cDNA Clones

cDNA Clones

Expression Plasmids

Human

P21 RAS

TCF7L2

AKT1

AKT3

AXIN 1

BETA CATENIN

CASPASE 9

CTNNA3

EGFR

ERK2

FOXO3

GRB2

GSK3 BETA

HER2

INTEGRIN LINKED KINASE

KRAS

P53

PDPK1

PI 3 KINASE P55 GAMMA

PI 3 KINASE P85 ALPHA

PIK3R5

A RAF

AKT2

ALPHA 1 CATENIN

B RAF

BAD

C-MYC

CTNNA2

CYCLIN D1

E CADHERIN

EGF

ELK1

ERK1

LEF1

MEK1

MEK2

MLH1

NRAS

PI 3 KINASE CATALYTIC SUBUNIT ALPHA

PI 3 KINASE CATALYTIC SUBUNIT GAMMA

PI 3 KINASE P85 BETA

PIK3CB

PIK3CD

PTEN

RAF1

SOS1

TCF7

Plasmids

mGFP

pCMV6-Entry

pCMV6-AC-GFP

pLenti-C-Myc-DDK-P2A-Puro

pLenti-C-mGFP-P2A-Puro

pCMV6-AC-Myc-DDK

pLenti-C-Myc-DDK

pLenti-C-mGFP

pCMV6-XL5

pCMV6-XL4

pCMV6-AN-Myc-DDK

pCMV6-AC

pCMV6-XL5-DDK-His

pCMV6-XL6

No

LentiORF

Druggable Genome

Protein Kinase

ES Cell Differentiation/IPS

Transcription Factors

Stem cell - Pluripotency

Transmembrane

Adult stem cells

Stem cell relevant signaling - JAK/STAT signaling pathway

Stem cell relevant signaling - Wnt Signaling pathway

Cancer stem cells

Embryonic stem cells

Induced pluripotent stem cells

Protease

Secreted Protein

Phosphatase

Stem cell relevant signaling - DSL/Notch pathway

Stem cell relevant signaling - TGFb/BMP signaling pathway

Metabolic pathways

Pathways in cancer

MAPK signaling pathway

Cytokine-cytokine receptor interaction

Neuroactive ligand-receptor interaction

Regulation of actin cytoskeleton

Focal adhesion

Chemokine signaling pathway

Neurotrophin signaling pathway

Endocytosis

Wnt signaling pathway

Jak-STAT signaling pathway

Calcium signaling pathway

Natural killer cell mediated cytotoxicity

Insulin signaling pathway

Leukocyte transendothelial migration

T cell receptor signaling pathway

Toll-like receptor signaling pathway

Ubiquitin mediated proteolysis

Cell adhesion molecules (CAMs)

Axon guidance

Alzheimer's disease

ErbB signaling pathway

Progesterone-mediated oocyte maturation

Prostate cancer

Melanogenesis

Huntington's disease

Oocyte meiosis

Cell cycle

Apoptosis

Tight junction

Colorectal cancer

GnRH signaling pathway

Pancreatic cancer

B cell receptor signaling pathway

Chronic myeloid leukemia

Fc gamma R-mediated phagocytosis

Vascular smooth muscle contraction

Purine metabolism

VEGF signaling pathway

Fc epsilon RI signaling pathway

Melanoma

Adherens junction

Hematopoietic cell lineage

TGF-beta signaling pathway

Gap junction

Small cell lung cancer

Renal cell carcinoma

Lysosome

RIG-I-like receptor signaling pathway

Glioma

Adipocytokine signaling pathway

NOD-like receptor signaling pathway

Parkinson's disease

Acute myeloid leukemia

p53 signaling pathway

Long-term potentiation

Dilated cardiomyopathy

Non-small cell lung cancer

Antigen processing and presentation

Spliceosome

Endometrial cancer

Hypertrophic cardiomyopathy (HCM)

Long-term depression

Amyotrophic lateral sclerosis (ALS)

Epithelial cell signaling in Helicobacter pylori infection

Systemic lupus erythematosus

Hedgehog signaling pathway

mTOR signaling pathway

Arrhythmogenic right ventricular cardiomyopathy (ARVC)

PPAR signaling pathway

Basal cell carcinoma

Bladder cancer

Type II diabetes mellitus

Oxidative phosphorylation

Viral myocarditis

Complement and coagulation cascades

Cytosolic DNA-sensing pathway

Pathogenic Escherichia coli infection

ECM-receptor interaction

Glycolysis / Gluconeogenesis

Arginine and proline metabolism

Phosphatidylinositol signaling system

Vibrio cholerae infection

Ribosome

Glycerophospholipid metabolism

Autoimmune thyroid disease

Metabolism of xenobiotics by cytochrome P450

Retinol metabolism

Thyroid cancer

Olfactory transduction

Cardiac muscle contraction

Pyrimidine metabolism

Drug metabolism - cytochrome P450

Primary immunodeficiency

Valine

Notch signaling pathway

Type I diabetes mellitus

Arachidonic acid metabolism

Lysine degradation

Nucleotide excision repair

Prion diseases

Regulation of autophagy

Sphingolipid metabolism

Tryptophan metabolism

Tyrosine metabolism

leucine and isoleucine degradation

Starch and sucrose metabolism

Amino sugar and nucleotide sugar metabolism

Drug metabolism - other enzymes

Maturity onset diabetes of the young

Glutathione metabolism

Graft-versus-host disease

Inositol phosphate metabolism

N-Glycan biosynthesis

Pyruvate metabolism

RNA degradation

Allograft rejection

ABC transporters

Citrate cycle (TCA cycle)

Proteasome

Taste transduction

Cysteine and methionine metabolism

Fructose and mannose metabolism

Androgen and estrogen metabolism

Glycerolipid metabolism

Ether lipid metabolism

Fatty acid metabolism

Alanine

Dorso-ventral axis formation

aspartate and glutamate metabolism

Base excision repair

Galactose metabolism

Propanoate metabolism

SNARE interactions in vesicular transport

Glycine

Nitrogen metabolism

serine and threonine metabolism

Linoleic acid metabolism

Asthma

Butanoate metabolism

DNA replication

Glycosaminoglycan degradation

Glycosphingolipid biosynthesis - lacto and neolacto series

Homologous recombination

Porphyrin and chlorophyll metabolism

Histidine metabolism

O-Glycan biosynthesis

Pentose phosphate pathway

Phenylalanine metabolism

Biosynthesis of unsaturated fatty acids

Renin-angiotensin system

Aminoacyl-tRNA biosynthesis

beta-Alanine metabolism

Circadian rhythm - mammal

Mismatch repair

Heparan sulfate biosynthesis

Nicotinate and nicotinamide metabolism

Non-homologous end-joining

One carbon pool by folate

Pentose and glucuronate interconversions

Primary bile acid biosynthesis

alpha-Linolenic acid metabolism

Ascorbate and aldarate metabolism

Glycosphingolipid biosynthesis - ganglio series

Glycosphingolipid biosynthesis - globo series

Other glycan degradation

Riboflavin metabolism

Steroid biosynthesis

C21-Steroid hormone metabolism

Selenoamino acid metabolism

Terpenoid backbone biosynthesis

Basal transcription factors

Glyoxylate and dicarboxylate metabolism

Keratan sulfate biosynthesis

Limonene and pinene degradation

RNA polymerase

Folate biosynthesis

Glycosylphosphatidylinositol(GPI)-anchor biosynthesis

Protein export

Methane metabolism

Pantothenate and CoA biosynthesis

Sulfur metabolism

Chondroitin sulfate biosynthesis

Fatty acid elongation in mitochondria

Taurine and hypotaurine metabolism

Thiamine metabolism

leucine and isoleucine biosynthesis

Cyanoamino acid metabolism

Caffeine metabolism

Synthesis and degradation of ketone bodies

Vitamin B6 metabolism

D-Glutamine and D-glutamate metabolism

Ubiquinone and other terpenoid-quinone biosynthesis

Phenylalanine

tyrosine and tryptophan biosynthesis

Biotin metabolism

D-Arginine and D-ornithine metabolism

Fatty acid biosynthesis

Lipoic acid metabolism

Lysine biosynthesis

O-Mannosyl glycan biosynthesis

None

1

Yes

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