Expression Plasmids

cDNA Clones

Expression Plasmids

Human

AKR1B10

GAD65

L2HGDH

Plasmids

mGFP

pCMV6-Entry

pCMV6-AC-GFP

pCMV6-XL5

pLenti-C-Myc-DDK

pLenti-C-mGFP-P2A-Puro

pCMV6-AC

pCMV6-XL4

pLenti-C-Myc-DDK-P2A-Puro

pLenti-C-mGFP

PCMV6-Neo

No

LentiORF

Druggable Genome

Pathways in cancer

Metabolic pathways

MAPK signaling pathway

Cytokine-cytokine receptor interaction

Focal adhesion

Chemokine signaling pathway

Regulation of actin cytoskeleton

Neurotrophin signaling pathway

Natural killer cell mediated cytotoxicity

Cell adhesion molecules (CAMs)

Endocytosis

Jak-STAT signaling pathway

Prostate cancer

T cell receptor signaling pathway

Tight junction

Wnt signaling pathway

Fc gamma R-mediated phagocytosis

Neuroactive ligand-receptor interaction

B cell receptor signaling pathway

Insulin signaling pathway

Melanoma

Colorectal cancer

ErbB signaling pathway

Leukocyte transendothelial migration

Pancreatic cancer

Toll-like receptor signaling pathway

Apoptosis

Axon guidance

Chronic myeloid leukemia

Glioma

VEGF signaling pathway

Calcium signaling pathway

Fc epsilon RI signaling pathway

Hematopoietic cell lineage

Acute myeloid leukemia

Adherens junction

Adipocytokine signaling pathway

Non-small cell lung cancer

Small cell lung cancer

Renal cell carcinoma

Alzheimer's disease

Bladder cancer

Melanogenesis

TGF-beta signaling pathway

GnRH signaling pathway

Cell cycle

Huntington's disease

Endometrial cancer

Gap junction

Progesterone-mediated oocyte maturation

Systemic lupus erythematosus

Ubiquitin mediated proteolysis

Vascular smooth muscle contraction

mTOR signaling pathway

Epithelial cell signaling in Helicobacter pylori infection

p53 signaling pathway

Lysosome

Antigen processing and presentation

Long-term depression

Basal cell carcinoma

ECM-receptor interaction

Hypertrophic cardiomyopathy (HCM)

Maturity onset diabetes of the young

RIG-I-like receptor signaling pathway

Type II diabetes mellitus

Viral myocarditis

Complement and coagulation cascades

Long-term potentiation

Parkinson's disease

Thyroid cancer

Dilated cardiomyopathy

NOD-like receptor signaling pathway

Amyotrophic lateral sclerosis (ALS)

Arrhythmogenic right ventricular cardiomyopathy (ARVC)

Oocyte meiosis

Hedgehog signaling pathway

Pathogenic Escherichia coli infection

Phosphatidylinositol signaling system

Autoimmune thyroid disease

Glutathione metabolism

PPAR signaling pathway

Primary immunodeficiency

Purine metabolism

Spliceosome

Vibrio cholerae infection

Cytosolic DNA-sensing pathway

Glycolysis / Gluconeogenesis

Graft-versus-host disease

Prion diseases

Sphingolipid metabolism

Allograft rejection

Arachidonic acid metabolism

Citrate cycle (TCA cycle)

Notch signaling pathway

Type I diabetes mellitus

Alanine

Dorso-ventral axis formation

Nitrogen metabolism

Pyruvate metabolism

aspartate and glutamate metabolism

Arginine and proline metabolism

Circadian rhythm - mammal

Ether lipid metabolism

Glycerophospholipid metabolism

Inositol phosphate metabolism

Metabolism of xenobiotics by cytochrome P450

Oxidative phosphorylation

Phenylalanine metabolism

Tryptophan metabolism

Tyrosine metabolism

Regulation of autophagy

ABC transporters

Amino sugar and nucleotide sugar metabolism

Drug metabolism - cytochrome P450

Glycerolipid metabolism

Glycosphingolipid biosynthesis - ganglio series

Glycosphingolipid biosynthesis - globo series

Linoleic acid metabolism

N-Glycan biosynthesis

Porphyrin and chlorophyll metabolism

Proteasome

Pyrimidine metabolism

Renin-angiotensin system

Retinol metabolism

Asthma

Biosynthesis of unsaturated fatty acids

Butanoate metabolism

Cardiac muscle contraction

Cysteine and methionine metabolism

DNA replication

Fructose and mannose metabolism

Galactose metabolism

Glycosphingolipid biosynthesis - lacto and neolacto series

Homologous recombination

Keratan sulfate biosynthesis

Limonene and pinene degradation

O-Glycan biosynthesis

Olfactory transduction

Pentose phosphate pathway

Starch and sucrose metabolism

Taste transduction

Valine

alpha-Linolenic acid metabolism

leucine and isoleucine degradation

Androgen and estrogen metabolism

Base excision repair

Folate biosynthesis

Glycine

Glycosaminoglycan degradation

Glyoxylate and dicarboxylate metabolism

Histidine metabolism

Nicotinate and nicotinamide metabolism

Nucleotide excision repair

One carbon pool by folate

Other glycan degradation

Propanoate metabolism

Riboflavin metabolism

Steroid biosynthesis

Terpenoid backbone biosynthesis

serine and threonine metabolism

Ascorbate and aldarate metabolism

Basal transcription factors

C21-Steroid hormone metabolism

Drug metabolism - other enzymes

Fatty acid metabolism

Lysine degradation

Methane metabolism

Mismatch repair

Pentose and glucuronate interconversions

Primary bile acid biosynthesis

SNARE interactions in vesicular transport

Selenoamino acid metabolism

Taurine and hypotaurine metabolism

Ubiquinone and other terpenoid-quinone biosynthesis

beta-Alanine metabolism

None

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