EXD2 (NM_018199) Human Untagged Clone
CAT＃: SC128176
EXD2 (untagged)-Human exonuclease 3'-5' domain containing 2 (EXD2), transcript variant 5
CNY 3656.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | C14orf114; EXDL2 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC128176 sequence for NM_018199 edited (data generated by NextGen Sequencing)
ATGGCCTCCCCAAGTGGCCTGTGTGTCTTGGTTCGCCTGCCCAAGCTAATCTGTGGAGGA AAAACACTACCAAGAACGTTATTGGATATTTTGGCAGATGGCACCATTTTGAAAGTTGGA GTGGGATGCTCAGAAGATGCCAGCAAGCTTCTGCAGGATTATGGCCTCGTTGTTAGGGGG TGCCTGGACCTCCGATACCTAGCCATGCGGCAGAGAAACAATTTGCTCTGTAATGGGCTT AGCCTGAAGTCCCTCGCTGAGACTGTTTTGAACTTTCCCCTTGACAAGTCCCTTCTACTT CGTTGCAGCAACTGGGATGCTGAGACTCTCACAGAGGACCAGGTAATTTATGCTGCCAGG GATGCCCAGATTTCAGTGGCTCTCTTTCTTCATCTTCTTGGATACCCTTTCTCTAGGAAT TCACCTGGAGAAAAAAACGATGACCACAGTAGCTGGAGAAAAGTCTTGGAAAAATGCCAG GGTGTGGTCGACATCCCATTTCGAAGCAAAGGAATGAGCAGATTGGGAGAAGAGGTTAAT GGGGAAGCAACAGAATCTCAGCAGAAGCCAAGAAATAAGAAGTCTAAGATGGATGGGATG GTGCCAGGCAACCACCAAGGGAGAGACCCCAGAAAACATAAAAGAAAGCCTCTGGGGGTG GGCTATTCTGCCAGAAAATCACCTCTTTATGATAACTGCTTTCTCCATGCTCCTGATGGA CAGCCCCTCTGCACTTGTGATAGAAGAAAAGCTCAGTGGTACCTGGACAAAGGCATTGGT GAGCTGGTGAGTGAAGAGCCCTTTGTGGTGAAGCTACGGTTTGAACCTGCAGGAAGGCCC GAATCTCCTGGAGACTATTACTTGATGGTTAAAGAGAACCTGTGTGTAGTGTGTGGCAAG AGAGACTCCTACATTCGGAAGAACGTGATTCCACATGAGTACCGGAAGCACTTCCCCATC GAGATGAAGGACCACAACTCCCACGATGTGCTGCTGCTCTGCACCTCCTGCCATGCCATT TCCAACTACTATGACAACCATCTGAAGCAGCAGCTGGCCAAGGAGTTCCAGGCCCCCATC GGCTCTGAGGAGGGCTTGCGCCTGCTGGAAGATCCTGAGCGCCGGCAGGTGCGTTCTGGG GCCAGGGCCCTGCTCAACGCGGAGAGCCTGCCTACTCAGCGAAAGGAGGAGCTGCTGCAA GCACTCAGAGAGTTTTATAACACAGACGTGGTCACAGAGGAGATGCTTCAAGAGGCTGCC AGCCTGGAGACCAGAATCTCCAATGAAAACTATGTTCCTCACGGGCTGAAGGTGGTGCAG TGTCACAGCCAGGGTGGCCTGCGCTCCCTCATGCAGCTGGAGAGCCGCTGGCGTCAGCAC TTCCTGGACTCCATGCAGCCCAAGCACCTGCCCCAGCAGTGGTCAGTGGACCACAACCAT CAGAAGCTGCTCCGGAAATTCGGGGAAGATCTTCCCATCCAGCTGTCTTGA Clone variation with respect to NM_018199.3 >OriGene 5' read for NM_018199 unedited
ACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGCCTCGTGCCGAATTCGGCACGA GGATCAAATCGAGCCCTTGCTTAGAAGTGAATTAGAAGATTTTCCAGTACTTGGAATTGA CTGTGAGTGGGTAAATTTGGAAGGCAAAGCCAGCCCTCTGTCACTTCTACAAATGGCCTC CCCAAGTGGCCTGTGTGTCTTGGTTCGCCTGCCCAAGCTAATCTGTGGAGGAAAAACACT ACCAAGAACGTTATTGGATATTTTGGCAGATGGCACCATTTTGAAAGTTGGAGTGGGATG CTCAGAAGATGCCAGCAAGCTTCTGCAGGATTATGGCCTCGTTGTTAGGGGGTGCCTGGA CCTCCGATACCTAGCCATGCGGCAGAGAAACAATTTGCTCTGTAATGGGCTTAGCCTGAA GTCCCTCGCTGAGACTGTTTTGAACTTTCCCCTTGACAAGTCCCTTCTACTTCGTTGCAG CAACTGGGATGCTGAGACTCTCACAGAGGACCAGGTAATTTATGCTGCCAGGGATGCCCA GATTTCAGTGGCTCTCTTTCTTCATCTTCTTGGATACCCTTTCTCTAGGAATTCACCTGG AGAAAAAAACGATGACCACAGTAGCTGGAGAAAAGTCTTGGAAAAATGCCANGGTGTGGT CGACATCCCATTTCGAAGCNAGGAATGAGCAGATTGGGAGAAAGAGGTTAATGGGGAAGA ACAGAATCTCAGCAGAAGCCAGAAATAAGAGTCTAGATGGATGGGATGGTGCCCAGGCAC CACCAGGGAGAGACCCAGAAACTAAAGAAGCTCTGGGGGGTGGGCTATCTGCAAAAATAC CTCTTAGATACTGCTTCTTCTGCTCTGAGGGAAGCCCTTGGACTGTGAAGAGAAACTTAN TGTACTGACAGGCATGTGANCTGGAGGAAACCCTTTGGAAACACCGTTACCCTCGGAGGC CATTT >OriGene 3' genomic read for NM_018199 unedited
CGGCCGCAATCTAGNATCGAGTTTTTTTTTTTTTTTTTTGAAATTTAAAATTTTATTTTT TTACCTTTTTTTTACATTTTTATTTTAAAATAAACAGTGTTTCCAAAAAACATTGACTAC AAGGGGGAAATGAGGCAATAAGGTTGGAAGAAGGGAAGGACTCAAGAAGAAATGCTGAAC CTGCAAACACAATGATCAGGGAGCATGCAGAGAGGCCCTTGCTGTGACACTGTCCTCTCA CTGCTACTCCTATGAAGCCCAGTGACTATGCTGGGACACTGGAGCTAAAGGGTCAAAGAG AAGCATTTCATTCCTAAAAGGTGATGTCAATTTGTACTTAGCCCCAGCAATGTGAATCCC CCTCTTCACAGTCCAATTCTAAGATTCCATTCTTAAGAAATTACCAAAGATAGAGCCAAA GAGATATATACAAGAAACTTTATCACATCATCATTGATAATAAAAGTATCTGAAACAACC AAAATTTTCAACAGTGTGGGGATGGATAAGGTAGAACCACTAGAAATCTATTTTCAAAGA TTTAAAAACATAGGAAGTTACTCGTGATACCATGTTAATCAGTGAGAGGGTAAAGTTAGG ATACCAACCTGTATCTATGTATGACCTTCAATTTTGTGTAAATATACACCTTATATGCAC TTTTTAATACTGAAAGGAAATTCATAAACATATCAGCAAAGTTTAGCTCTGTTTTAGATG GAGAGAAGATGGCTAATTTTTATTCTTTGNTTAGATTCTTCTGTAATGAGCATTGTTACT TTTATATCAGAAAAATAGACATTTGCCATANNATAAGTCTACCCTCAATCTCTGATTTAG ACGACATTTGTAGTCTTTAGAAAAGCTGCNTAAGTCAAGCAGACTCAAGAAAAAGATTCA ATCTAACAGTGACTCTCCCTGAAAAGATGAGAAATCTGTGTGACGCANCTGGCTTTTCCT CTACTTGCTGNGGCTTT |
| Restriction Sites | NotI-NotI |
| ACCN | NM_018199 |
| Insert Size | 4250 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_018199.1, NP_060669.1 |
| RefSeq Size | 2833 bp |
| RefSeq ORF | 1491 bp |
| Locus ID | 55218 |
| UniProt ID | Q9NVH0 |
| Domains | 3_5_exonuclease |
| Gene Summary | Exonuclease required for double-strand breaks resection and efficient homologous recombination. Plays a key role in controlling the initial steps of chromosomal break repair, it is recruited to chromatin in a damage-dependent manner and functionally interacts with the MRN complex to accelerate resection through its 3'-5' exonuclease activity, which efficiently processes double-stranded DNA substrates containing nicks.[UniProtKB/Swiss-Prot Function] Transcript Variant: This variant (5) is missing 2 internal exons compared to variant 1. This results in translation initiation from an in-frame downstream AUG and a shorter isoform (2) compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. |
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC200127 | EXD2 (Myc-DDK-tagged)-Human exonuclease 3'-5' domain containing 2 (EXD2), transcript variant 5 |
CNY 3656.00 |
|
| RC200127L1 | Lenti ORF clone of Human exonuclease 3'-5' domain containing 2 (EXD2), transcript variant 5, Myc-DDK-tagged |
CNY 6056.00 |
|
| RC200127L2 | Lenti ORF clone of Human exonuclease 3'-5' domain containing 2 (EXD2), transcript variant 5, mGFP tagged |
CNY 5890.00 |
|
| RC200127L3 | Lenti ORF clone of Human exonuclease 3'-5' domain containing 2 (EXD2), transcript variant 5, Myc-DDK-tagged |
CNY 5890.00 |
|
| RC200127L4 | Lenti ORF clone of Human exonuclease 3'-5' domain containing 2 (EXD2), transcript variant 5, mGFP tagged |
CNY 5890.00 |
|
| RG200127 | EXD2 (tGFP-tagged) - Human exonuclease 3'-5' domain containing 2 (EXD2), transcript variant 5 |
CNY 5256.00 |
