Products

cDNA Clones

Proteins

Expression Plasmids

Recombinant Proteins

CytoSections

Mutant ORF Clones

Mass Spec Standards

Mutant Proteins

Lentiviral Particles

Native Proteins

Over-expression Lysates

Mutant CytoSections

Human

Mouse

Humon

BRCA1

BTK

GLUCOKINASE

BRCA2

MENIN

TUBERIN

MLH1

MSH2

RET

P53

NOTCH3

FGFR1

NF2

BDNF

VEGFA

ALPHA 1 ANTITRYPSIN

PDE9A

WILMS TUMOR PROTEIN

CONSTITUTIVE ANDROSTANE RECEPTOR

G PROTEIN ALPHA S

LKB1

MSH6

NRG1

MU OPIOID RECEPTOR

DYSTROBREVIN ALPHA

BETA CATENIN

EGFR

HNF 4 ALPHA

PI 3 KINASE CATALYTIC SUBUNIT ALPHA

FH

CD46

HMGA1

TPM1

TGIF

PML PROTEIN

ALPHA DYSTROGLYCAN

ASPARTATE BETA HYDROXYLASE

B RAF

P38

TAU

AURORA A

ESTROGEN RELATED RECEPTOR GAMMA

APC11

CAMK2B

GM CSF RECEPTOR ALPHA

MAX

PRKAR1B

FGF1

GPR56

CAMKK2

P16INK4A

ABL2

P21 RAS

PTEN

CD59

JNK1

MITF

NEK6

FLT4

ALKALINE PHOSPHATASE

CAMK2D

CD44

TCF7L2

TMPRSS4

MID1

RAD17

S100 CALCIUM BINDING PROTEIN A13

CACNB2

CHRM2

XPD

CREM

MSF

P63

ALPHA SYNUCLEIN

APRATAXIN

CASPASE 1

PPAR GAMMA

CARDIAC TROPONIN T

CD36

DOUBLECORTIN

TRKB

AMYLOID PRECURSOR PROTEIN

ANNEXIN A2

CATHEPSIN B

EMA

OGG1

PAX2

PAX3

CTNND1

GLUCOCORTICOID RECEPTOR

HNRNPD

IKK GAMMA

KRAS

PAK4

PPP2R2B

ACRV1

NCOA4

NEUROLIGIN 4

RGS3

ALDOLASE

IHC

WB

HEK293T

HEK293

E. coli

Sf9

Insect

CHO

Baculovirus

Pichia

Plasmids

Particles

Myc-DDK

mGFP

C-Myc/DDK

Tag Free

TurboGFP

C-MYC/DDK

N-His

N-GST and C-His

C-DDK

C-His

C-DDK/His

DDK-His

C-6His

N-GST and C-HIS

N-His-ABP (Albumin-Binding Protein)

C-HIS

C-Fc

His-tag

His-Tag

C-8His

C-Human Fc

N-His-Trx

C-6×His

C-hFc

N-6His

C-Mouse Fc

C-Avi&6His

Tag-free

C-Mouse Fc and 6×His

C- 6×His

C-10His

N-HIS

C-Human Fc and 6×His

C-hFc&His

N-8His

N-His/DDK

C-Fc/His

C-HUMAN

N-GST

N-GST, C-His

N-His-PDCD1(Pro21-Val170)

N-Mouse Fc and C-6×His

C-6xHis/AVI

C-AVI-PLUS

C-DDK/10xHis

C-DDK/6xHis

C-FC

C-HIS/DDK

C-Myc-DDK

N-6His-FLAG

N-AVI

N-Avi&6His

N-DDK

N-DDK/His

N-FLAG

N-FUSION

N-Fc-FLAG

N-Flag&C-His

N-GFP

N-GST(CKM) and N-His(CKB)

N-GST/C-His

N-His-GST

N-Human Fc

N-T7

N-TRX

N-TRXA

N-hFc

N-terminal His

Tag free

pCMV6-Entry

pCMV6-AC-GFP

pLenti-C-Myc-DDK-P2A-Puro

pLenti-C-mGFP-P2A-Puro

pLenti-C-Myc-DDK

pLenti-C-mGFP

pCMV6-XL5

pCMV6-XL4

pCMV6-AC

pCMV6-XL6

pCMV6-AC-Myc-DDK

PCMV6-Neo

pCMV6-XL5-DDK-His

pCMV6-AN-Myc-DDK

pRMT-tGFP, Promoter-less GFP Reporter Vector

No

Yes

LentiORF

TrueORF

TrueClone

MVPro

CytoSections

TrueORF Gold, TrueORF

SDS PAGE

Druggable Genome

Transmembrane

WB

Transcription Factors

Secreted Protein

Protein Kinase

Protease

ES Cell Differentiation/IPS

Stem cell - Pluripotency

GPCR

Phosphatase

Ion Channels: Other

Adult stem cells

Nuclear Hormone Receptor

Embryonic stem cells

Ion Channels: Potassium

Cancer stem cells

P450

Induced pluripotent stem cells

Ion Channels: Cys-loop Receptors

Stem cell relevant signaling - JAK/STAT signaling pathway

Stem cell relevant signaling - TGFb/BMP signaling pathway

Ion Channels: Transient receptor potential

Stem cell relevant signaling - Wnt Signaling pathway

Stem cell relevant signaling - DSL/Notch pathway

Ion Channels: Glutamate Receptors

Ion Channels: Sodium

Ion Channels: ATP Receptors

Ion Channels: Calcium

Ion Channels: Cyclic nucleotide gated

ELISA

SDS-PAGE

Bioactivity

10 mM Tris-HCl

the solution can be further dialyzed against PBS (phosphate buffered saline

Flow Cyt

2 mM dithiothreitol

ELISA.
Western Blot.

e.g. Dulbecco's PBS).

Enzyme Activity

both dissolved in 9.5 M urea buffer (see above). Protofilaments and filament complexes are obtained by dialyzing the resulting polypeptide solution stepwise to a concentration of 4 M urea and then to low salt condition (50 mM NaCl

Protein standard in 1D and 2D SDS gelelectrophoresis.
Immunoassays.
Immunization.
Protocol: Reconstitution to filaments is performed by mixing equimolar amounts of keratins of type I and type II at concentrations of approx. 0.5 mg/ml

pH 7.4). For immunization purposes

Protein standard in 1D and 2D SDS gelelectrophoresis.
Immunoassays.
Immunization.
Protocol: Reconstitution to filaments is performed by mixing equimolar amounts of keratins of type I and type II at concentrations of approx. 0.5 mg/ml

pH 7.4).
For immunization purposes

pH 7.4).
For immunization purposes

Western Blot.

0.1% (w/v) insulin

10mM Tris-HCl

1mM DTT

2 mM dithiothreitol

2mM EDTA.
2. Add 4ug of recombinant thioredoxin into reaction cocktail and mix immediately.
3. Incubate at 25°C for 20 minutes.
4. Record the increase in A650nm for 15 minutes

2mM dithiothreitol

63mM sodium phosphate

Protein standard in 1D and 2D SDS gelelectrophoresis.
Immunoassays.
Immunization.
Protocol: Reconstitution to filaments: After vimentin is dissolved in 9.5M Urea buffer (see above)

Can be used as standard in a Sandwich ELISA.

FACS

Protein standard in 1D and 2D SDS gelelectrophoresis.
Immunoassays.
Immunization.
Protocol: Reconstitution to filaments: after desmin is dissolved in 9.5 M urea buffer (see above)

Protocol: Activity Assay
1. Prepare a 1 ml reaction cocktail into a suitable container: The final concentrations are 5mM Tris

Secreted

both dissolved in 9.5 M urea buffer (see above).
Protofilaments and filament complexes are obtained by dialyzing the resulting polypeptide solution stepwise to a concentration of 4 M urea and then to low salt condition (50 mM NaCl

e.g. Dulbeccos PBS).

e.g.Dulbecco's PBS).

protofilaments and filament complexes are obtained by dialyzing the resulting polypeptide solution stepwise to a concentration of 4M Urea and then to low salt condition (50mM NaCl

protofilaments and filament complexes are obtained by dialyzing the resulting polypeptide solution stepwise to a concentration of 4M urea and then to low salt condition (50 mM NaCl

the solution can be further dialyzed against PBS (Phosphate Buffered Saline

ELISA.
Suitable for use as a Control or standard in indirect trapping ELISA for quantitation of antigen in serum using a standard curve.
Immunoprecipitation.
Western blotting.

ELISA.
Western Blot.

ELISA.
Western blotting.

ELISA.

Positive control for Western blot analysis

Positive control for Western blot analysis.
Standard for ELISA.

Adermann K. Role of the prosequence of guanylin. Protein Sci. 1999 Sep; 8(9): 1850-9.
4. Lauber T

Cell culture and/or animal studies.
ELISA.
Western Blot.

Cohen MB. Proguanylin secretion and the role of negative-feedback inhibition in a villous epithelial cell line. Am J Physiol Gastrointest Liver Physiol. 2002 Sep; 283(3): G695-702.
3. Schulz A

For use as a Control or Standard in Indirect trapping ELISA for quantitation of antigen in serum using a standard curve

For use as a Control or standard in indirect trapping ELISA for quantitation of antigen in serum using a standard curve.
Immunoprecipitation.
Western blotting.

Forssmann WG

Hawkins JA

Hidaka Y

Marx UC

Marx UC. Native and recombinant proguanylin feature identical biophysical properties and are monomeric in solution. Biochemistry. 2002 Dec 10; 41(49): 14602-12.
2. Rudolph JA

Marx UC. Solution structure of human proguanylin: the role of a hormone prosequence. J Biol Chem. 2003 Jun 27; 278(26): 24118-24. Epub 2003 Apr 21.

Neudecker P

Nourse A

Rosch P

Schulz A

Shimonishi Y

Specific methodologies have not been tested using this product.

Western Blot.
Protocol: 1. Lauber T

Western Blotting.

for immunoprecipitation and for Wwestern blotting.

Metabolic pathways

Pathways in cancer

MAPK signaling pathway

Cytokine-cytokine receptor interaction

Neuroactive ligand-receptor interaction

Focal adhesion

Regulation of actin cytoskeleton

Chemokine signaling pathway

Neurotrophin signaling pathway

Insulin signaling pathway

Calcium signaling pathway

Colorectal cancer

Jak-STAT signaling pathway

Wnt signaling pathway

Prostate cancer

Pancreatic cancer

ErbB signaling pathway

T cell receptor signaling pathway

Endocytosis

Progesterone-mediated oocyte maturation

Natural killer cell mediated cytotoxicity

Cell cycle

Ubiquitin mediated proteolysis

Toll-like receptor signaling pathway

Melanoma

Apoptosis

GnRH signaling pathway

Endometrial cancer

B cell receptor signaling pathway

Axon guidance

Chronic myeloid leukemia

Fc epsilon RI signaling pathway

Glioma

Renal cell carcinoma

Oocyte meiosis

Small cell lung cancer

Adherens junction

Melanogenesis

p53 signaling pathway

Hematopoietic cell lineage

Leukocyte transendothelial migration

Gap junction

VEGF signaling pathway

Purine metabolism

Vascular smooth muscle contraction

Non-small cell lung cancer

Tight junction

Alzheimer's disease

Acute myeloid leukemia

Cell adhesion molecules (CAMs)

Dilated cardiomyopathy

Bladder cancer

Long-term potentiation

Fc gamma R-mediated phagocytosis

Huntington's disease

TGF-beta signaling pathway

Long-term depression

Adipocytokine signaling pathway

mTOR signaling pathway

NOD-like receptor signaling pathway

Hypertrophic cardiomyopathy (HCM)

Type II diabetes mellitus

Thyroid cancer

Lysosome

Amyotrophic lateral sclerosis (ALS)

Arrhythmogenic right ventricular cardiomyopathy (ARVC)

Glycolysis / Gluconeogenesis

Phosphatidylinositol signaling system

Complement and coagulation cascades

RIG-I-like receptor signaling pathway

Epithelial cell signaling in Helicobacter pylori infection

Olfactory transduction

ECM-receptor interaction

Primary immunodeficiency

PPAR signaling pathway

Basal cell carcinoma

Mismatch repair

Inositol phosphate metabolism

Pathogenic Escherichia coli infection

Viral myocarditis

Cytosolic DNA-sensing pathway

Galactose metabolism

Starch and sucrose metabolism

Amino sugar and nucleotide sugar metabolism

Antigen processing and presentation

Drug metabolism - cytochrome P450

Metabolism of xenobiotics by cytochrome P450

Hedgehog signaling pathway

Maturity onset diabetes of the young

Homologous recombination

Cardiac muscle contraction

Valine

Pyrimidine metabolism

Arginine and proline metabolism

Parkinson's disease

Retinol metabolism

Notch signaling pathway

Tyrosine metabolism

Glycerophospholipid metabolism

Arachidonic acid metabolism

Glycerolipid metabolism

Vibrio cholerae infection

Dorso-ventral axis formation

leucine and isoleucine degradation

Prion diseases

Nucleotide excision repair

Base excision repair

Autoimmune thyroid disease

ABC transporters

Taste transduction

Drug metabolism - other enzymes

Fructose and mannose metabolism

Fatty acid metabolism

Lysine degradation

Pyruvate metabolism

Systemic lupus erythematosus

Type I diabetes mellitus

Sphingolipid metabolism

Glutathione metabolism

Cysteine and methionine metabolism

Tryptophan metabolism

Butanoate metabolism

SNARE interactions in vesicular transport

Alanine

aspartate and glutamate metabolism

Regulation of autophagy

Proteasome

Androgen and estrogen metabolism

Allograft rejection

Histidine metabolism

Citrate cycle (TCA cycle)

Pentose phosphate pathway

Propanoate metabolism

Linoleic acid metabolism

Nitrogen metabolism

Ether lipid metabolism

Renin-angiotensin system

Oxidative phosphorylation

Graft-versus-host disease

Porphyrin and chlorophyll metabolism

Glycosaminoglycan degradation

Spliceosome

Phenylalanine metabolism

Aminoacyl-tRNA biosynthesis

Riboflavin metabolism

beta-Alanine metabolism

DNA replication

Ribosome

Selenoamino acid metabolism

Non-homologous end-joining

Other glycan degradation

Pantothenate and CoA biosynthesis

C21-Steroid hormone metabolism

Circadian rhythm - mammal

Glycine

serine and threonine metabolism

Asthma

leucine and isoleucine biosynthesis

Primary bile acid biosynthesis

Steroid biosynthesis

alpha-Linolenic acid metabolism

Folate biosynthesis

N-Glycan biosynthesis

Terpenoid backbone biosynthesis

Basal transcription factors

Pentose and glucuronate interconversions

Synthesis and degradation of ketone bodies

Ascorbate and aldarate metabolism

Glyoxylate and dicarboxylate metabolism

Limonene and pinene degradation

Nicotinate and nicotinamide metabolism

RNA degradation

One carbon pool by folate

Glycosphingolipid biosynthesis - globo series

Thiamine metabolism

Ubiquinone and other terpenoid-quinone biosynthesis

Caffeine metabolism

Biosynthesis of unsaturated fatty acids

Glycosphingolipid biosynthesis - ganglio series

Sulfur metabolism

Glycosphingolipid biosynthesis - lacto and neolacto series

Methane metabolism

Taurine and hypotaurine metabolism

Phenylalanine

tyrosine and tryptophan biosynthesis

Fatty acid biosynthesis

Fatty acid elongation in mitochondria

Protein export

Glycosylphosphatidylinositol(GPI)-anchor biosynthesis

Heparan sulfate biosynthesis

O-Glycan biosynthesis

RNA polymerase

Vitamin B6 metabolism

Biotin metabolism

D-Glutamine and D-glutamate metabolism

Chondroitin sulfate biosynthesis

D-Arginine and D-ornithine metabolism

Keratan sulfate biosynthesis

Lysine biosynthesis

Human 293

Human

E. coli

Plasma

HEK293

Leukocytes

Neutrophils

Pancreas

Pituitary

Neomycin

Puromycin

None

1

2

Yes

In Stock