RHOB (NM_004040) Human 3' UTR Clone

Specifications

Product Data
Product Name	RHOB (NM_004040) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	ARH6; ARHB; MST081; MSTP081; RHOH6
ACCN	NM_004040
Insert Size	1409 bp
Sequence Data	Insert Sequence (showhide) >SC214402 3' UTR clone of NM_004040 The sequence shown below is from the reference sequence of NM_004040. The complete sequence of this clone may contain minor differences, such as SNPs. Red=Cloning site Blue=Stop Codon CAATTGGCAGAGCTCAGAATTCAAGCGATCGC GCATCAACTGCTGCAAGGTGCTATGAGGGCCGCGCCCGTCGCGCCTGCCCCTGCCGGCACGGCTCCCCCT CCTGGACCAGTCCCCCGCGAGCCCGGAGAAGGGGAGACCCGTGTCCCACAAGGACCCCACCGGCCTGCCT GGCATCTGTCTGCTGACGCCTCTGGCTTGCGCCAGGACTTGGCGTGGGCACCGGGCGCCCCCATCCCAGT GTCTGTGTGCGTCCAGCTGTGTTGCACAGGCCTGGGCTCCCCACTGAGTGCCAAGGGTCCCCTGAGCATG CTTTTCTGAAGAGCCGGGCCTCAGAGTGTGTGGCTGTGTGTCTGTTCGACTCCCCTCGCCCCATTTTCAC CCCACCCCCGCCTCTGATCCCCGGGGGCGAGATTGGCGCGGGAGTGTGGCCGCGCCCCATCAGATGTTCT CCCTTCACCAGCGGGAGCTTGATATCCCTTGTCTGTAACATAGACCCCGGGTACTGCGGGAGGGGAGGGC TGCTGGGGAGGATGGGGGGATGTTATATAAATATAGATATAATTTTATTTTCGGAGCTAAGATGGTGTTA TTTAAGGGTGGTGATGGGTGAGCGCTCTGGCCCAGGCTGGGCCAGACTCCCGCCCAAGCATGAACAGGAC TTGACCATCTTTCCAACCCCTGGGGAAGACATTTGCAACTGACTTGGGGAGGACACAGCTTCAGCACAGC CTCTCCTGCGGGCCAGCCCGCTGCGAACCCTCCACCAGCTACCGGAGGGAGGAGGGAGGATGCGCTGTGG GGTTGTTTTTGCCATAAGCGAACTTTGTGCCTGTCCTAGAAGTGAAAATTGTTCAGTCCAAGAAACTGAT GTTATTTGATTTATTTAAAGGCTAAAATTTGTTTTTTTATTCTTTGCACAATTGTTTCATTGTTTGACAC TTAATGCACTCGTCATTTGCATACGACAGTAGCATTCTGACCACACTTGTACGCTGTAACCTCATCTACT TCTGATGTTTTTAAAAAATGACTTTTAACAAGGAGAGGGAAAAGAAACCCACTAAATTTTGCTTTGTTTC CTTGAAGAATGTGGCAACACTGTTTTGTGATTTTATTTGTGCAGGTCATGCACACAGTTTTGATAAAGGG CAGTAACAAGTATTGGGGCCTATTTTTTTTTTTTCCACAAGGCATTCTCTAAAGCTATGTGAAATTTTCT CTGCACCTCTGTACAGAGAATACACCTGCCCCTGTATATCCTTTTTTCCCCTCCCCTCCCTCCCAGTGGT ACTTCTACTAAATTGTTGTCTTGTTTTTTATTTTTTAAATAAACTGACAAATGACAAAATGGTGAGCTTA TGATGTTTACATAAAAGTTCTATAAGCTGTGTATACAGTTTTTTATGTAAAATATTAAAAGACTATGATG ATGACATTT ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_004040.2
Synonyms	ARH6; ARHB; MST081; MSTP081; RHOH6
Summary	Mediates apoptosis in neoplastically transformed cells after DNA damage. Not essential for development but affects cell adhesion and growth factor signaling in transformed cells. Plays a negative role in tumorigenesis as deletion causes tumor formation. Involved in intracellular protein trafficking of a number of proteins. Targets PKN1 to endosomes and is involved in trafficking of the EGF receptor from late endosomes to lysosomes. Also required for stability and nuclear trafficking of AKT1/AKT which promotes endothelial cell survival during vascular development. Serves as a microtubule-dependent signal that is required for the myosin contractile ring formation during cell cycle cytokinesis. Required for genotoxic stress-induced cell death in breast cancer cells.[UniProtKB/Swiss-Prot Function]
Locus ID	388

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