活动过滤器
优化搜索结果
Target Symbol
- BRCA1 (428)
- BTK (322)
- GLUCOKINASE (296)
- BRCA2 (288)
- MENIN (276)
- TUBERIN (264)
- MLH1 (263)
- MSH2 (237)
- IFNG (230)
- RET (213)
- P53 (205)
- NOTCH3 (172)
- BDNF (167)
- FGFR1 (167)
- NF2 (159)
- PDE9A (155)
- VEGFA (150)
- ALPHA 1 ANTITRYPSIN (149)
- DISC1 (140)
- CONSTITUTIVE ANDROSTANE RECEPTOR (139)
- NRG1 (134)
- MORTALITY FACTOR 4 LIKE 2 (131)
- BIN1 (126)
- G PROTEIN ALPHA S (120)
- NDRG2 (120)
- WILMS TUMOR PROTEIN (119)
- IL10 (115)
- UBE2D3 (114)
- IRF5 (110)
- MU OPIOID RECEPTOR (107)
- RIBONUCLEASE INHIBITOR (107)
- EGFR (106)
- DYSTROBREVIN ALPHA (105)
- NCALD (105)
- LKB1 (104)
- PLAGL1 (103)
- BETA CATENIN (101)
- HMGA1 (101)
- MSH6 (100)
- TGIF (100)
- SSH3BP1 (99)
- MYOSIN (98)
- IL32 (97)
- TPM1 (97)
- ALKALINE PHOSPHATASE (96)
- CD46 (96)
- FHL1 (95)
- HNF 4 ALPHA (94)
- OSBPL9 (94)
- NAT1 (93)
- PML PROTEIN (93)
- MEIS2 (92)
- MTH1 (92)
- CAMK2B (88)
- MBNL1 (88)
- APC11 (87)
- AURORA A (87)
- P38 (87)
- HNRNP F (86)
- RUNX1T1 (86)
- CD59 (85)
- PQBP1 (85)
- PRKAR1B (85)
- CPNE1 (84)
- FH (84)
- PCBP2 (84)
- RAD17 (84)
- SYNTABULIN (84)
- TAU (84)
- ZFYVE27 (84)
- CAMKK2 (83)
- CHRM2 (83)
- MAX (83)
- NEK6 (83)
- CREM (82)
- GM CSF RECEPTOR ALPHA (82)
- PI 3 KINASE CATALYTIC SUBUNIT ALPHA (82)
- 14-3-3 ZETA (80)
- GIPC (79)
- MYADM (79)
- PPHLN1 (79)
- PPP2R2B (79)
- ASPARTATE BETA HYDROXYLASE (78)
- CAMK2D (78)
- CD44 (78)
- UBE2I (78)
- ABLIM2 (77)
- B RAF (77)
- GPR56 (77)
- MYELIN BASIC PROTEIN (77)
- TCF7L2 (77)
- TTC23 (77)
- PAK4 (76)
- APOL3 (75)
- FGF1 (75)
- P16INK4A (75)
- CACNB2 (74)
- DYSTROPHIN (74)
- JNK1 (74)
- OGG1 (74)
Reactivities
Applications
Expression Hosts
Lentivirus
Tags
- C-Myc/DDK (77343)
- Myc-DDK (70356)
- mGFP (36564)
- Tag Free (34775)
- TurboGFP (29559)
- C-MYC/DDK (19716)
- N-His (2056)
- N-GST and C-His (441)
- C-DDK (195)
- C-His (180)
- N-GST and C-HIS (150)
- C-6His (106)
- C-DDK/His (102)
- DDK-His (76)
- His-Tag (63)
- N-His-ABP (Albumin-Binding Protein) (52)
- C-HIS (45)
- C-Human Fc (44)
- His-tag (33)
- C-Mouse Fc and 6×His (30)
- C-Fc (28)
- C-8His (22)
- C-Mouse Fc (21)
- N-His-Trx (18)
- C-hFc (16)
- C-6×His (15)
- N-6His (15)
- C-Human Fc and 6×His (14)
- N-GST, C-His (13)
- C-Avi&6His (7)
- Tag-free (7)
- C- 6×His (6)
- N-GST (6)
- hIgG-Tag (6)
- C-10His (5)
- N-HIS (5)
- N-His PDCD1(Pro21-Val170) (5)
- N-Mouse Fc and C-6×His (5)
- N-Avi (4)
- N-His&C-His (4)
- N-His-GST (4)
- N-His/DDK (4)
- C-Fc/His (3)
- C-hFc&His (3)
- N-8His (3)
- hIgG-His-Tag (3)
- C-HUMAN (2)
- C-Myc-DDK (2)
- N-DDK (2)
- N-His-PDCD1(Pro21-Val170) (2)
- N-Human Fc (2)
- N-terminal His (2)
- N-terminal His-PDCD1(Pro21-Val170) tag (2)
- C-6xHis/AVI (1)
- C-AVI-PLUS (1)
- C-Avi-His (1)
- C-DDK-His (1)
- C-DDK/10xHis (1)
- C-DDK/6xHis (1)
- C-FC (1)
- C-HIS/C (1)
- C-HIS/DDK (1)
- C-His/DDK (1)
- C-Human Fc, Avi (1)
- C-Human Fc-Avi (1)
- C-hIgG1 Fc (1)
- C-hIgG4P Fc (1)
- C-mFc (1)
- C-terminal DDK (1)
- C-terminal His (1)
- N-6His-FLAG (1)
- N-8His&N-FLAG (1)
- N-AVI (1)
- N-Avi&6His (1)
- N-DDK/His (1)
- N-FLAG (1)
- N-FUSION (1)
- N-Fc-FLAG (1)
- N-Flag&C-His (1)
- N-GFP (1)
- N-GST(CKM) and N-His(CKB) (1)
- N-GST/C-His (1)
- N-Mouse Fc (1)
- N-T7 (1)
- N-TRX (1)
- N-TRXA (1)
- N-Trx-His (1)
- N-hFc (1)
- No (1)
- Tag free (1)
Vectors
- pCMV6-Entry (45038)
- pCMV6-AC-GFP (29601)
- pLenti-C-Myc-DDK-P2A-Puro (26347)
- pLenti-C-mGFP-P2A-Puro (26277)
- pRS (20309)
- pGFP-C-shLenti (20254)
- EF1a-GFP-P2A-Puro (19104)
- pCMV6-XL5 (10784)
- pLenti-C-Myc-DDK (10557)
- pLenti-C-mGFP (10288)
- pCMV6-XL4 (5164)
- pCMV6-AC (3791)
- pCMVMIR (1829)
- pGFP-V-RS (1369)
- RFP-BSD (1103)
- Luciferase-Puro (1102)
- mBFP-Neo (1102)
- GFP-puro (1101)
- pRFP-C-RS (932)
- pCMV6-XL6 (791)
- PCMV6-Neo (244)
- pCMV6-AC-Myc-DDK (132)
- pCMV6-XL5-DDK-His (76)
- pCMV6-AN-Myc-DDK (27)
- pRMT-tGFP, Promoter-less GFP Reporter Vector (3)
- pCMV6-Entry2 (1)
Reporters
Conjugates
Mutants
Assay Types
Brands
QC Levels
Families
- Druggable Genome (98085)
- Transmembrane (55981)
- WB (40474)
- Transcription Factors (24842)
- Secreted Protein (16469)
- Protein Kinase (9451)
- Protease (5952)
- ES Cell Differentiation/IPS (5864)
- Stem cell - Pluripotency (5162)
- GPCR (3591)
- Phosphatase (2585)
- Ion Channels: Other (1777)
- Adult stem cells (1391)
- Nuclear Hormone Receptor (1174)
- Embryonic stem cells (1111)
- Ion Channels: Potassium (875)
- Cancer stem cells (678)
- P450 (653)
- Induced pluripotent stem cells (621)
- Ion Channels: Cys-loop Receptors (509)
- Stem cell relevant signaling - JAK/STAT signaling pathway (437)
- Stem cell relevant signaling - TGFb/BMP signaling pathway (339)
- Ion Channels: Transient receptor potential (293)
- Stem cell relevant signaling - Wnt Signaling pathway (275)
- Stem cell relevant signaling - DSL/Notch pathway (258)
- Ion Channels: Glutamate Receptors (241)
- Ion Channels: Sodium (144)
- Ion Channels: ATP Receptors (111)
- Ion Channels: Calcium (88)
- Ion Channels: Cyclic nucleotide gated (68)
- ELISA (49)
- SDS-PAGE (33)
- Bioactivity (24)
- 10 mM Tris-HCl (12)
- the solution can be further dialyzed against PBS (phosphate buffered saline (12)
- Flow Cyt (11)
- 2 mM dithiothreitol (10)
-
ELISA.
Western Blot. (10) - e.g. Dulbecco's PBS). (10)
- Enzyme Activity (9)
- both dissolved in 9.5 M urea buffer (see above). Protofilaments and filament complexes are obtained by dialyzing the resulting polypeptide solution stepwise to a concentration of 4 M urea and then to low salt condition (50 mM NaCl (8)
-
Protein standard in 1D and 2D SDS gelelectrophoresis.
Immunoassays.
Immunization.
Protocol: Reconstitution to filaments is performed by mixing equimolar amounts of keratins of type I and type II at concentrations of approx. 0.5 mg/ml (6) - pH 7.4). For immunization purposes (6)
-
Protein standard in 1D and 2D SDS gelelectrophoresis.
Immunoassays.
Immunization.
Protocol: Reconstitution to filaments is performed by mixing equimolar amounts of keratins of type I and type II at concentrations of approx. 0.5 mg/ml (4) -
pH 7.4).
For immunization purposes (4) -
pH 7.4).
For immunization purposes (4) - Western Blot. (3)
- 0.1% (w/v) insulin (2)
- 10mM Tris-HCl (2)
- 1mM DTT (2)
- 2 mM dithiothreitol (2)
-
2mM EDTA.
2. Add 4ug of recombinant thioredoxin into reaction cocktail and mix immediately.
3. Incubate at 25°C for 20 minutes.
4. Record the increase in A650nm for 15 minutes (2) - 2mM dithiothreitol (2)
- 63mM sodium phosphate (2)
-
Protein standard in 1D and 2D SDS gelelectrophoresis.
Immunoassays.
Immunization.
Protocol: Reconstitution to filaments: After vimentin is dissolved in 9.5M Urea buffer (see above) (2) - Can be used as standard in a Sandwich ELISA. (2)
- FACS (2)
-
Protein standard in 1D and 2D SDS gelelectrophoresis.
Immunoassays.
Immunization.
Protocol: Reconstitution to filaments: after desmin is dissolved in 9.5 M urea buffer (see above) (2) -
Protocol: Activity Assay
1. Prepare a 1 ml reaction cocktail into a suitable container: The final concentrations are 5mM Tris (2) - Secreted (2)
-
both dissolved in 9.5 M urea buffer (see above).
Protofilaments and filament complexes are obtained by dialyzing the resulting polypeptide solution stepwise to a concentration of 4 M urea and then to low salt condition (50 mM NaCl (2) - e.g. Dulbeccos PBS). (2)
- e.g.Dulbecco's PBS). (2)
- protofilaments and filament complexes are obtained by dialyzing the resulting polypeptide solution stepwise to a concentration of 4M Urea and then to low salt condition (50mM NaCl (2)
- protofilaments and filament complexes are obtained by dialyzing the resulting polypeptide solution stepwise to a concentration of 4M urea and then to low salt condition (50 mM NaCl (2)
- the solution can be further dialyzed against PBS (Phosphate Buffered Saline (2)
-
ELISA.
Suitable for use as a Control or standard in indirect trapping ELISA for quantitation of antigen in serum using a standard curve.
Immunoprecipitation.
Western blotting. (1) -
ELISA.
Western Blot. (1) -
ELISA.
Western blotting. (1) - ELISA. (1)
- Positive control for Western blot analysis (1)
-
Positive control for Western blot analysis.
Standard for ELISA. (1) -
Adermann K. Role of the prosequence of guanylin. Protein Sci. 1999 Sep; 8(9): 1850-9.
4. Lauber T (1) -
Cell culture and/or animal studies.
ELISA.
Western Blot. (1) -
Cohen MB. Proguanylin secretion and the role of negative-feedback inhibition in a villous epithelial cell line. Am J Physiol Gastrointest Liver Physiol. 2002 Sep; 283(3): G695-702.
3. Schulz A (1) - For use as a Control or Standard in Indirect trapping ELISA for quantitation of antigen in serum using a standard curve (1)
-
For use as a Control or standard in indirect trapping ELISA for quantitation of antigen in serum using a standard curve.
Immunoprecipitation.
Western blotting. (1) - Forssmann WG (1)
- Hawkins JA (1)
- Hidaka Y (1)
- Marx UC (1)
-
Marx UC. Native and recombinant proguanylin feature identical biophysical properties and are monomeric in solution. Biochemistry. 2002 Dec 10; 41(49): 14602-12.
2. Rudolph JA (1) - Marx UC. Solution structure of human proguanylin: the role of a hormone prosequence. J Biol Chem. 2003 Jun 27; 278(26): 24118-24. Epub 2003 Apr 21. (1)
- Neudecker P (1)
- Nourse A (1)
- Rosch P (1)
- Schulz A (1)
- Shimonishi Y (1)
- Specific methodologies have not been tested using this product. (1)
-
Western Blot.
Protocol: 1. Lauber T (1) - Western Blotting. (1)
- for immunoprecipitation and for Wwestern blotting. (1)
Pathways
- Metabolic pathways (17830)
- Pathways in cancer (8698)
- MAPK signaling pathway (6039)
- Cytokine-cytokine receptor interaction (4714)
- Regulation of actin cytoskeleton (4287)
- Focal adhesion (4148)
- Neuroactive ligand-receptor interaction (3868)
- Endocytosis (3699)
- Chemokine signaling pathway (3524)
- Neurotrophin signaling pathway (3382)
- Insulin signaling pathway (3304)
- Wnt signaling pathway (3089)
- Ubiquitin mediated proteolysis (3079)
- Calcium signaling pathway (3073)
- Jak-STAT signaling pathway (2788)
- Huntington's disease (2766)
- Natural killer cell mediated cytotoxicity (2761)
- Purine metabolism (2738)
- Olfactory transduction (2737)
- Colorectal cancer (2690)
- Alzheimer's disease (2640)
- Cell cycle (2530)
- Prostate cancer (2504)
- Axon guidance (2496)
- T cell receptor signaling pathway (2485)
- Tight junction (2467)
- ErbB signaling pathway (2439)
- Pancreatic cancer (2424)
- Progesterone-mediated oocyte maturation (2410)
- Leukocyte transendothelial migration (2391)
- Cell adhesion molecules (CAMs) (2332)
- Oocyte meiosis (2249)
- Toll-like receptor signaling pathway (2228)
- GnRH signaling pathway (2167)
- Melanoma (2143)
- Apoptosis (2100)
- Melanogenesis (2086)
- B cell receptor signaling pathway (2041)
- Fc epsilon RI signaling pathway (2022)
- Chronic myeloid leukemia (1990)
- Lysosome (1987)
- Vascular smooth muscle contraction (1982)
- Fc gamma R-mediated phagocytosis (1956)
- Hematopoietic cell lineage (1948)
- Adherens junction (1941)
- Glioma (1924)
- Endometrial cancer (1913)
- Small cell lung cancer (1873)
- p53 signaling pathway (1856)
- VEGF signaling pathway (1850)
- Renal cell carcinoma (1828)
- Dilated cardiomyopathy (1820)
- Spliceosome (1783)
- Gap junction (1742)
- Systemic lupus erythematosus (1735)
- Parkinson's disease (1676)
- Hypertrophic cardiomyopathy (HCM) (1673)
- Non-small cell lung cancer (1637)
- Acute myeloid leukemia (1616)
- Pyrimidine metabolism (1582)
- TGF-beta signaling pathway (1548)
- Oxidative phosphorylation (1547)
- mTOR signaling pathway (1535)
- Long-term potentiation (1530)
- Adipocytokine signaling pathway (1509)
- Arrhythmogenic right ventricular cardiomyopathy (ARVC) (1491)
- Glycolysis / Gluconeogenesis (1489)
- Long-term depression (1486)
- Antigen processing and presentation (1477)
- Bladder cancer (1401)
- NOD-like receptor signaling pathway (1401)
- RIG-I-like receptor signaling pathway (1383)
- PPAR signaling pathway (1375)
- Epithelial cell signaling in Helicobacter pylori infection (1359)
- Complement and coagulation cascades (1332)
- Thyroid cancer (1327)
- Phosphatidylinositol signaling system (1323)
- Viral myocarditis (1293)
- Amyotrophic lateral sclerosis (ALS) (1259)
- Type II diabetes mellitus (1257)
- ECM-receptor interaction (1208)
- Pathogenic Escherichia coli infection (1190)
- Ribosome (1145)
- Cardiac muscle contraction (1143)
- Glycerophospholipid metabolism (1092)
- Drug metabolism - cytochrome P450 (1066)
- Metabolism of xenobiotics by cytochrome P450 (1055)
- Basal cell carcinoma (1044)
- Vibrio cholerae infection (1041)
- Cytosolic DNA-sensing pathway (1038)
- Amino sugar and nucleotide sugar metabolism (1028)
- Starch and sucrose metabolism (1026)
- Arginine and proline metabolism (988)
- Inositol phosphate metabolism (981)
- Primary immunodeficiency (971)
- Valine (906)
- Mismatch repair (888)
- Retinol metabolism (884)
- Hedgehog signaling pathway (877)
- Glutathione metabolism (848)
- Drug metabolism - other enzymes (846)
- Notch signaling pathway (835)
- RNA degradation (806)
- Arachidonic acid metabolism (803)
- Autoimmune thyroid disease (800)
- leucine and isoleucine degradation (773)
- Tyrosine metabolism (762)
- Pyruvate metabolism (752)
- Type I diabetes mellitus (750)
- Galactose metabolism (738)
- Maturity onset diabetes of the young (735)
- Fatty acid metabolism (734)
- Glycerolipid metabolism (730)
- Nucleotide excision repair (713)
- Proteasome (713)
- Homologous recombination (711)
- Lysine degradation (687)
- Sphingolipid metabolism (682)
- Tryptophan metabolism (671)
- Taste transduction (669)
- Cysteine and methionine metabolism (663)
- Graft-versus-host disease (662)
- Prion diseases (661)
- Dorso-ventral axis formation (650)
- Alanine (638)
- aspartate and glutamate metabolism (638)
- N-Glycan biosynthesis (637)
- Base excision repair (624)
- Fructose and mannose metabolism (620)
- Citrate cycle (TCA cycle) (616)
- Allograft rejection (607)
- Androgen and estrogen metabolism (605)
- Porphyrin and chlorophyll metabolism (587)
- SNARE interactions in vesicular transport (566)
- Butanoate metabolism (564)
- Propanoate metabolism (550)
- DNA replication (533)
- Ether lipid metabolism (532)
- Regulation of autophagy (523)
- Aminoacyl-tRNA biosynthesis (509)
- Pentose phosphate pathway (498)
- Glycine (485)
- serine and threonine metabolism (485)
- ABC transporters (479)
- Histidine metabolism (473)
- Nitrogen metabolism (468)
- Glycosphingolipid biosynthesis - lacto and neolacto series (454)
- Selenoamino acid metabolism (446)
- Linoleic acid metabolism (423)
- Basal transcription factors (415)
- Asthma (413)
- Nicotinate and nicotinamide metabolism (402)
- Glycosaminoglycan degradation (399)
- O-Glycan biosynthesis (398)
- beta-Alanine metabolism (382)
- RNA polymerase (379)
- Phenylalanine metabolism (369)
- Pentose and glucuronate interconversions (339)
- Glycosylphosphatidylinositol(GPI)-anchor biosynthesis (323)
- Ascorbate and aldarate metabolism (312)
- Sulfur metabolism (310)
- Pantothenate and CoA biosynthesis (307)
- Biosynthesis of unsaturated fatty acids (303)
- Riboflavin metabolism (302)
- Primary bile acid biosynthesis (295)
- Heparan sulfate biosynthesis (292)
- Renin-angiotensin system (291)
- Other glycan degradation (288)
- One carbon pool by folate (284)
- alpha-Linolenic acid metabolism (272)
- Glyoxylate and dicarboxylate metabolism (267)
- Keratan sulfate biosynthesis (261)
- Terpenoid backbone biosynthesis (260)
- Glycosphingolipid biosynthesis - globo series (252)
- Non-homologous end-joining (242)
- Chondroitin sulfate biosynthesis (240)
- Steroid biosynthesis (220)
- Circadian rhythm - mammal (216)
- C21-Steroid hormone metabolism (211)
- Limonene and pinene degradation (211)
- Glycosphingolipid biosynthesis - ganglio series (210)
- leucine and isoleucine biosynthesis (202)
- Folate biosynthesis (184)
- Taurine and hypotaurine metabolism (182)
- Caffeine metabolism (155)
- Thiamine metabolism (149)
- Synthesis and degradation of ketone bodies (142)
- Cyanoamino acid metabolism (137)
- Protein export (132)
- Fatty acid elongation in mitochondria (128)
- Ubiquinone and other terpenoid-quinone biosynthesis (107)
- Methane metabolism (102)
- Fatty acid biosynthesis (92)
- Phenylalanine (78)
- tyrosine and tryptophan biosynthesis (78)
- Vitamin B6 metabolism (69)
- Lipoic acid metabolism (61)
- Lysine biosynthesis (59)
- D-Glutamine and D-glutamate metabolism (56)
- O-Mannosyl glycan biosynthesis (36)
- Biotin metabolism (35)
- D-Arginine and D-ornithine metabolism (11)