Mouse Nupr1l activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Nupr1l
Locus ID	69034
Kit Components	GA208025G1, Nupr1l gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA208025G2, Nupr1l gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA208025G3, Nupr1l gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_026916, NM_001359308
Synonyms	1810010E01Rik; 4930579G22Rik; Nupr2
Summary	Acts as a transcriptional repressor by inhibiting gene expression at the NUPR1 promoter in a p53/TP53-dependent manner in cancer cells. Involved in the G1 cell cycle arrest, and in a decrease in cell viability and cell proliferation of pancreatic cancer cells. Plays a role as a negative regulator of the protumoral factor NUPR1.[UniProtKB/Swiss-Prot Function]

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