Mouse Tgfbrap1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Tgfbrap1
Locus ID	73122
Kit Components	GA209406G1, Tgfbrap1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA209406G2, Tgfbrap1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA209406G3, Tgfbrap1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001013025, NM_001357299
Synonyms	3110018K12Rik; AU024090; AU042859; AW742551; Trap1
Summary	Plays a role in the TGF-beta/activin signaling pathway. It associates with inactive heteromeric TGF-beta and activin receptor complexes, mainly through the type II receptor, and is released upon activation of signaling. May recruit SMAD4 to the vicinity of the receptor complex and facilitate its interaction with receptor-regulated Smads, such as SMAD2 (By similarity).[UniProtKB/Swiss-Prot Function]

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