cDNA Clones

cDNA Clones

Expression Plasmids

Mutant ORF Clones

Human

GNAS

CTNNB1

KRAS

PRKACB

PRKCG

RAF1

TCF7L2

HRAS

NRAS

BETA CATENIN

MITF

CAMK2B

MAP2K2

G PROTEIN ALPHA INHIBITOR 2

G PROTEIN ALPHA S

CAMK2G

P21 RAS

TCF7

CAMK2D

PHOSPHOLIPASE C BETA 2

MAP2K1

ADCY4

CD117

ENDOTHELIN B RECEPTOR

LEF1

MEK1

ADCY5

ADCY6

ADCY7

CREB1

FRIZZLED 6

FZD3

PHOSPHOLIPASE C BETA 3

PHOSPHOLIPASE C BETA 4

ACTH

ADENYLATE CYCLASE 1

CAMK2A

ERK1

ERK2

G PROTEIN ALPHA INHIBITOR 1

G0 PROTEIN ALPHA

KAT3A / CBP

PHOSPHOLIPASE C BETA 1

WNT5A

ADCY9

CALMODULIN

DISHEVELLED 3

DVL1

ENDOTHELIN 1

EP300

FRIZZLED 2

FRIZZLED 7

FRIZZLED 8

FRIZZLED HOMOLOG 1

GSK3 BETA

PKC ALPHA

PKC BETA 1

PRKACA

SCF

TCF7L1

WNT10B

ADCY2

ADCY3

ADCY8

BMP2

CALM1

CALM3

DISHEVELLED 2

FRIZZLED 10

FRIZZLED 4

FRIZZLED 5

FRIZZLED 9

GNAI3

GNAQ

MC1 RECEPTOR

MEK2

PKC GAMMA

PRKACG

PRKX

TRP1

WNT1

WNT3

WNT3A

WNT4

WNT7A

Myc-DDK

TurboGFP

DDK-His

pCMV6-Entry

pCMV6-AC-GFP

pCMV6-XL5-DDK-His

No

Yes

TrueORF

LentiORF

TrueClone

TrueORF Gold, TrueORF

Druggable Genome

Protein Kinase

Transcription Factors

ES Cell Differentiation/IPS

Secreted Protein

Transmembrane

GPCR

Adult stem cells

Cancer stem cells

Stem cell relevant signaling - Wnt Signaling pathway

Embryonic stem cells

Induced pluripotent stem cells

Stem cell - Pluripotency

Stem cell relevant signaling - TGFb/BMP signaling pathway

Pathways in cancer

Metabolic pathways

MAPK signaling pathway

Colorectal cancer

Insulin signaling pathway

Focal adhesion

Endometrial cancer

Regulation of actin cytoskeleton

Pancreatic cancer

Cytokine-cytokine receptor interaction

Neuroactive ligand-receptor interaction

Prostate cancer

Calcium signaling pathway

Ubiquitin mediated proteolysis

Melanoma

Neurotrophin signaling pathway

Chemokine signaling pathway

p53 signaling pathway

B cell receptor signaling pathway

Glioma

Fc epsilon RI signaling pathway

Endocytosis

ErbB signaling pathway

Wnt signaling pathway

Chronic myeloid leukemia

Progesterone-mediated oocyte maturation

Non-small cell lung cancer

Thyroid cancer

Type II diabetes mellitus

mTOR signaling pathway

Mismatch repair

Natural killer cell mediated cytotoxicity

T cell receptor signaling pathway

Apoptosis

Jak-STAT signaling pathway

Bladder cancer

Cell cycle

Renal cell carcinoma

Small cell lung cancer

GnRH signaling pathway

Vascular smooth muscle contraction

Gap junction

Adherens junction

Melanogenesis

VEGF signaling pathway

Axon guidance

Long-term depression

Leukocyte transendothelial migration

Tight junction

Long-term potentiation

Acute myeloid leukemia

Primary immunodeficiency

Toll-like receptor signaling pathway

Glycolysis / Gluconeogenesis

Alzheimer's disease

Huntington's disease

Purine metabolism

Dilated cardiomyopathy

Fc gamma R-mediated phagocytosis

Oocyte meiosis

Phosphatidylinositol signaling system

Homologous recombination

Amyotrophic lateral sclerosis (ALS)

Arrhythmogenic right ventricular cardiomyopathy (ARVC)

Starch and sucrose metabolism

Basal cell carcinoma

Galactose metabolism

Maturity onset diabetes of the young

Amino sugar and nucleotide sugar metabolism

Adipocytokine signaling pathway

Hematopoietic cell lineage

Dorso-ventral axis formation

Cell adhesion molecules (CAMs)

Hypertrophic cardiomyopathy (HCM)

Inositol phosphate metabolism

Olfactory transduction

Notch signaling pathway

ECM-receptor interaction

Lysosome

TGF-beta signaling pathway

NOD-like receptor signaling pathway

PPAR signaling pathway

Epithelial cell signaling in Helicobacter pylori infection

Complement and coagulation cascades

Taste transduction

Pathogenic Escherichia coli infection

Viral myocarditis

Cardiac muscle contraction

RIG-I-like receptor signaling pathway

ABC transporters

Vibrio cholerae infection

Pyrimidine metabolism

Drug metabolism - cytochrome P450

Nucleotide excision repair

Hedgehog signaling pathway

Glycerophospholipid metabolism

Metabolism of xenobiotics by cytochrome P450

Arachidonic acid metabolism

Cytosolic DNA-sensing pathway

Retinol metabolism

Base excision repair

Citrate cycle (TCA cycle)

Prion diseases

Parkinson's disease

Arginine and proline metabolism

Tyrosine metabolism

Valine

Drug metabolism - other enzymes

Glycerolipid metabolism

Lysine degradation

Antigen processing and presentation

Fatty acid metabolism

leucine and isoleucine degradation

Cysteine and methionine metabolism

Systemic lupus erythematosus

Pyruvate metabolism

Autoimmune thyroid disease

Glutathione metabolism

Histidine metabolism

Sphingolipid metabolism

Tryptophan metabolism

Type I diabetes mellitus

Fructose and mannose metabolism

SNARE interactions in vesicular transport

Propanoate metabolism

Proteasome

Nitrogen metabolism

Phenylalanine metabolism

Butanoate metabolism

Linoleic acid metabolism

Oxidative phosphorylation

Pentose phosphate pathway

Allograft rejection

Androgen and estrogen metabolism

Aminoacyl-tRNA biosynthesis

Steroid biosynthesis

Alanine

aspartate and glutamate metabolism

DNA replication

Riboflavin metabolism

Non-homologous end-joining

Regulation of autophagy

Ether lipid metabolism

Selenoamino acid metabolism

Spliceosome

Porphyrin and chlorophyll metabolism

Renin-angiotensin system

Circadian rhythm - mammal

Graft-versus-host disease

Glycosaminoglycan degradation

beta-Alanine metabolism

Other glycan degradation

Glycine

Primary bile acid biosynthesis

serine and threonine metabolism

N-Glycan biosynthesis

Pantothenate and CoA biosynthesis

Ribosome

leucine and isoleucine biosynthesis

Terpenoid backbone biosynthesis

Asthma

alpha-Linolenic acid metabolism

Basal transcription factors

C21-Steroid hormone metabolism

One carbon pool by folate

Pentose and glucuronate interconversions

RNA degradation

Ascorbate and aldarate metabolism

Folate biosynthesis

Limonene and pinene degradation

Nicotinate and nicotinamide metabolism

Protein export

Synthesis and degradation of ketone bodies

Fatty acid biosynthesis

Glyoxylate and dicarboxylate metabolism

Glycosphingolipid biosynthesis - ganglio series

Thiamine metabolism

Biosynthesis of unsaturated fatty acids

Glycosphingolipid biosynthesis - globo series

Taurine and hypotaurine metabolism

Biotin metabolism

Glycosphingolipid biosynthesis - lacto and neolacto series

Phenylalanine

tyrosine and tryptophan biosynthesis

Caffeine metabolism

Heparan sulfate biosynthesis

Ubiquinone and other terpenoid-quinone biosynthesis

Fatty acid elongation in mitochondria

Sulfur metabolism

Glycosylphosphatidylinositol(GPI)-anchor biosynthesis

Methane metabolism

Chondroitin sulfate biosynthesis

RNA polymerase

Lysine biosynthesis

O-Glycan biosynthesis

Vitamin B6 metabolism

D-Arginine and D-ornithine metabolism

D-Glutamine and D-glutamate metabolism

Keratan sulfate biosynthesis

Neomycin

None

1

Yes

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