SIRT1 (NM_012238) Human 3' UTR Clone

Specifications

Product Data
Product Name	SIRT1 (NM_012238) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	SIR2; SIR2alpha; SIR2L1
ACCN	NM_012238
Insert Size	1827 bp
Sequence Data	Insert Sequence (showhide) >SC216574 3’UTR clone of NM_012238 The sequence shown below is from the reference sequence of NM_012238. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC GACATGAACTATCCATCAAACAAATCATAGTGTAATAATTGTGCAGGTACAGGAATTGTTCCACCAGCA TTAGGAACTTTAGCATGTCAAAATGAATGTTTACTTGTGAACTCGATAGAGCAAGGAAACCAGAAAGGT GTAATATTTATAGGTTGGTAAAATAGATTGTTTTTCATGGATAATTTTTAACTTCATTATTTCTGTACT TGTACAAACTCAACACTAACTTTTTTTTTTTTAAAAAAAAAAAGGTACTAAGTATCTTCAATCAGCTGT TGGTCAAGACTAACTTTCTTTTAAAGGTTCATTTGTATGATAAATTCATATGTGTATATATAATTTTTT TTGTTTTGTCTAGTGAGTTTCAACATTTTTAAAGTTTTCAAAAAGCCATCGGAATGTTAAATTAATGTA AAGGGAACAGCTAATCTAGACCAAAGAATGGTATTTTCACTTTTCTTTGTAACATTGAATGGTTTGAAG TACTCAAAATCTGTTACGCTAAACTTTTGATTCTTTAACACAATTATTTTTAAACACTGGCATTTTCCA AAACTGTGGCAGCTAACTTTTTAAAATCTCAAATGACATGCAGTGTGAGTAGAAGGAAGTCAACAATAT GTGGGGAGAGCACTCGGTTGTCTTTACTTTTAAAAGTAATACTTGGTGCTAAGAATTTCAGGATTATTG TATTTACGTTCAAATGAAGATGGCTTTTGTACTTCCTGTGGACATGTAGCAATGTCTATATTGGCTCAT AAAACTAACCTGAAAAACAAATAAATGCTTTGGAAATGTTTCAGTTGCTTTAGAAACATTAGTGCCTGC CTGGATCCCCTTAGTTTTGAAATATTTGCCATTGTTGTTTAAATACCTATCACTGTGGTAGAGCTTGCA TTGATCTTTTCCACAAGTATTAAACTGCCAAAATGTGAATATGCAAAGCCTTTCTGAATCTATAATAAT GGTACTTCTACTGGGGAGAGTGTAATATTTTGGACTGCTGTTTTCCATTAATGAGGAGAGCAACAGGCC CCTGATTATACAGTTCCAAAGTAATAAGATGTTAATTGTAATTCAGCCAGAAAGTACATGTCTCCCATT GGGAGGATTTGGTGTTAAATACCAAACTGCTAGCCCTAGTATTATGGAGATGAACATGATGATGTAACT TGTAATAGCAGAATAGTTAATGAATGAAACTAGTTCTTATAATTTATCTTTATTTAAAAGCTTAGCCTG CCTTAAAACTAGAGATCAACTTTCTCAGCTGCAAAAGCTTCTAGTCTTTCAAGAAGTTCATACTTTATG AAATTGCACAGTAAGCATTTATTTTTCAGACCATTTTTGAACATCACTCCTAAATTAATAAAGTATTCC TCTGTTGCTTTAGTATTTATTACAATAAAAAGGGTTTGAAATATAGCTGTTCTTTATGCATAAAACACC CAGCTAGGACCATTACTGCCAGAGAAAAAAATCGTATTGAATGGCCATTTCCCTACTTATAAGATGTCT CAATCTGAATTTATTTGGCTACACTAAAGAATGCAGTATATTTAGTTTTCCATTTGCATGATGTTTGTG TGCTATAGATGATATTTTAAATTGAAAAGTTTGTTTTAAATTATTTTTACAGTGAAGACTGTTTTCAGC TCTTTTTATATTGTACATAGTCTTTTATGTAATTTACTGGCATATGTTTTGTAGACTGTTTAATGACTG GATATCTTCCTTCAACTTTTGAAATACAAAACCAGTGTTTTTTACTTGTACACTGTTTTAAAGTCTATT AAAATTGTCATTTGACTTTTTTCTGTTAACTTA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_012238.5
Synonyms	SIR2; SIR2alpha; SIR2L1
Summary	This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2008]
Locus ID	23411
MW	70.6

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