CD94 (KLRD1) Mouse Monoclonal Antibody [Clone ID: HP-3D9]

Specifications

Product Data
Clone Name	HP-3D9
Applications	FC
Recommend Dilution	Flow Cytometry analysis of human blood cells using 10 μl reagent / 100 μl of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Cultured human NK cells
Specificity	This antibody recognizes CD94, a 70 kDa type II transmembrane glycoprotein expressed on NK cells, NK-T cells, and subsets of CD8+ T cells and gamma/delta T cells.
Formulation	Phosphate buffered saline (PBS) Label: APC State: Liquid purified Ig fraction Stabilizer: 0.2% (w/v) high-grade protease free BSA Preservative: 15 mM sodium azide Label: Conjugated with cross-linked Allophycocyanin (APC) under optimum conditions. The conjugate is purified by size-exclusion chromatography and adjusted for direct use. No reconstitution is necessary.
Purification	The conjugate is purified by size-exclusion chromatography and adjusted for direct use. No reconstitution is necessary.
Conjugation	APC
Storage Condition	Store the antibody undiluted at 2-8°C. DO NOT FREEZE! This product is photosensitive and should be protected from light.
Gene Name	killer cell lectin like receptor D1
Database Link	Entrez Gene 3824 Human UniProt ID Q13241
Background	CD94, also known as KLRD1 (killer cell lectin-like receptor D1), is a transmembrane glycoprotein of the C-type lectin family, which forms disulfide-linked heterodimers with NKG2A, B, C, E, H proteins, constituting functionally distinct receptors of NK cells and related cell types. CD94/NKG2A and CD94/NKG2B heterodimers serve as inhibitory, whereas CD94/NKG2C and CD94/NKG2E as activating receptors. The ligand for CD94/NKG2 complexes has been identified as HLA-E. Extent of CD94 expression on NK cell surface can be used to demonstrate their progress through the differentiation process.
Synonyms	KLRD1, KP43, NK cell receptor
Reference Data

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