (3)
- GLYPICAN 3 (3)
- GPBAR1 (3)
- GPR120 (3)
- GRIN1 (3)
- HDAC9 (3)
- HEPARANASE 1 (3)
- HER2 (3)
- HES1 (3)
- HIF-1 ALPHA (3)
- HMGB1 (3)
- IDH2 (3)
- IGFBP1 (3)
- IGFBP7 (3)
- IKZF1 (3)
- IRF1 (3)
- IRF9 (3)
- JMJD1C (3)
- KCNMA1 (3)
- LRP5 (3)
- MC3R (3)
- MCL1 (3)
- MDM2 (3)
- MMP14 (3)
- MSH2 (3)
- MSR1 (3)
- NGF (3)
- NLRP3 (3)
- NOTCH1 (3)
- NOTCH3 (3)
Vectors
Families
- Druggable Genome (1348)
- Transmembrane (754)
- Transcription Factors (347)
- Secreted Protein (153)
- ES Cell Differentiation/IPS (150)
- Protein Kinase (150)
- GPCR (94)
- Stem cell - Pluripotency (63)
- Protease (47)
- Adult stem cells (37)
- Embryonic stem cells (33)
- Ion Channels: Potassium (30)
- Nuclear Hormone Receptor (28)
- Phosphatase (26)
- Cancer stem cells (25)
- Ion Channels: Other (25)
- Induced pluripotent stem cells (19)
- Ion Channels: Cys-loop Receptors (15)
- Stem cell relevant signaling - DSL/Notch pathway (15)
- Ion Channels: Transient receptor potential (14)
- Stem cell relevant signaling - JAK/STAT signaling pathway (14)
- Ion Channels: Sodium (10)
- P450 (9)
- Ion Channels: Glutamate Receptors (6)
- Stem cell relevant signaling - TGFb/BMP signaling pathway (6)
- Ion Channels: ATP Receptors (5)
- Ion Channels: Calcium (5)
- Stem cell relevant signaling - Wnt Signaling pathway (5)
Pathways
- Pathways in cancer (189)
- Metabolic pathways (148)
- MAPK signaling pathway (104)
- Focal adhesion (93)
- Neuroactive ligand-receptor interaction (87)
- Prostate cancer (81)
- Endocytosis (73)
- Colorectal cancer (71)
- Melanoma (69)
- Regulation of actin cytoskeleton (69)
- Chemokine signaling pathway (67)
- Cytokine-cytokine receptor interaction (67)
- Endometrial cancer (64)
- ErbB signaling pathway (64)
- Calcium signaling pathway (63)
- Neurotrophin signaling pathway (63)
- Glioma (62)
- Jak-STAT signaling pathway (59)
- Non-small cell lung cancer (58)
- Pancreatic cancer (58)
- Renal cell carcinoma (58)
- Axon guidance (56)
- Chronic myeloid leukemia (56)
- Wnt signaling pathway (53)
- Natural killer cell mediated cytotoxicity (52)
- T cell receptor signaling pathway (52)
- Insulin signaling pathway (51)
- Acute myeloid leukemia (49)
- Bladder cancer (49)
- Melanogenesis (49)
- VEGF signaling pathway (47)
- GnRH signaling pathway (44)
- Progesterone-mediated oocyte maturation (44)
- Gap junction (43)
- Adherens junction (42)
- B cell receptor signaling pathway (41)
- Cell adhesion molecules (CAMs) (41)
- Fc epsilon RI signaling pathway (41)
- Small cell lung cancer (41)
- Toll-like receptor signaling pathway (41)
- Alzheimer's disease (40)
- Cell cycle (40)
- Apoptosis (39)
- Leukocyte transendothelial migration (39)
- Fc gamma R-mediated phagocytosis (38)
- Tight junction (36)
- Long-term potentiation (35)
- p53 signaling pathway (34)
- Huntington's disease (32)
- Vascular smooth muscle contraction (32)
- Thyroid cancer (31)
- Adipocytokine signaling pathway (30)
- Long-term depression (30)
- mTOR signaling pathway (29)
- Hematopoietic cell lineage (28)
- Purine metabolism (28)
- Type II diabetes mellitus (28)
- Basal cell carcinoma (27)
- Epithelial cell signaling in Helicobacter pylori infection (27)
- TGF-beta signaling pathway (26)
- Oocyte meiosis (23)
- Phosphatidylinositol signaling system (22)
- Dorso-ventral axis formation (21)
- NOD-like receptor signaling pathway (21)
- Notch signaling pathway (21)
- Pathogenic Escherichia coli infection (21)
- Amyotrophic lateral sclerosis (ALS) (20)
- Glutathione metabolism (20)
- RIG-I-like receptor signaling pathway (20)
- Arrhythmogenic right ventricular cardiomyopathy (ARVC) (19)
- Dilated cardiomyopathy (19)
- ECM-receptor interaction (19)
- Lysosome (19)
- Prion diseases (19)
- Ubiquitin mediated proteolysis (19)
- Hedgehog signaling pathway (18)
- Hypertrophic cardiomyopathy (HCM) (18)
- Viral myocarditis (18)
- ABC transporters (17)
- Inositol phosphate metabolism (17)
- PPAR signaling pathway (16)
- Parkinson's disease (14)
- Sphingolipid metabolism (14)
- Cytosolic DNA-sensing pathway (13)
- Systemic lupus erythematosus (13)
- Antigen processing and presentation (12)
- Arachidonic acid metabolism (12)
- Pyrimidine metabolism (12)
- Type I diabetes mellitus (12)
- Allograft rejection (11)
- Autoimmune thyroid disease (11)
- Citrate cycle (TCA cycle) (11)
- Glycolysis / Gluconeogenesis (11)
- Graft-versus-host disease (11)
- Maturity onset diabetes of the young (11)
- Metabolism of xenobiotics by cytochrome P450 (11)
- Complement and coagulation cascades (10)
- Drug metabolism - cytochrome P450 (10)
- Fatty acid metabolism (10)
- Glycerophospholipid metabolism (10)
- Lysine degradation (10)
- Cysteine and methionine metabolism (9)
- Homologous recombination (9)
- Mismatch repair (9)
- Pyruvate metabolism (9)
- Retinol metabolism (9)
- Spliceosome (9)
- Base excision repair (8)
- Glycerolipid metabolism (8)
- Vibrio cholerae infection (8)
- Linoleic acid metabolism (7)
- Primary immunodeficiency (7)
- Starch and sucrose metabolism (7)
- Arginine and proline metabolism (6)
- Cardiac muscle contraction (6)
- Drug metabolism - other enzymes (6)
- Ether lipid metabolism (6)
- N-Glycan biosynthesis (6)
- Nicotinate and nicotinamide metabolism (6)
- RNA degradation (6)
- Tryptophan metabolism (6)
- Tyrosine metabolism (6)
- Galactose metabolism (5)
- Nucleotide excision repair (5)
- Olfactory transduction (5)
- Oxidative phosphorylation (5)
- Ribosome (5)
- SNARE interactions in vesicular transport (5)
- Valine (5)
- Alanine (4)
- Asthma (4)
- Biosynthesis of unsaturated fatty acids (4)
- DNA replication (4)
- Glycosaminoglycan degradation (4)
- Regulation of autophagy (4)
- Renin-angiotensin system (4)
- Taste transduction (4)
- aspartate and glutamate metabolism (4)
- Fructose and mannose metabolism (3)
- Glycine (3)
- Glycosphingolipid biosynthesis - ganglio series (3)
- Glycosphingolipid biosynthesis - lacto and neolacto series (3)
- Heparan sulfate biosynthesis (3)
- Pantothenate and CoA biosynthesis (3)
- Pentose phosphate pathway (3)
- Phenylalanine metabolism (3)
- Propanoate metabolism (3)
- alpha-Linolenic acid metabolism (3)
- leucine and isoleucine biosynthesis (3)
- leucine and isoleucine degradation (3)
- serine and threonine metabolism (3)
- Amino sugar and nucleotide sugar metabolism (2)
- Aminoacyl-tRNA biosynthesis (2)
- Androgen and estrogen metabolism (2)
- Butanoate metabolism (2)
- C21-Steroid hormone metabolism (2)
- Circadian rhythm - mammal (2)
- D-Glutamine and D-glutamate metabolism (2)
- Glycosphingolipid biosynthesis - globo series (2)
- Limonene and pinene degradation (2)
- Nitrogen metabolism (2)
- O-Glycan biosynthesis (2)
- Other glycan degradation (2)
- RNA polymerase (2)
- Caffeine metabolism (1)
- Chondroitin sulfate biosynthesis (1)
- Fatty acid biosynthesis (1)
- Folate biosynthesis (1)
- Histidine metabolism (1)
- Keratan sulfate biosynthesis (1)
- Lysine biosynthesis (1)
- Non-homologous end-joining (1)
- Porphyrin and chlorophyll metabolism (1)
- Proteasome (1)
- Riboflavin metabolism (1)
- Selenoamino acid metabolism (1)
- Steroid biosynthesis (1)
- Sulfur metabolism (1)
- Synthesis and degradation of ketone bodies (1)
- Taurine and hypotaurine metabolism (1)
- Terpenoid backbone biosynthesis (1)
- beta-Alanine metabolism (1)
