Expression Plasmids

cDNA Clones

Expression Plasmids

Human

P53

PTCH1

TCF7L2

TCF7

GLI1

APC

FZD3

STK36

WNT8A

DISHEVELLED 3

FRIZZLED 2

FRIZZLED 6

FRIZZLED 7

FRIZZLED 8

FRIZZLED HOMOLOG 1

GLI3

HHIP

LEF1

PTCH2

SUPPRESSOR OF FUSED

TCF7L1

WNT10B

WNT2B

WNT5A

TurboGFP

Myc-DDK

pCMV6-Entry

No

LentiORF

TrueORF Gold, TrueORF

TrueORF

Druggable Genome

Transcription Factors

ES Cell Differentiation/IPS

Transmembrane

Stem cell - Pluripotency

Cancer stem cells

Adult stem cells

Secreted Protein

GPCR

Embryonic stem cells

Stem cell relevant signaling - DSL/Notch pathway

Stem cell relevant signaling - Wnt Signaling pathway

Induced pluripotent stem cells

Protein Kinase

Metabolic pathways

Pathways in cancer

MAPK signaling pathway

Neuroactive ligand-receptor interaction

Olfactory transduction

Calcium signaling pathway

Regulation of actin cytoskeleton

Focal adhesion

Cytokine-cytokine receptor interaction

Endocytosis

Alzheimer's disease

Purine metabolism

Ubiquitin mediated proteolysis

Huntington's disease

Chemokine signaling pathway

Progesterone-mediated oocyte maturation

Axon guidance

Wnt signaling pathway

Tight junction

Vascular smooth muscle contraction

Leukocyte transendothelial migration

Jak-STAT signaling pathway

Natural killer cell mediated cytotoxicity

Cell adhesion molecules (CAMs)

Dilated cardiomyopathy

Adherens junction

Neurotrophin signaling pathway

Cell cycle

Insulin signaling pathway

Oocyte meiosis

Arrhythmogenic right ventricular cardiomyopathy (ARVC)

Apoptosis

T cell receptor signaling pathway

Prostate cancer

Hypertrophic cardiomyopathy (HCM)

GnRH signaling pathway

Type II diabetes mellitus

Viral myocarditis

Fc gamma R-mediated phagocytosis

Lysosome

p53 signaling pathway

ErbB signaling pathway

Gap junction

Small cell lung cancer

Long-term potentiation

Colorectal cancer

ECM-receptor interaction

Pyrimidine metabolism

VEGF signaling pathway

Melanogenesis

Pancreatic cancer

Toll-like receptor signaling pathway

Parkinson's disease

Hematopoietic cell lineage

Long-term depression

Renal cell carcinoma

Melanoma

B cell receptor signaling pathway

Oxidative phosphorylation

PPAR signaling pathway

Acute myeloid leukemia

Chronic myeloid leukemia

Spliceosome

mTOR signaling pathway

Endometrial cancer

Amyotrophic lateral sclerosis (ALS)

Cardiac muscle contraction

Phosphatidylinositol signaling system

Adipocytokine signaling pathway

Bladder cancer

Glycerophospholipid metabolism

NOD-like receptor signaling pathway

ABC transporters

Glioma

Drug metabolism - cytochrome P450

RIG-I-like receptor signaling pathway

Non-small cell lung cancer

Systemic lupus erythematosus

Fc epsilon RI signaling pathway

Metabolism of xenobiotics by cytochrome P450

RNA degradation

TGF-beta signaling pathway

Epithelial cell signaling in Helicobacter pylori infection

Inositol phosphate metabolism

Taste transduction

Retinol metabolism

Drug metabolism - other enzymes

Cytosolic DNA-sensing pathway

Glycolysis / Gluconeogenesis

Basal cell carcinoma

Complement and coagulation cascades

N-Glycan biosynthesis

Vibrio cholerae infection

Arachidonic acid metabolism

Glutathione metabolism

Lysine degradation

Ribosome

Starch and sucrose metabolism

Arginine and proline metabolism

Amino sugar and nucleotide sugar metabolism

Pathogenic Escherichia coli infection

Tyrosine metabolism

Antigen processing and presentation

Hedgehog signaling pathway

Notch signaling pathway

Base excision repair

Pyruvate metabolism

Fatty acid metabolism

Glycerolipid metabolism

Thyroid cancer

Nucleotide excision repair

Prion diseases

Sphingolipid metabolism

Cysteine and methionine metabolism

Primary immunodeficiency

Homologous recombination

Autoimmune thyroid disease

Porphyrin and chlorophyll metabolism

Valine

Mismatch repair

Type I diabetes mellitus

Citrate cycle (TCA cycle)

DNA replication

Basal transcription factors

Tryptophan metabolism

Proteasome

RNA polymerase

Aminoacyl-tRNA biosynthesis

leucine and isoleucine degradation

Androgen and estrogen metabolism

Glycosphingolipid biosynthesis - lacto and neolacto series

Pentose and glucuronate interconversions

Phenylalanine metabolism

Propanoate metabolism

Histidine metabolism

Allograft rejection

Fructose and mannose metabolism

Dorso-ventral axis formation

Graft-versus-host disease

Nitrogen metabolism

Selenoamino acid metabolism

Ether lipid metabolism

Glycine

Maturity onset diabetes of the young

Steroid biosynthesis

serine and threonine metabolism

SNARE interactions in vesicular transport

Ascorbate and aldarate metabolism

Galactose metabolism

Glycosaminoglycan degradation

Keratan sulfate biosynthesis

Pantothenate and CoA biosynthesis

Alanine

Glycosylphosphatidylinositol(GPI)-anchor biosynthesis

One carbon pool by folate

aspartate and glutamate metabolism

Pentose phosphate pathway

Nicotinate and nicotinamide metabolism

Chondroitin sulfate biosynthesis

Linoleic acid metabolism

Non-homologous end-joining

Regulation of autophagy

Riboflavin metabolism

Biosynthesis of unsaturated fatty acids

Cyanoamino acid metabolism

Butanoate metabolism

Heparan sulfate biosynthesis

Protein export

Circadian rhythm - mammal

Glycosphingolipid biosynthesis - ganglio series

Other glycan degradation

Primary bile acid biosynthesis

beta-Alanine metabolism

Asthma

Limonene and pinene degradation

O-Glycan biosynthesis

Taurine and hypotaurine metabolism

alpha-Linolenic acid metabolism

Glycosphingolipid biosynthesis - globo series

Glyoxylate and dicarboxylate metabolism

Renin-angiotensin system

Terpenoid backbone biosynthesis

Lysine biosynthesis

Thiamine metabolism

leucine and isoleucine biosynthesis

Fatty acid biosynthesis

O-Mannosyl glycan biosynthesis

Biotin metabolism

Folate biosynthesis

Sulfur metabolism

Lipoic acid metabolism

Methane metabolism

Phenylalanine

Synthesis and degradation of ketone bodies

tyrosine and tryptophan biosynthesis

Caffeine metabolism

D-Glutamine and D-glutamate metabolism

Fatty acid elongation in mitochondria

C21-Steroid hormone metabolism

Vitamin B6 metabolism

Ubiquinone and other terpenoid-quinone biosynthesis

Neomycin

1

Yes

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