Rabbit Polyclonal TSC2 Antibody
| Applications | WB |
| Reactivities | Human, Mouse |
Antibodies
Rabbit Polyclonal LSD1 Antibody
| Applications | WB |
| Reactivities | Human, Mouse, Rat |
Rabbit Polyclonal CTRP1 Antibody
| Applications | WB |
| Reactivities | Human, Mouse |
Rabbit Polyclonal Akirin1 Antibody
| Applications | WB |
| Reactivities | Human, Mouse, Rat |
Rabbit Polyclonal LGP2 Antibody
| Applications | WB |
| Reactivities | Human, Mouse, Rat |
Rabbit Polyclonal UBC13 Antibody
| Applications | ELISA, IF, IHC, WB |
| Reactivities | Human, Mouse, Rat |
Rabbit Polyclonal IRE1p Antibody
| Applications | WB |
| Reactivities | Human |
Rabbit Polyclonal CTRP7 Antibody
| Applications | ELISA, ICC, WB |
| Reactivities | Human, Mouse, Rat |
Rabbit Polyclonal CTRP5 Antibody
| Applications | WB |
| Reactivities | Human |
Rabbit Polyclonal LGI2 Antibody
| Applications | WB |
| Reactivities | Human, Mouse, Rat |
Rabbit Polyclonal UEV1A Antibody
| Applications | WB |
| Reactivities | Human, Mouse, Rat |
Rabbit Polyclonal PHAP I Antibody
| Applications | ELISA, IF, IHC, WB |
| Reactivities | Human, Mouse, Rat |
Rabbit Polyclonal CTRP2 Antibody
| Applications | ELISA, ICC, IF, WB |
| Reactivities | Human, Mouse, Rat |
Rabbit Polyclonal Unc93a Antibody
| Applications | WB |
| Reactivities | Human |
Rabbit Polyclonal APH1 Antibody
| Applications | WB |
| Reactivities | Human, Mouse |
活动过滤器
优化搜索结果
Target Symbol
- EGFR (110)
- AKT1 (102)
- MAPT (94)
- TP53 (73)
- H3FA (66)
- JUN (59)
- IRS1 (57)
- RAF1 (56)
- STAT3 (56)
- H3C1 (55)
- SMAD3 (53)
- HIST1H2BC (52)
- NFKB1 (51)
- ATF2 (49)
- RELA (49)
- JAK2 (48)
- HIST2H3A (46)
- CREB1 (45)
- BCL2 (43)
- NF-KB P65 (42)
- FOXO1 (41)
- RB1 (41)
- SMAD2 (41)
- EIF4EBP1 (40)
- MAP2K1 (40)
- MET (40)
- CDK1 (39)
- KDR (39)
- APP (38)
- BAD (38)
- STAT1 (38)
- MTOR (37)
- PTEN (36)
- STAT5A (36)
- CTNNB1 (35)
- ERBB2 (35)
- ZAP70 (35)
- ESR1 (34)
- GJA1 (33)
- P53 (33)
- HIST1H1C (32)
- SRC (32)
- VASP (32)
- BRCA1 (31)
- ELK1 (31)
- HIST1H2AG (31)
- PAK1 (31)
- RPS6KA1 (31)
- CAMK2A (30)
- GSK3B (30)
- STAT6 (30)
- CHEK1 (29)
- TAU (29)
- VEGFA (29)
- HDAC5 (28)
- HSPB1 (28)
- RPS6 (28)
- CDC25A (27)
- GFAP (27)
- CDK2 (26)
- H3FT (26)
- HDAC1 (26)
- MAP3K5 (26)
- SQSTM1 (26)
- VEGF RECEPTOR 2 (26)
- DOK1 (25)
- JUNB (25)
- MDM2 (25)
- MEF2A (25)
- NPPA (25)
- POMC (25)
- SMAD1 (25)
- YAP1 (25)
- BETA CATENIN (24)
- FOXO4 (24)
- GRIA1 (24)
- HSF1 (24)
- P38 (24)
- RUNX1 (24)
- S6K1 (24)
- BCAR1 (23)
- BRAF (23)
- CASPASE 9 (23)
- CBL (23)
- GAPDH (23)
- GCG (23)
- ICAM1 (23)
- LRRK2 (23)
- MCL1 (23)
- MEK1 (23)
- PRKCD (23)
- PTK2 (23)
- SNCA (23)
- STMN1 (23)
- SYK (23)
- ALPHA SYNUCLEIN (22)
- BAX (22)
- CASPASE 3 (22)
- FGFR1 (22)
- GRIN1 (22)
Applications
- WB (57487)
- IHC (40176)
- ELISA (16712)
- IF (6476)
- ICC/IF (5757)
- IP (1912)
- FC (1384)
- ChIP (250)
- Dot (157)
- Simple Western (150)
- ID (87)
- ICC (74)
- PEP-ELISA (64)
- R (59)
- Immunoblotting (50)
- FN (27)
- ChIP-seq (26)
- 10k-ChIP (11)
- EMSA (11)
- Electron Microscopy (11)
- Block/Neutralize (9)
- SDS-PAGE (6)
- E (5)
- RIP (4)
- CT (3)
- AGG (2)
- EM (2)
- Ie (2)
- Neutralize (2)
- MA (1)
- Protein Array (1)
Antibody Hosts
Knockout (KO) Validation
Conjugates
Modifications
- Unmodified (10105)
- Phospho-specific (856)
- Phospho S83 (8)
- Acetyl K5 (6)
- Phospho S376 (6)
- Acetyl K16 (4)
- Acetyl K36 (4)
- Phospho S104 (4)
- Phospho S129 (4)
- Phospho S16 (4)
- Phospho S21 (4)
- Phospho S319 (4)
- Phospho S380 (4)
- Phospho S727 (4)
- Phospho S9 (4)
- Phospho T286 (4)
- Phospho T389 (4)
- Phospho T514 (4)
- Phospho Y410 (4)
- Acetyl K12 (3)
- Acetyl K4 (3)
- Phospho S139 (3)
- TriMethyl K56 (3)
- Acetyl K14 (2)
- Acetyl K15 (2)
- Acetyl K27 (2)
- Acetyl K29 (2)
- Acetyl K332 (2)
- Acetyl K9/K14/K18/K23/K27 (2)
- Acetyl K91 (2)
- Asymmetric DiMethyl R3 (2)
- K29-linkage Specific Polyubiquitin (2)
- K33-linkage Specific Polyubiquitin (2)
- MonoMethyl K342 (2)
- MonoMethyl K5 (2)
- Pan DiMethyl-lysine (2)
- Phospho Phospho S87 (2)
- Phospho S1 (2)
- Phospho S10 (2)
- Phospho S1033 (2)
- Phospho S11 (2)
- Phospho S1105 (2)
- Phospho S1108 (2)
- Phospho S1177 (2)
- Phospho S1248 (2)
- Phospho S127 (2)
- Phospho S128 (2)
- Phospho S1387 (2)
- Phospho S1490 (2)
- Phospho S15 (2)
- Phospho S157 (2)
- Phospho S16/T17 (2)
- Phospho S166 (2)
- Phospho S180 (2)
- Phospho S182 (2)
- Phospho S189,Phospho S207 (2)
- Phospho S19 (2)
- Phospho S194 (2)
- Phospho S1943 (2)
- Phospho S1981 (2)
- Phospho S2 (2)
- Phospho S20 (2)
- Phospho S2056 (2)
- Phospho S209 (2)
- Phospho S211 (2)
- Phospho S2152 (2)
- Phospho S22 (2)
- Phospho S235/236 (2)
- Phospho S240/244 (2)
- Phospho S241 (2)
- Phospho S243 (2)
- Phospho S2481 (2)
- Phospho S253 (2)
- Phospho S257/T261 (2)
- Phospho S259 (2)
- Phospho S271 (2)
- Phospho S28 (2)
- Phospho S280 (2)
- Phospho S29/33/37/T41 (2)
- Phospho S293 (2)
- Phospho S294 (2)
- Phospho S298 (2)
- Phospho S307 (2)
- Phospho S308,Phospho S309,Phospho S305 (2)
- Phospho S33 (2)
- Phospho S33/S37/T41 (2)
- Phospho S330 (2)
- Phospho S334 (2)
- Phospho S338 (2)
- Phospho S345 (2)
- Phospho S36 (2)
- Phospho S366 (2)
- Phospho S37 (2)
- Phospho S380/T382/383 (2)
- Phospho S39 (2)
- Phospho S392 (2)
- Phospho S396 (2)
- Phospho S409/S410 (2)
- Phospho S412 (2)
- Phospho S420 (2)
- Phospho S422 (2)
- Phospho S423/S425 (2)
- Phospho S425 (2)
- Phospho S428 (2)
- Phospho S445 (2)
- Phospho S448 (2)
- Phospho S45 (2)
- Phospho S455 (2)
- Phospho S46 (2)
- Phospho S465/S467 (2)
- Phospho S467 (2)
- Phospho S473 (2)
- Phospho S473,Phospho S474,Phospho S472 (2)
- Phospho S483 (2)
- Phospho S485 (2)
- Phospho S5 (2)
- Phospho S505 (2)
- Phospho S507 (2)
- Phospho S51 (2)
- Phospho S516 (2)
- Phospho S529 (2)
- Phospho S552 (2)
- Phospho S555 (2)
- Phospho S56 (2)
- Phospho S563 (2)
- Phospho S588 (2)
- Phospho S6 (2)
- Phospho S608 (2)
- Phospho S611/615 (2)
- Phospho S611/615/616 (2)
- Phospho S616 (2)
- Phospho S62 (2)
- Phospho S621 (2)
- Phospho S63 (2)
- Phospho S636/639 (2)
- Phospho S638 (2)
- Phospho S641 (2)
- Phospho S643/676 (2)
- Phospho S645 (2)
- Phospho S65 (2)
- Phospho S657/Y658 (2)
- Phospho S668 (2)
- Phospho S675 (2)
- Phospho S7 (2)
- Phospho S70 (2)
- Phospho S71 (2)
- Phospho S728 (2)
- Phospho S73 (2)
- Phospho S744/748 (2)
- Phospho S795 (2)
- Phospho S807/811 (2)
- Phospho S811 (2)
- Phospho S838/S840 (2)
- Phospho S886 (2)
- Phospho S89 (2)
- Phospho S890 (2)
- Phospho S896/S897 (2)
- Phospho S897 (2)
- Phospho S916 (2)
- Phospho S957 (2)
- Phospho S967 (2)
- Phospho Ser15 (2)
- Phospho Ser404 (2)
- Phospho Ser416 (2)
- Phospho Ser792 (2)
- Phospho Ser90 (2)
- Phospho T11 (2)
- Phospho T117 (2)
- Phospho T14 (2)
- Phospho T1462 (2)
- Phospho T156 (2)
- Phospho T163 (2)
- Phospho T17 (2)
- Phospho T172 (2)
- Phospho T179 (2)
- Phospho T18/S19 (2)
- Phospho T180/Y182 + T183/Y1845 (2)
- Phospho T181 (2)
- Phospho T183/Y185 (2)
- Phospho T183/Y185,Phospho T221/Y223 (2)
- Phospho T186 (2)
- Phospho T189 (2)
- Phospho T197 (2)
- Phospho T1989 (2)
- Phospho T199 (2)
- Phospho T204 (2)
- Phospho T217 (2)
- Phospho T232 (2)
- Phospho T235 (2)
- Phospho T24,Phospho T32,Phospho T28 (2)
- Phospho T246 (2)
- Phospho T261 (2)
- Phospho T288 (2)
- Phospho T288,Phospho T232,Phospho T198 (2)
- Phospho T292 (2)
- Phospho T3 (2)
- Phospho T308 (2)
- Phospho T32 (2)
- Phospho T320 (2)
- Phospho T334 (2)
- Phospho T346 (2)
- Phospho T359 (2)
- Phospho T359/S363 (2)
- Phospho T384 (2)
- Phospho T387 (2)
- Phospho T395 (2)
- Phospho T410 (2)
- Phospho T421/S424 (2)
- Phospho T434 (2)
- Phospho T446 (2)
- Phospho T45 (2)
- Phospho T498 (2)
- Phospho T505 (2)
- Phospho T538 (2)
- Phospho T56 (2)
- Phospho T567,Phospho T564,Phospho T558 (2)
- Phospho T58 (2)
- Phospho T642 (2)
- Phospho T669 (2)
- Phospho T69/71 (2)
- Phospho T69/T71 (2)
- Phospho T696 (2)
- Phospho T70 (2)
- Phospho T81 (2)
- Phospho T853 (2)
- Phospho T91 (2)
- Phospho T918 (2)
- Phospho T93 (2)
- Phospho Thr212/Ser214 (2)
- Phospho Y1007 (2)
- Phospho Y1008 (2)
- Phospho Y1020 (2)
- Phospho Y1021 (2)
- Phospho Y1045 (2)
- Phospho Y1086 (2)
- Phospho Y1096 (2)
- Phospho Y1148 (2)
- Phospho Y1173 (2)
- Phospho Y1175 (2)
- Phospho Y1217 (2)
- Phospho Y1221/1222 (2)
- Phospho Y1234/1235 (2)
- Phospho Y1284 (2)
- Phospho Y1349 (2)
- Phospho Y14 (2)
- Phospho Y145 (2)
- Phospho Y1474 (2)
- Phospho Y15 (2)
- Phospho Y165 (2)
- Phospho Y171 (2)
- Phospho Y177 (2)
- Phospho Y182 (2)
- Phospho Y191 (2)
- Phospho Y207 (2)
- Phospho Y216 (2)
- Phospho Y221 (2)
- Phospho Y245 (2)
- Phospho Y307 (2)
- Phospho Y311 (2)
- Phospho Y340 (2)
- Phospho Y353 (2)
- Phospho Y412 (2)
- Phospho Y564 (2)
- Phospho Y576/577 (2)
- Phospho Y589/591 (2)
- Phospho Y594 (2)
- Phospho Y653 (2)
- Phospho Y659 (2)
- Phospho Y674/675 + Y706/707 (2)
- Phospho Y694 (2)
- Phospho Y700 (2)
- Phospho Y708 (2)
- Phospho Y719 (2)
- Phospho Y724 (2)
- Phospho Y751 (2)
- Phospho Y754 (2)
- Phospho Y759 (2)
- Phospho Y789 (2)
- Phospho Y792 (2)
- Phospho Y845 (2)
- Phospho Y849 (2)
- Phospho Y869 (2)
- Phospho Y925 (2)
- Phospho Y992 (2)
- Phospho Y998 (2)
- Phospho pS221 (2)
- Phospho-(Ser/Thr) (2)
- Phospho-PKC (pan) (βII Ser660) (2)
- Phospho-RPS6KB1-S371 (2)
- Ubiquityl K119 (2)
- monoMethyl E105 (2)
- pan Symmetric-DiMethyl-Arginine (2)
- pan-Di-Methyl K (2)
- pan-Mono-Methyl K (2)
- pan-Mono-MethylR（R*GG） (2)
- pan-TriMethyl-lysine (2)
- Acetyl K18 (1)
- Acetyl K23 (1)
- Acetyl K56 (1)
- Acetyl K8 (1)
- Acetyl K9 (1)
- MonoMethyl K36 (1)
- Phospho S326 (1)
- Phospho S397 (1)
- Phospho S82 (1)
- Phospho T180/Y182 (1)
- Phospho T202/Y204 + T185/Y187 (1)
- Phospho Y1007/1008 (1)
- Phospho Y1165/1166,Phospho Y1189/1190 (1)
- Phospho Y1189/Y1190,Phospho Y1165/Y1166 (1)
- Phospho Y705 (1)
- pan Phospho-Serine/Threonine (1)
- pan-tri-Methyl K (1)
Isotypes
Assay Types
Brands
Families
- Druggable Genome (17571)
- Transmembrane (8731)
- Transcription Factors (4342)
- Secreted Protein (2815)
- Protein Kinase (2041)
- ES Cell Differentiation/IPS (1639)
- Stem cell - Pluripotency (1109)
- Protease (1018)
- GPCR (895)
- Phosphatase (334)
- Adult stem cells (331)
- Embryonic stem cells (280)
- Ion Channels: Other (240)
- Cancer stem cells (230)
- Nuclear Hormone Receptor (216)
- Stem cell relevant signaling - JAK/STAT signaling pathway (216)
- Induced pluripotent stem cells (176)
- Ion Channels: Potassium (143)
- P450 (127)
- Stem cell relevant signaling - DSL/Notch pathway (104)
- Stem cell relevant signaling - TGFb/BMP signaling pathway (104)
- Ion Channels: Glutamate Receptors (91)
- Stem cell relevant signaling - Wnt Signaling pathway (90)
- Ion Channels: Transient receptor potential (86)
- Ion Channels: Cys-loop Receptors (76)
- Ion Channels: Sodium (46)
- Ion Channels: Cyclic nucleotide gated (22)
- Ion Channels: ATP Receptors (13)
- Ion Channels: Calcium (13)
Pathways
- Metabolic pathways (2272)
- Pathways in cancer (2089)
- MAPK signaling pathway (1306)
- Focal adhesion (1132)
- Cytokine-cytokine receptor interaction (956)
- Neurotrophin signaling pathway (895)
- Chemokine signaling pathway (878)
- Neuroactive ligand-receptor interaction (877)
- Regulation of actin cytoskeleton (863)
- Prostate cancer (854)
- Cell cycle (719)
- ErbB signaling pathway (711)
- Insulin signaling pathway (710)
- Chronic myeloid leukemia (701)
- Colorectal cancer (678)
- Pancreatic cancer (676)
- Jak-STAT signaling pathway (665)
- T cell receptor signaling pathway (665)
- Endocytosis (663)
- Calcium signaling pathway (661)
- Wnt signaling pathway (641)
- Alzheimer's disease (637)
- Apoptosis (637)
- Small cell lung cancer (627)
- Toll-like receptor signaling pathway (615)
- Leukocyte transendothelial migration (606)
- Huntington's disease (579)
- Acute myeloid leukemia (542)
- Adipocytokine signaling pathway (540)
- Melanoma (528)
- Olfactory transduction (516)
- Fc gamma R-mediated phagocytosis (513)
- Natural killer cell mediated cytotoxicity (510)
- Glioma (508)
- Tight junction (502)
- B cell receptor signaling pathway (499)
- Progesterone-mediated oocyte maturation (494)
- VEGF signaling pathway (488)
- Endometrial cancer (487)
- GnRH signaling pathway (485)
- Adherens junction (472)
- Non-small cell lung cancer (471)
- Axon guidance (469)
- Oocyte meiosis (455)
- Renal cell carcinoma (450)
- p53 signaling pathway (447)
- Melanogenesis (446)
- Epithelial cell signaling in Helicobacter pylori infection (438)
- Gap junction (438)
- Vascular smooth muscle contraction (424)
- Fc epsilon RI signaling pathway (409)
- TGF-beta signaling pathway (409)
- Amyotrophic lateral sclerosis (ALS) (398)
- Cell adhesion molecules (CAMs) (390)
- Systemic lupus erythematosus (387)
- NOD-like receptor signaling pathway (383)
- Ubiquitin mediated proteolysis (383)
- Bladder cancer (380)
- RIG-I-like receptor signaling pathway (359)
- mTOR signaling pathway (357)
- Parkinson's disease (353)
- Long-term potentiation (335)
- Long-term depression (321)
- Hematopoietic cell lineage (308)
- Purine metabolism (304)
- Pathogenic Escherichia coli infection (298)
- Type II diabetes mellitus (275)
- Hypertrophic cardiomyopathy (HCM) (271)
- Dilated cardiomyopathy (267)
- Arrhythmogenic right ventricular cardiomyopathy (ARVC) (256)
- ECM-receptor interaction (249)
- Cytosolic DNA-sensing pathway (239)
- Complement and coagulation cascades (238)
- Lysosome (236)
- PPAR signaling pathway (236)
- Antigen processing and presentation (230)
- Viral myocarditis (227)
- Basal cell carcinoma (220)
- Thyroid cancer (216)
- Glycolysis / Gluconeogenesis (207)
- Spliceosome (203)
- Oxidative phosphorylation (201)
- Phosphatidylinositol signaling system (184)
- Metabolism of xenobiotics by cytochrome P450 (176)
- Pyrimidine metabolism (175)
- Prion diseases (172)
- Arginine and proline metabolism (158)
- Hedgehog signaling pathway (158)
- Notch signaling pathway (157)
- Drug metabolism - cytochrome P450 (156)
- Vibrio cholerae infection (150)
- Arachidonic acid metabolism (149)
- Primary immunodeficiency (147)
- Cardiac muscle contraction (146)
- Dorso-ventral axis formation (145)
- Type I diabetes mellitus (139)
- Ribosome (138)
- Retinol metabolism (137)
- Tyrosine metabolism (121)
- Pyruvate metabolism (120)
- Valine (120)
- ABC transporters (118)
- RNA degradation (117)
- Glycerophospholipid metabolism (115)
- Base excision repair (111)
- Fatty acid metabolism (111)
- Inositol phosphate metabolism (111)
- Proteasome (111)
- Glycerolipid metabolism (109)
- Autoimmune thyroid disease (107)
- Fructose and mannose metabolism (107)
- Nucleotide excision repair (107)
- leucine and isoleucine degradation (107)
- Alanine (104)
- aspartate and glutamate metabolism (104)
- DNA replication (103)
- Drug metabolism - other enzymes (103)
- Glutathione metabolism (103)
- Regulation of autophagy (103)
- Citrate cycle (TCA cycle) (102)
- Tryptophan metabolism (102)
- Allograft rejection (101)
- Cysteine and methionine metabolism (101)
- Graft-versus-host disease (98)
- Androgen and estrogen metabolism (95)
- Butanoate metabolism (95)
- Homologous recombination (92)
- Starch and sucrose metabolism (91)
- Taste transduction (85)
- Sphingolipid metabolism (83)
- Porphyrin and chlorophyll metabolism (81)
- Lysine degradation (77)
- Maturity onset diabetes of the young (74)
- Histidine metabolism (72)
- Renin-angiotensin system (72)
- SNARE interactions in vesicular transport (69)
- Linoleic acid metabolism (68)
- Mismatch repair (68)
- Phenylalanine metabolism (68)
- Propanoate metabolism (67)
- Glycine (66)
- Nitrogen metabolism (66)
- serine and threonine metabolism (66)
- Amino sugar and nucleotide sugar metabolism (64)
- Ether lipid metabolism (64)
- beta-Alanine metabolism (62)
- Basal transcription factors (61)
- N-Glycan biosynthesis (60)
- Asthma (58)
- Non-homologous end-joining (57)
- Aminoacyl-tRNA biosynthesis (55)
- Pentose phosphate pathway (55)
- Galactose metabolism (50)
- Nicotinate and nicotinamide metabolism (48)
- Pentose and glucuronate interconversions (46)
- Biosynthesis of unsaturated fatty acids (43)
- Ascorbate and aldarate metabolism (42)
- Heparan sulfate biosynthesis (42)
- Riboflavin metabolism (42)
- O-Glycan biosynthesis (40)
- Glycosaminoglycan degradation (39)
- Primary bile acid biosynthesis (39)
- Glyoxylate and dicarboxylate metabolism (37)
- Selenoamino acid metabolism (37)
- Chondroitin sulfate biosynthesis (36)
- RNA polymerase (35)
- C21-Steroid hormone metabolism (33)
- Terpenoid backbone biosynthesis (33)
- Steroid biosynthesis (31)
- Taurine and hypotaurine metabolism (31)
- Folate biosynthesis (30)
- Limonene and pinene degradation (30)
- Pantothenate and CoA biosynthesis (30)
- alpha-Linolenic acid metabolism (30)
- Circadian rhythm - mammal (28)
- Glycosphingolipid biosynthesis - lacto and neolacto series (27)
- Other glycan degradation (27)
- One carbon pool by folate (25)
- Glycosphingolipid biosynthesis - ganglio series (23)
- Glycosylphosphatidylinositol(GPI)-anchor biosynthesis (22)
- Methane metabolism (19)
- Phenylalanine (18)
- Synthesis and degradation of ketone bodies (18)
- tyrosine and tryptophan biosynthesis (18)
- leucine and isoleucine biosynthesis (17)
- Keratan sulfate biosynthesis (16)
- Protein export (16)
- Fatty acid elongation in mitochondria (15)
- Thiamine metabolism (15)
- Caffeine metabolism (14)
- Sulfur metabolism (14)
- Ubiquinone and other terpenoid-quinone biosynthesis (13)
- Fatty acid biosynthesis (12)
- Glycosphingolipid biosynthesis - globo series (12)
- D-Glutamine and D-glutamate metabolism (9)
- Vitamin B6 metabolism (9)
- Cyanoamino acid metabolism (8)
- Lysine biosynthesis (7)
- Lipoic acid metabolism (6)
- O-Mannosyl glycan biosynthesis (5)
- D-Arginine and D-ornithine metabolism (2)
- Biotin metabolism (1)
