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OriGene cDNAs in recent publications

Deficiency of Niemann-Pick Type C-1 Protein Impairs Release of Human Immunodeficiency Virus Type 1 and Results in Gag Accumulation in Late Endosomal/Lysosomal Compartments, J. Virol., Aug 2009; 83: 7982 - 7995. [NPC1]


Differential Effects on Cell Fusion Activity of Mutations in Herpes Simplex Virus 1 Glycoprotein B (gB) Dependent on Whether a gD Receptor or a gB Receptor Is Overexpressed, J. Virol., Aug 2009; 83: 7384 - 7390. [PILRA]


High Yield Heterologous Expression of Wild-type and Mutant Cu+-ATPase (ATP7B, Wilson Disease Protein) for Functional Characterization of Catalytic Activity and Serine Residues Undergoing Copper-dependent Phosphorylation, J. Biol. Chem., Aug 2009; 284: 21307 - 21316. [ATP7B]


Surfactant-Associated Protein B Is Critical to Survival in Nickel-Induced Injury in Mice, Am. J. Respir. Cell Mol. Biol., Aug 2009; 41: 226 - 236. [JUN]


The Importance of Heterogeneous Nuclear Ribonucleoprotein K on Cytochrome P450 2D2 Gene Regulation: Its Binding Is Reduced in Dark Agouti Rats, Drug Metab. Dispos., Aug 2009; 37: 1703 - 1710. [HNRNPK]


The Role of miR-206 in the Epidermal Growth Factor (EGF) Induced Repression of Estrogen Receptor- (ER) Signaling and a Luminal Phenotype in MCF-7 Breast Cancer Cells, Mol. Endocrinol., Aug 2009; 23: 1215 - 1230. [ESR1(ORF)]


View all citations on TrueClone

OriGene正式上线Zika病毒相关产品

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     Zika病毒是一种黄病毒属的单股正链RNA病毒,主要通过蚊虫进行传播,也有少量通过母婴传播。早在1947年Zika病毒已经被发现,直到2015年Zika疫情在巴西猛烈爆发,它才引起全球的高度关注。从巴西开始,寨卡疫情迅速在南美、中北美加勒比海地区蔓延开来,并进一步扩散到全球69个国家和地区。目前已经报道全球有近200万人感染了寨卡病毒。
     随着研究的深入,Zika病毒的危害逐渐被揭示,从最初的发烧、皮疹等轻微症状,到引起新生儿小头症和格林-巴利综合征等神经系统疾病。最近有研究均揭示,ZIKV在小鼠模型中引起睾丸损伤并最终导致雄性不育。研究者称目前寨卡病毒已经突破了血胎、血眼、血睾和血脑这人类的四大屏障,它对人类健康的影响不可低估。开发有效的疫苗及药物迫在眉睫(援引自科技日报,微信公众号kjrbwx,2016-12-15,寨卡病毒遭遇克星!中国科学家发现专门针对它的高效抗体)。
     OriGene致力于提供全面的基因组、蛋白组、抗体等研究工具和技术平台,使得科学家们可以研究整个生物学通路,从而对疾病的机制有更深的了解。现在OriGene很荣幸的宣布正式上线Zika病毒相关产品,助力您的科学研究。

Zika病毒研究资讯:

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