Mutant ORF Clones

cDNA Clones

Mutant ORF Clones

Human

BRCA1

Myc-DDK

pCMV6-Entry

Yes

TrueORF

Druggable Genome

Transcription Factors

Pathways in cancer

Endometrial cancer

Prostate cancer

Melanoma

Colorectal cancer

Glioma

Non-small cell lung cancer

Bladder cancer

MAPK signaling pathway

Thyroid cancer

Pancreatic cancer

Chronic myeloid leukemia

Neurotrophin signaling pathway

Small cell lung cancer

Basal cell carcinoma

Wnt signaling pathway

Apoptosis

Cell cycle

p53 signaling pathway

Amyotrophic lateral sclerosis (ALS)

Huntington's disease

ErbB signaling pathway

Regulation of actin cytoskeleton

Focal adhesion

Renal cell carcinoma

Chemokine signaling pathway

Acute myeloid leukemia

Insulin signaling pathway

Natural killer cell mediated cytotoxicity

Gap junction

GnRH signaling pathway

B cell receptor signaling pathway

Fc epsilon RI signaling pathway

Melanogenesis

T cell receptor signaling pathway

Tight junction

VEGF signaling pathway

Long-term depression

Long-term potentiation

Axon guidance

Progesterone-mediated oocyte maturation

Endocytosis

Adherens junction

Dorso-ventral axis formation

Cytokine-cytokine receptor interaction

Epithelial cell signaling in Helicobacter pylori infection

mTOR signaling pathway

Leukocyte transendothelial migration

Calcium signaling pathway

Fc gamma R-mediated phagocytosis

Toll-like receptor signaling pathway

Arrhythmogenic right ventricular cardiomyopathy (ARVC)

Jak-STAT signaling pathway

Pathogenic Escherichia coli infection

Vascular smooth muscle contraction

Inositol phosphate metabolism

Phosphatidylinositol signaling system

Type II diabetes mellitus

Citrate cycle (TCA cycle)

Glutathione metabolism

Metabolic pathways

TGF-beta signaling pathway

Adipocytokine signaling pathway

Mismatch repair

Oocyte meiosis

Prion diseases

Primary immunodeficiency

Hematopoietic cell lineage

Homologous recombination

Notch signaling pathway

PPAR signaling pathway

Ubiquitin mediated proteolysis

Neomycin

1

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