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MLH1 Mutant (W712X), Myc-DDK-tagged ORF clone of Homo sapiens mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli) (MLH1), transcript variant 1 as transfection-ready DNA
| Mutation | W712X |
| Tag | Myc-DDK |
| Vector | pCMV6-Entry |
- TrueORF®
Mutant ORF Clones
MLH1 Mutant (K443Q), Myc-DDK-tagged ORF clone of Homo sapiens mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli) (MLH1), transcript variant 1 as transfection-ready DNA
| Mutation | K443Q |
| Tag | Myc-DDK |
| Vector | pCMV6-Entry |
- TrueORF®
ERCC2 Mutant (Y542C), Myc-DDK-tagged ORF clone of Homo sapiens excision repair cross-complementing rodent repair deficiency, complementation group 2 (ERCC2), transcript variant 1 as transfection-ready DNA
| Mutation | Y542C |
| Tag | Myc-DDK |
| Vector | pCMV6-Entry |
- TrueORF®
MLH1 Mutant (S46I), Myc-DDK-tagged ORF clone of Homo sapiens mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli) (MLH1), transcript variant 1 as transfection-ready DNA
| Mutation | S46I |
| Tag | Myc-DDK |
| Vector | pCMV6-Entry |
- TrueORF®
BRCA1 Mutant (D67E), Myc-DDK-tagged ORF clone of Homo sapiens breast Cancer, early onset (BRCA1), transcript variant 1 as transfection-ready DNA
| Mutation | D67E |
| Tag | Myc-DDK |
| Vector | pCMV6-Entry |
- TrueORF®
GCK Mutant (G175v), Myc-DDK-tagged ORF clone of Homo sapiens glucokinase (hexokinase 4) (GCK), transcript variant 1 as transfection-ready DNA
| Mutation | G175v |
| Tag | Myc-DDK |
| Vector | pCMV6-Entry |
- TrueORF®
MSH2 Mutant (C333R), Myc-DDK-tagged ORF clone of Homo sapiens mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli) (MSH2) as transfection-ready DNA
| Mutation | C333R |
| Tag | Myc-DDK |
| Vector | pCMV6-Entry |
- TrueORF®
PTEN Mutant (F241fs*15), Myc-DDK-tagged ORF clone of Homo sapiens phosphatase and tensin homolog (PTEN) as transfection-ready DNA
| Mutation | F241fs*15 |
| Tag | Myc-DDK |
| Vector | pCMV6-Entry |
- TrueORF®
MEN1 Mutant (Y312X), Myc-DDK-tagged ORF clone of Homo sapiens multiple endocrine neoplasia I (MEN1), transcript variant 2 as transfection-ready DNA
| Mutation | Y312X |
| Tag | Myc-DDK |
| Vector | pCMV6-Entry |
- TrueORF®
MEN1 Mutant (E45A), Myc-DDK-tagged ORF clone of Homo sapiens multiple endocrine neoplasia I (MEN1), transcript variant 2 as transfection-ready DNA
| Mutation | E45A |
| Tag | Myc-DDK |
| Vector | pCMV6-Entry |
- TrueORF®
MLH1 Mutant (R659X), Myc-DDK-tagged ORF clone of Homo sapiens mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli) (MLH1), transcript variant 1 as transfection-ready DNA
| Mutation | R659X |
| Tag | Myc-DDK |
| Vector | pCMV6-Entry |
- TrueORF®
AXIN2 Mutant (R659W), Myc-DDK-tagged ORF clone of Homo sapiens axin 2 (AXIN2) as transfection-ready DNA
| Mutation | R659W |
| Tag | Myc-DDK |
| Vector | pCMV6-Entry |
- TrueORF®
BUB1B Mutant (Q349R), Myc-DDK-tagged ORF clone of Homo sapiens budding uninhibited by benzimidazoles 1 homolog beta (yeast) (BUB1B) as transfection-ready DNA
| Mutation | Q349R |
| Tag | Myc-DDK |
| Vector | pCMV6-Entry |
- TrueORF®
GNAS Mutant (R265H), Myc-DDK-tagged ORF clone of Homo sapiens GNAS complex locus (GNAS), transcript variant 1 as transfection-ready DNA
| Mutation | R265H |
| Tag | Myc-DDK |
| Vector | pCMV6-Entry |
- TrueORF®
活动过滤器
优化搜索结果
Species
Target Symbol
- BRCA1 (388)
- BTK (291)
- BRCA2 (273)
- GCK (249)
- TSC2 (240)
- MEN1 (237)
- MLH1 (233)
- MSH2 (212)
- RET (179)
- NOTCH3 (156)
- P53 (119)
- NF2 (87)
- MSH6 (83)
- STK11 (78)
- PI 3 KINASE CATALYTIC SUBUNIT ALPHA (66)
- WT1 (62)
- FH (60)
- FGFR1 (53)
- GNAS (47)
- PTEN (43)
- EGFR (39)
- ERCC2 (37)
- BRAF (34)
- FLT4 (33)
- CTNNB1 (32)
- TERT (30)
- CBL (24)
- CDKN2A (23)
- KRAS (21)
- PRKCG (21)
- HRAS (18)
- RAF1 (18)
- NRAS (17)
- ROR2 (16)
- BETA CATENIN (14)
- ALK (13)
- MAP2K2 (12)
- GPC3 (11)
- CDKN1C (10)
- GRK1 (10)
- MYCN (10)
- AMHR2 (9)
- B RAF (9)
- BUB1B (9)
- MET (9)
- CDH1 (8)
- LPAR6 (7)
- MAP2K1 (7)
- ACTIVIN RECEPTOR TYPE IA (6)
- GATA1 (6)
- MERTK (6)
- P21 RAS (6)
- AXIN1 (5)
- CBLB (5)
- ISOCITRATE DEHYDROGENASE (5)
- RB1 (5)
- ZAP70 (5)
- CDK4 (4)
- EPHX1 (4)
- LKB1 (4)
- PAK3 (4)
- STAT1 (4)
- TYK2 (4)
- XRCC1 (4)
- ACVR1 (3)
- AURKA (3)
- AXIN2 (3)
- CDKN1B (3)
- DDR2 (3)
- GRK4 (3)
- IDH2 (3)
- MAF (3)
- MEK1 (3)
- SERPIND1 (3)
- AKT1 (2)
- MPL (2)
- MYBL2 (2)
- MYC (2)
- TEK (2)
- TPOR (2)
- AURKC (1)
- BCL2 (1)
- BUBR1 (1)
- CDK7 (1)
- CSF1R (1)
- EPHA2 (1)
- ERBB2 (1)
- FGFR4 (1)
- FLT3 (1)
- FRK (1)
- GRK5 (1)
- HIF-1 ALPHA (1)
- HIF1A (1)
- HOXB13 (1)
- INTEGRIN LINKED KINASE (1)
- IRAK1 (1)
- JAG2 (1)
- LTK (1)
- LYN (1)
- MASTL (1)
Tags
Mutants
Brands
Families
- Druggable Genome (3798)
- Transcription Factors (951)
- Protein Kinase (914)
- Stem cell - Pluripotency (438)
- Transmembrane (386)
- ES Cell Differentiation/IPS (123)
- Secreted Protein (86)
- Adult stem cells (45)
- Phosphatase (43)
- Stem cell relevant signaling - JAK/STAT signaling pathway (41)
- Cancer stem cells (39)
- GPCR (7)
- Stem cell relevant signaling - Wnt Signaling pathway (7)
- Induced pluripotent stem cells (5)
- Protease (4)
- Embryonic stem cells (2)
- Stem cell relevant signaling - TGFb/BMP signaling pathway (2)
Pathways
- Pathways in cancer (1679)
- Colorectal cancer (913)
- Insulin signaling pathway (732)
- Endometrial cancer (714)
- Pancreatic cancer (630)
- Mismatch repair (528)
- Prostate cancer (525)
- Melanoma (518)
- Thyroid cancer (481)
- Glioma (469)
- B cell receptor signaling pathway (463)
- Fc epsilon RI signaling pathway (463)
- mTOR signaling pathway (436)
- p53 signaling pathway (430)
- Non-small cell lung cancer (428)
- Ubiquitin mediated proteolysis (417)
- Chronic myeloid leukemia (401)
- MAPK signaling pathway (382)
- Focal adhesion (362)
- Bladder cancer (348)
- Neurotrophin signaling pathway (335)
- Metabolic pathways (318)
- Type II diabetes mellitus (316)
- ErbB signaling pathway (314)
- Regulation of actin cytoskeleton (309)
- Endocytosis (296)
- Primary immunodeficiency (296)
- Renal cell carcinoma (289)
- Homologous recombination (273)
- Amino sugar and nucleotide sugar metabolism (249)
- Galactose metabolism (249)
- Glycolysis / Gluconeogenesis (249)
- Maturity onset diabetes of the young (249)
- Starch and sucrose metabolism (249)
- Small cell lung cancer (247)
- Natural killer cell mediated cytotoxicity (238)
- Dorso-ventral axis formation (226)
- Chemokine signaling pathway (221)
- Acute myeloid leukemia (217)
- Melanogenesis (216)
- Long-term depression (214)
- T cell receptor signaling pathway (213)
- Gap junction (209)
- Wnt signaling pathway (196)
- VEGF signaling pathway (192)
- Apoptosis (190)
- GnRH signaling pathway (188)
- Cell cycle (179)
- Tight junction (179)
- Basal cell carcinoma (173)
- Long-term potentiation (166)
- Progesterone-mediated oocyte maturation (161)
- Notch signaling pathway (157)
- Adherens junction (156)
- Vascular smooth muscle contraction (152)
- Leukocyte transendothelial migration (134)
- Phosphatidylinositol signaling system (132)
- Amyotrophic lateral sclerosis (ALS) (120)
- Fc gamma R-mediated phagocytosis (119)
- Huntington's disease (119)
- Jak-STAT signaling pathway (112)
- Inositol phosphate metabolism (111)
- Calcium signaling pathway (108)
- Cytokine-cytokine receptor interaction (105)
- Toll-like receptor signaling pathway (96)
- Adipocytokine signaling pathway (84)
- Axon guidance (76)
- Citrate cycle (TCA cycle) (68)
- Vibrio cholerae infection (68)
- Pathogenic Escherichia coli infection (54)
- Epithelial cell signaling in Helicobacter pylori infection (49)
- Dilated cardiomyopathy (47)
- Taste transduction (47)
- Arrhythmogenic right ventricular cardiomyopathy (ARVC) (46)
- Nucleotide excision repair (38)
- Prion diseases (22)
- TGF-beta signaling pathway (20)
- Oocyte meiosis (13)
- Cell adhesion molecules (CAMs) (8)
- Glutathione metabolism (8)
- Neuroactive ligand-receptor interaction (7)
- Base excision repair (4)
- Metabolism of xenobiotics by cytochrome P450 (4)
- Complement and coagulation cascades (3)
- Hematopoietic cell lineage (2)
- PPAR signaling pathway (1)
