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Species
Target Symbol
- BRCA1 (404)
- BTK (299)
- BRCA2 (281)
- GLUCOKINASE (256)
- MENIN (252)
- TUBERIN (250)
- MLH1 (240)
- MSH2 (220)
- RET (192)
- NOTCH3 (163)
- P53 (118)
- NF2 (117)
- MSH6 (90)
- FGFR1 (85)
- LKB1 (85)
- WILMS TUMOR PROTEIN (78)
- G PROTEIN ALPHA S (70)
- PI 3 KINASE CATALYTIC SUBUNIT ALPHA (70)
- PDE9A (68)
- DISC1 (64)
- FH (64)
- VEGFA (63)
- NRG1 (57)
- BETA CATENIN (56)
- EGFR (56)
- BDNF (53)
- PLAGL1 (53)
- CONSTITUTIVE ANDROSTANE RECEPTOR (51)
- MORTALITY FACTOR 4 LIKE 2 (50)
- PTEN (50)
- B RAF (46)
- CREM (45)
- CD46 (44)
- FLT4 (44)
- XPD (44)
- MU OPIOID RECEPTOR (42)
- SYNTABULIN (40)
- HMGA1 (39)
- BIN1 (38)
- CD44 (38)
- ST3GAL3 (38)
- NDRG2 (37)
- RUNX1T1 (37)
- KCNJ15 (36)
- P21 RAS (36)
- SPHK1 (36)
- TELOMERASE REVERSE TRANSCRIPTASE (36)
- ALPHA 1 ANTITRYPSIN (35)
- MEIS2 (35)
- MYADM (35)
- DYSTROBREVIN ALPHA (34)
- EIF5A (34)
- FHL1 (34)
- NAT1 (33)
- OSBPL9 (33)
- PPHLN1 (33)
- SSH3BP1 (33)
- TCF7L2 (33)
- TSPAN4 (33)
- UBE2D3 (33)
- P16INK4A (32)
- ARPP21 (31)
- CD36 (31)
- CEACAM1 (31)
- FGFR2 (31)
- GM CSF RECEPTOR ALPHA (31)
- ISLR2 (31)
- NEK6 (31)
- PAX3 (31)
- YIF1B (31)
- ABLIM2 (30)
- APC11 (30)
- BHLHB9 (30)
- CAMKK2 (30)
- CHRM2 (30)
- DNMT3B (30)
- MBNL1 (30)
- OGG1 (30)
- RAD17 (30)
- SLITRK2 (30)
- TGIF (30)
- TPM1 (30)
- TTC23 (30)
- CAMK2B (29)
- CBL (29)
- CCR6 (29)
- HEXIM2 (29)
- KRAS (29)
- P311 (29)
- RHOH (29)
- SHUGOSHIN (29)
- APRATAXIN (28)
- CABYR (28)
- NCOA4 (28)
- NIPA2 (28)
- PCBP2 (28)
- PML PROTEIN (28)
- PPP2R2B (28)
- RIBONUCLEASE INHIBITOR (28)
- STEAP2 (28)
Vectors
Mutants
Families
- Druggable Genome (31701)
- Transmembrane (18874)
- Transcription Factors (8423)
- Secreted Protein (4718)
- Protein Kinase (3046)
- Stem cell - Pluripotency (1728)
- Protease (1705)
- ES Cell Differentiation/IPS (1635)
- GPCR (1190)
- Phosphatase (768)
- Ion Channels: Other (565)
- Adult stem cells (392)
- Nuclear Hormone Receptor (358)
- Embryonic stem cells (305)
- Ion Channels: Potassium (300)
- Cancer stem cells (212)
- Ion Channels: Cys-loop Receptors (174)
- P450 (166)
- Induced pluripotent stem cells (162)
- Stem cell relevant signaling - JAK/STAT signaling pathway (134)
- Ion Channels: Transient receptor potential (96)
- Stem cell relevant signaling - TGFb/BMP signaling pathway (92)
- Ion Channels: Glutamate Receptors (74)
- Stem cell relevant signaling - DSL/Notch pathway (72)
- Stem cell relevant signaling - Wnt Signaling pathway (69)
- Ion Channels: Sodium (60)
- Ion Channels: Calcium (50)
- Ion Channels: ATP Receptors (36)
- Ion Channels: Cyclic nucleotide gated (27)
Pathways
- Metabolic pathways (4556)
- Pathways in cancer (3226)
- MAPK signaling pathway (1639)
- Insulin signaling pathway (1296)
- Colorectal cancer (1254)
- Focal adhesion (1204)
- Olfactory transduction (1188)
- Regulation of actin cytoskeleton (1185)
- Cytokine-cytokine receptor interaction (1125)
- Neuroactive ligand-receptor interaction (1095)
- Endocytosis (1053)
- Ubiquitin mediated proteolysis (1043)
- Pancreatic cancer (965)
- Chemokine signaling pathway (958)
- Neurotrophin signaling pathway (949)
- Endometrial cancer (935)
- Prostate cancer (933)
- Calcium signaling pathway (886)
- Wnt signaling pathway (836)
- Melanoma (828)
- Natural killer cell mediated cytotoxicity (796)
- B cell receptor signaling pathway (794)
- Fc epsilon RI signaling pathway (768)
- ErbB signaling pathway (767)
- p53 signaling pathway (752)
- Glioma (740)
- Huntington's disease (739)
- Tight junction (731)
- Jak-STAT signaling pathway (711)
- Chronic myeloid leukemia (703)
- Cell cycle (696)
- mTOR signaling pathway (688)
- T cell receptor signaling pathway (686)
- Progesterone-mediated oocyte maturation (685)
- Purine metabolism (681)
- Melanogenesis (654)
- Leukocyte transendothelial migration (648)
- Non-small cell lung cancer (646)
- Thyroid cancer (643)
- GnRH signaling pathway (638)
- Axon guidance (631)
- Alzheimer's disease (616)
- Renal cell carcinoma (614)
- Mismatch repair (613)
- Vascular smooth muscle contraction (610)
- Small cell lung cancer (597)
- Apoptosis (591)
- Gap junction (563)
- Cell adhesion molecules (CAMs) (560)
- VEGF signaling pathway (560)
- Adherens junction (556)
- Oocyte meiosis (552)
- Glycolysis / Gluconeogenesis (545)
- Bladder cancer (542)
- Type II diabetes mellitus (541)
- Toll-like receptor signaling pathway (534)
- Fc gamma R-mediated phagocytosis (532)
- Acute myeloid leukemia (527)
- Long-term depression (513)
- Dilated cardiomyopathy (505)
- Lysosome (498)
- Long-term potentiation (470)
- Systemic lupus erythematosus (460)
- Primary immunodeficiency (459)
- Arrhythmogenic right ventricular cardiomyopathy (ARVC) (431)
- Starch and sucrose metabolism (428)
- Hematopoietic cell lineage (427)
- Amino sugar and nucleotide sugar metabolism (419)
- Hypertrophic cardiomyopathy (HCM) (419)
- Spliceosome (418)
- Phosphatidylinositol signaling system (397)
- Homologous recombination (396)
- Adipocytokine signaling pathway (394)
- Parkinson's disease (391)
- Pyrimidine metabolism (382)
- Oxidative phosphorylation (369)
- Basal cell carcinoma (362)
- Galactose metabolism (360)
- Maturity onset diabetes of the young (356)
- Amyotrophic lateral sclerosis (ALS) (354)
- Viral myocarditis (354)
- Antigen processing and presentation (353)
- TGF-beta signaling pathway (350)
- ECM-receptor interaction (322)
- PPAR signaling pathway (321)
- Epithelial cell signaling in Helicobacter pylori infection (320)
- Complement and coagulation cascades (319)
- Notch signaling pathway (319)
- Dorso-ventral axis formation (318)
- NOD-like receptor signaling pathway (318)
- Inositol phosphate metabolism (313)
- Vibrio cholerae infection (298)
- Pathogenic Escherichia coli infection (295)
- Cardiac muscle contraction (294)
- RIG-I-like receptor signaling pathway (293)
- Ribosome (284)
- Glycerophospholipid metabolism (278)
- Metabolism of xenobiotics by cytochrome P450 (253)
- Drug metabolism - cytochrome P450 (251)
- Arginine and proline metabolism (237)
- Taste transduction (230)
- Cytosolic DNA-sensing pathway (226)
- Valine (218)
- Glutathione metabolism (212)
- RNA degradation (208)
- Retinol metabolism (206)
- Arachidonic acid metabolism (205)
- Drug metabolism - other enzymes (199)
- N-Glycan biosynthesis (196)
- Citrate cycle (TCA cycle) (193)
- Nucleotide excision repair (188)
- Pyruvate metabolism (188)
- Autoimmune thyroid disease (186)
- Hedgehog signaling pathway (186)
- Fatty acid metabolism (184)
- Tyrosine metabolism (184)
- leucine and isoleucine degradation (182)
- Glycerolipid metabolism (180)
- Lysine degradation (173)
- Sphingolipid metabolism (173)
- ABC transporters (172)
- Type I diabetes mellitus (169)
- Base excision repair (165)
- Cysteine and methionine metabolism (159)
- Proteasome (159)
- Prion diseases (157)
- Graft-versus-host disease (149)
- Alanine (147)
- Tryptophan metabolism (147)
- aspartate and glutamate metabolism (147)
- Porphyrin and chlorophyll metabolism (144)
- Propanoate metabolism (139)
- Androgen and estrogen metabolism (135)
- Ether lipid metabolism (135)
- Allograft rejection (134)
- Butanoate metabolism (133)
- Fructose and mannose metabolism (131)
- DNA replication (129)
- SNARE interactions in vesicular transport (129)
- Aminoacyl-tRNA biosynthesis (123)
- Glycosphingolipid biosynthesis - lacto and neolacto series (121)
- Glycine (118)
- serine and threonine metabolism (118)
- Selenoamino acid metabolism (116)
- Basal transcription factors (114)
- Pentose phosphate pathway (110)
- Histidine metabolism (109)
- Nitrogen metabolism (108)
- Regulation of autophagy (108)
- Glycosaminoglycan degradation (102)
- O-Glycan biosynthesis (98)
- Linoleic acid metabolism (97)
- Glycosylphosphatidylinositol(GPI)-anchor biosynthesis (95)
- Nicotinate and nicotinamide metabolism (94)
- RNA polymerase (88)
- Asthma (87)
- Phenylalanine metabolism (87)
- Pentose and glucuronate interconversions (86)
- Pantothenate and CoA biosynthesis (81)
- beta-Alanine metabolism (79)
- Ascorbate and aldarate metabolism (76)
- Biosynthesis of unsaturated fatty acids (76)
- Keratan sulfate biosynthesis (76)
- Heparan sulfate biosynthesis (75)
- One carbon pool by folate (72)
- Sulfur metabolism (72)
- Chondroitin sulfate biosynthesis (70)
- alpha-Linolenic acid metabolism (65)
- Other glycan degradation (64)
- Primary bile acid biosynthesis (64)
- Riboflavin metabolism (64)
- Non-homologous end-joining (63)
- Renin-angiotensin system (62)
- Glyoxylate and dicarboxylate metabolism (61)
- Steroid biosynthesis (60)
- Glycosphingolipid biosynthesis - globo series (58)
- Terpenoid backbone biosynthesis (58)
- leucine and isoleucine biosynthesis (56)
- Glycosphingolipid biosynthesis - ganglio series (55)
- Circadian rhythm - mammal (53)
- Limonene and pinene degradation (49)
- Taurine and hypotaurine metabolism (47)
- C21-Steroid hormone metabolism (43)
- Cyanoamino acid metabolism (39)
- Folate biosynthesis (39)
- Caffeine metabolism (36)
- Synthesis and degradation of ketone bodies (34)
- Fatty acid elongation in mitochondria (32)
- Fatty acid biosynthesis (29)
- Thiamine metabolism (28)
- Ubiquinone and other terpenoid-quinone biosynthesis (28)
- Protein export (27)
- Lipoic acid metabolism (21)
- Phenylalanine (21)
- tyrosine and tryptophan biosynthesis (21)
- Methane metabolism (20)
- Lysine biosynthesis (15)
- Vitamin B6 metabolism (15)
- D-Glutamine and D-glutamate metabolism (12)
- O-Mannosyl glycan biosynthesis (12)
- Biotin metabolism (10)
- D-Arginine and D-ornithine metabolism (3)
