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Oas3 (NM_145226) Mouse Untagged Clone
CAT＃: MC223723
Oas3 (untagged) - Mouse 2'-5' oligoadenylate synthetase 3 (Oas3), (10ug)
CNY 14,730.00
Product images
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
| Tag | Tag Free |
| Synonyms | Oasl10 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>MC223723 representing NM_145226
Red=Cloning site Blue=ORF Orange=Stop codon TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGGACCTGTTCCACACGCCAGCCGGAGCTCTGGATAAGCTGGTGGCCCACAACCTGCACCCAGCCCCTG AGTTCACAGCAGCCGTACGGGGTGCTCTGGGGTCGCTAAACATCACCCTACAGCAGCACAGAGCCCGAGG GTCACAGAGACCAAGAGTGATAAGGATTGCCAAGGGAGGAGCCTATGCCCGGGGCACAGCTCTCAGAGGT GGCACCGATGTCGAACTCGTCATCTTCCTCGACTGCTTCCAGAGCTTTGGTGACCAGAAGACCTGTCACT CAGAGACCCTGGGTGCCATGCGAATGTTGCTGGAGTCCTGGGGGGGCCACCCCGGGCCTGGCCTGACTTT TGAGTTTTCTCAGTCAAAGGCGTCCAGGATCTTACAGTTTCGTCTGGCATCGGCAGACGGAGAACACTGG ATAGATGTTAGCCTGGTGCCTGCCTTTGATGTCCTAGGACAGCCCCGCTCTGGAGTCAAGCCGACACCCA ACGTGTACTCCTCCCTCCTTAGCAGCCACTGCCAGGCCGGGGAGTACTCAGCCTGCTTCACTGAGCCCCG AAAGAACTTTGTGAACACTCGCCCAGCCAAGCTTAAGAACTTAATCCTGCTGGTCAAACACTGGTACCAC CAGGTGCAGACACGGGCCGTGAGGGCCACACTGCCCCCCAGCTACGCCCTAGAGCTGCTTACCATCTTTG CCTGGGAGCAGGGCTGTGGGAAGGACAGCTTCAGCCTGGCCCAAGGGCTCCGGACCGTCCTGGCCTTGAT CCAACACAGCAAGTACCTCTGCATTTTCTGGACGGAAAACTATGGCTTCGAGGACCCTGCAGTTGGAGAG TTCTTGCGAAGGCAGCTTAAGAGACCCAGGCCCGTGATCCTGGATCCAGCTGATCCAACGTGGGACGTGG GCAACGGGACAGCCTGGCGCTGGGATGTGCTGGCCCAGGAGGCTGAGTCCAGCTTTAGCCAGCAGTGCTT CAAGCAGGCCTCAGGAGTCCTTGTGCAGCCTTGGGAGGGGCCGGGCCTGCCACGGGCTGGGATCTTGGAT TTGGGCCACCCAATCTATCAAGGGCCTAACCAGGCCCTTGAAGACAACAAAGGCCACCTTGCTGTTCAGT CAAAGGAAAGGAGCCAAAAACCTTCCAATTCAGCTCCAGGATTTCCAGAAGCAGCCACCAAGATCCCTGC TATGCCCAACCCAAGTGCCAATAAAACCCGCAAGATCCGCAAGAAAGCAGCTCACCCAAAGACTGTCCAG GAAGCAGCATTGGATAGTATCTCAAGTCATGTTCGGATCACCCAGAGCACAGCATCCTCACACATGCCTC CTGACCGCTCTAGCATCTCCACCGCTGGGTCACGGATGAGCCCAGATCTGTCACAGATCCCCAGCAAGGA TCTAGACTGCTTCATCCAGGACCACCTTAGGCCGAGTCCCCAGTTCCAGCAGCAGGTGAAGCAGGCCATC GACGCCATCTTGTGCTGCCTCCGGGAGAAGAGTGTATACAAAGTCTTGAGGGTCAGCAAGGGCGGCTCTT TCGGCCGTGGCACAGACCTCAGGGGCAGCTGCGATGTGGAACTTGTCATCTTTTATAAAACCCTCGGGGA CTTCAAGGGCCAGAAGCCTCACCAGGCAGAGATCCTGCGTGACATGCAGGCCCAGCTACGACACTGGTGT CAGAACCCCGTGCCTGGACTGAGCCTCCAGTTTATTGAACAGAAGCCCAACGCTCTGCAACTCCAGCTGG CGTCCACCGACCTCAGCAACCGGGTGGACCTCAGTGTGCTGCCTGCTTTTGATGCTGTGGGGCCGCTGAA GTCCGGCACCAAACCTCAGCCCCAGGTGTACTCCTCGCTCCTCAGCAGCGGCTGCCAGGCTGGGGAGCAC GCAGCCTGCTTCGCAGAGCTTCGAAGGAACTTCATAAACACTTGCCCTCCCAAACTTAAGAGCCTGATGC TACTGGTCAAACACTGGTACCGCCAGGTTGTCACTCGATATAAAGGAGGAGAGGCGGCAGGTGATGCTCC GCCCCCAGCCTACGCCCTGGAGCTCCTGACCATCTTTGCCTGGGAACAAGGCTGTGGAGAGCAAAAGTTC AGCCTGGCTGAAGGCCTGCGGACCATCCTGAGGCTGATCCAACAGCACCAGTCGCTTTGTATCTACTGGA CGGTCAACTACAGTGTGCAGGACCCGGCCATCAGAGCACATCTTCTCTGCCAGCTTCGGAAAGCCAGGCC TCTAGTCCTGGACCCTGCAGATCCCACCTGGAACGTGGGCCAGGGCGACTGGAAGCTATTAGCTCAGGAG GCAGCTGCCCTTGGGTCACAAGTCTGCCTTCAGAGTGGGGATGGGACTCTGGTGCCACCCTGGGATGTGA CGCCAGCCCTCCTTCACCAGACCCTAGCTGAGGACCTGGACAAATTCATCAGTGAATTCCTCCAGCCCAA CCGCCACTTCCTGACTCAAGTGAAGAGAGCCGTGGACACCATATGTTCCTTCCTGAAAGAAAACTGCTTC CGGAACTCTACCATCAAGGTGCTCAAGGTGGTCAAGGGTGGGTCTTCTGCCAAAGGCACGGCTCTACAAG GACGCTCAGATGCCGACCTGGTGGTGTTTCTCAGCTGCTTCCGCCAGTTCTCTGAGCAAGGCAGCCATCG GGCAGAGATCATCTCGGAGATCCAGGCTCATCTGGAGGCGTGTCAGCAGATGCACAGCTTCGATGTCAAG TTTGAGGTCTCCAAGAGGAAGAACCCCCGAGTGCTCAGCTTCACGCTGACATCCCAGACGCTGCTGGACC AAAGCGTGGACTTTGACGTCCTGCCAGCCTTTGATGCTCTCGGCCAGCTGAGGTCCGGCTCTCGGCCTGA TCCCCGGGTCTACACAGACCTCATCCACAGCTGCAGTAATGCAGGAGAGTTCTCTACCTGCTTCACAGAG CTGCAGAGGGACTTCATTACCTCCCGTCCCACCAAACTCAAGAGCCTGATCCGGCTGGTGAAATACTGGT ACCAACAGTGTAACAAGACCATCAAGGGGAAGGGTTCCTTGCCTCCCCAGCACGGGCTGGAGCTCCTAAC TGTGTACGCCTGGGAGCAAGGTGGCCAGAATCCCCAGTTCAACATGGCGGAGGGCTTCCGCACTGTTCTG GAGCTGATTGTCCAGTACCGGCAGCTCTGCGTCTATTGGACCATCAACTACAGCGCAGAAGACAAGACCA TCGGTGACTTCCTGAAGATGCAGCTTCGGAAGCCCAGGCCTGTCATCCTGGACCCAGCTGACCCGACAGG CAACCTGGGCCACAACGCTCGCTGGGATCTGCTTGCCAAGGAGGCTACCGTGTACGCATCTGCCCTGTGC TGCGTGGACAGGGATGGCAATCCCATCAAGCCATGGCCGGTAAAGGCCGCTGTGTGA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_145226 |
| Insert Size | 3417 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_145226.2, NP_660261.1 |
| RefSeq Size | 4718 bp |
| RefSeq ORF | 3417 bp |
| Locus ID | 246727 |
| UniProt ID | Q8VI93 |
| Gene Summary | Interferon-induced, dsRNA-activated antiviral enzyme which plays a critical role in cellular innate antiviral response. In addition, it may also play a role in other cellular processes such as apoptosis, cell growth, differentiation and gene regulation. Synthesizes preferentially dimers of 2'-5'-oligoadenylates (2-5A) from ATP which then bind to the inactive monomeric form of ribonuclease L (RNase L) leading to its dimerization and subsequent activation. Activation of RNase L leads to degradation of cellular as well as viral RNA, resulting in the inhibition of protein synthesis, thus terminating viral replication. Can mediate the antiviral effect via the classical RNase L-dependent pathway or an alternative antiviral pathway independent of RNase L.[UniProtKB/Swiss-Prot Function] |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MG221387 | Oas3 (tGFP-tagged) - Mouse 2'-5' oligoadenylate synthetase 3 (Oas3), (10ug) |
CNY 11,020.00 |
|
| MR221387 | Oas3 (Myc-DDK-tagged) - Mouse 2'-5' oligoadenylate synthetase 3 (Oas3) |
CNY 7,928.00 |
|
| MR221387L3 | Lenti ORF clone of Oas3 (Myc-DDK-tagged) - Mouse 2'-5' oligoadenylate synthetase 3 (Oas3) |
CNY 11,880.00 |
|
| MR221387L4 | Lenti ORF clone of Oas3 (mGFP-tagged) - Mouse 2'-5' oligoadenylate synthetase 3 (Oas3) |
CNY 11,880.00 |
