BCAR1 (NM_014567) Human 3' UTR Clone

Specifications

Product Data
Product Name	BCAR1 (NM_014567) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	CAS; CAS1; CASS1; CRKAS; P130Cas
ACCN	NM_014567
Insert Size	1360 bp
Sequence Data	Insert Sequence (showhide) >SC206721 3’UTR clone of NM_014567 The sequence shown below is from the reference sequence of NM_014567. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC CGCGTCCTAGGCCAGCTGGCAGCCGCCTGAGGGTGGTGACCCCAGGAGGGAGGCAGGGGAGGGGTGCGG CGGTCCCAGCTCCCTGGCTCCCATGTCAAGAGTCGCTGTGCCACAGGCTTAGGGACAGGACCCCAGCTC TGCGTCGGTCCTGGTGCCCTGGATGCCCAGGAATCTGTATATATTTATGGCCGGGCAGGGTGTGGGGCC ATGCCTCCTCAGGAGCCGAAGCCCAGGGGCCGGCCAGTGGCCTTCCCCAGCATGCACCACGGGCCCGGG TTGGGTCACCAGACGGGGCTGGAGTGTGAGGGTCCTGCAGCCTGCAGGACCTCGTGCCACCCCGAGGGC TGAGCCTGGTCCCACGAGGGTGCCGTGTCCCCTGACAGGGCCAGTGCAGTTTGGTGTGTCCTCCGCCTT ACCAGGAGAAGAACCTGAAGAACTATTTTTCGTTATTGGTTTTCCAATCATTTGACTAAGAGTCTCCAT TTAAATAAAGTTTTTAAAAGGAAGAGCAGCTGCCTGAGGGTGGCAGATGAGAGCAGCCCGGGGTGGGTG ACGGTTCTGGGGAAGGCACCCGGGGGCAAGGGCCATGCGTGGCATCTCCCGGGAGGGCAGAGGAGGAGT GGGTCTCTCTAGAAGAAAACCAAGGAACGCCGAGGCTGGGTGTCTCCTGGAGGCGGGGTGAGGCCTGCA GCTGGCCACAAGGCCCTGGGAGCCAGGGCAGAGCCTGGGCCCAAGAAAGGGGGCAGTTTCAGAGCTGCA GGGTCTGGGGCCCAGAAAGCACAGCCTGGGCATGGCCCCTGCAACCCTAGGGAGCTGCCACAGTGAGCA CCTGCCCATGCCCACAGCTGGCATCTGGAGTGAGGGCAGATTGGGGCAGGAACAGCTGCACAAGGGGAC GGGTTCCTGTGAGCCGAGGGCACCGCTGGGGGCTGCATCCAGAGCTCTGCTTAAAAGAATCTCATCCCA GCCTGCGGAACTCCCGAAGTGCACATGGAATTATACCTGGACCTGGCATCTGAGTTGGGAGGGAGGGGC TTGGAGAAGACCCTTGCCCTGGGCAAGTGTGTCCCCCTTCGTGGCTCCCCCACCCAGCAGCCCGCAGCC CAGATGGAAGCTTCAGGGTGCTTGGAACCCCTGGTGCTGCTCCCAGCCCTGACCGTTCTGCATATGAAC ATGGGCCTTGGTTTCCCCATCTGTATGAAGAAGGGAGTAGGGCTGGGTGATTCGCAAGCCCTCCTGATC TTACCTCTACAGAGGTTGTCCCCGTGACAGCATCTGTCCCCCCACCTCAGCCACATCATGCTCAGCCCA CCTGCCTTGGTGAGGACACAGAGGTAAAGGTGTATGCAGTTGCTCTCAA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_014567.5
Synonyms	CAS; CAS1; CASS1; CRKAS; P130Cas
Summary	The protein encoded by this gene is a member of the Crk-associated substrate (CAS) family of scaffold proteins, characterized by the presence of multiple protein-protein interaction domains and many serine and tyrosine phosphorylation sites. The encoded protein contains a Src-homology 3 (SH3) domain, a proline-rich domain, a substrate domain which contains 15 repeat of the YxxP consensus phosphorylation motif for Src family kinases, a serine-rich domain, and a bipartite Src-binding domain, which can bind both SH2 and SH3 domains. This adaptor protein functions in multiple cellular pathways, including in cell motility, apoptosis and cell cycle control. Dysregulation of this gene can have a wide range of effects, affecting different pathways, including cardiac development, vascular smooth muscle cells, liver and kidney function, endothelial migration, and cancer. [provided by RefSeq, Sep 2017]
Locus ID	9564
MW	47.7

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