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Oas3 (NM_145226) Mouse Tagged ORF Clone
CAT＃: MG221387
- TrueORF®
Oas3 (tGFP-tagged) - Mouse 2'-5' oligoadenylate synthetase 3 (Oas3), (10ug)
ORF Plasmid: DDK
"NM_145226" in other vectors (4)
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CNY 11,020.00
Product images
Specifications
| Product Data | |
| Type | Mouse Tagged ORF Clone |
| Tag | TurboGFP |
| Synonyms | Oasl10 |
| Vector | pCMV6-AC-GFP |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>MG221387 representing NM_145226
Red=Cloning site Blue=ORF Green=Tags(s) TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGGACCTGTTCCACACGCCAGCCGGAGCTCTGGATAAGCTGGTGGCCCACAACCTGCACCCAGCCCCTG AGTTCACAGCAGCCGTACGGGGTGCTCTGGGGTCGCTAAACATCACCCTACAGCAGCACAGAGCCCGAGG GTCACAGAGACCAAGAGTGATAAGGATTGCCAAGGGAGGAGCCTATGCCCGGGGCACAGCTCTCAGAGGT GGCACCGATGTCGAACTCGTCATCTTCCTCGACTGCTTCCAGAGCTTTGGTGACCAGAAGACCTGTCACT CAGAGACCCTGGGTGCCATGCGAATGTTGCTGGAGTCCTGGGGGGGCCACCCCGGGCCTGGCCTGACTTT TGAGTTTTCTCAGTCAAAGGCGTCCAGGATCTTACAGTTTCGTCTGGCATCGGCAGACGGAGAACACTGG ATAGATGTTAGCCTGGTGCCTGCCTTTGATGTCCTAGGACAGCCCCGCTCTGGAGTCAAGCCGACACCCA ACGTGTACTCCTCCCTCCTTAGCAGCCACTGCCAGGCCGGGGAGTACTCAGCCTGCTTCACTGAGCCCCG AAAGAACTTTGTGAACACTCGCCCAGCCAAGCTTAAGAACTTAATCCTGCTGGTCAAACACTGGTACCAC CAGGTGCAGACACGGGCCGTGAGGGCCACACTGCCCCCCAGCTACGCCCTAGAGCTGCTTACCATCTTTG CCTGGGAGCAGGGCTGTGGGAAGGACAGCTTCAGCCTGGCCCAAGGGCTCCGGACCGTCCTGGCCTTGAT CCAACACAGCAAGTACCTCTGCATTTTCTGGACGGAAAACTATGGCTTCGAGGACCCTGCAGTTGGAGAG TTCTTGCGAAGGCAGCTTAAGAGACCCAGGCCCGTGATCCTGGATCCAGCTGATCCAACGTGGGACGTGG GCAACGGGACAGCCTGGCGCTGGGATGTGCTGGCCCAGGAGGCTGAGTCCAGCTTTAGCCAGCAGTGCTT CAAGCAGGCCTCAGGAGTCCTTGTGCAGCCTTGGGAGGGGCCGGGCCTGCCACGGGCTGGGATCTTGGAT TTGGGCCACCCAATCTATCAAGGGCCTAACCAGGCCCTTGAAGACAACAAAGGCCACCTTGCTGTTCAGT CAAAGGAAAGGAGCCAAAAACCTTCCAATTCAGCTCCAGGATTTCCAGAAGCAGCCACCAAGATCCCTGC TATGCCCAACCCAAGTGCCAATAAAACCCGCAAGATCCGCAAGAAAGCAGCTCACCCAAAGACTGTCCAG GAAGCAGCATTGGATAGTATCTCAAGTCATGTTCGGATCACCCAGAGCACAGCATCCTCACACATGCCTC CTGACCGCTCTAGCATCTCCACCGCTGGGTCACGGATGAGCCCAGATCTGTCACAGATCCCCAGCAAGGA TCTAGACTGCTTCATCCAGGACCACCTTAGGCCGAGTCCCCAGTTCCAGCAGCAGGTGAAGCAGGCCATC GACGCCATCTTGTGCTGCCTCCGGGAGAAGAGTGTATACAAAGTCTTGAGGGTCAGCAAGGGCGGCTCTT TCGGCCGTGGCACAGACCTCAGGGGCAGCTGCGATGTGGAACTTGTCATCTTTTATAAAACCCTCGGGGA CTTCAAGGGCCAGAAGCCTCACCAGGCAGAGATCCTGCGTGACATGCAGGCCCAGCTACGACACTGGTGT CAGAACCCCGTGCCTGGACTGAGCCTCCAGTTTATTGAACAGAAGCCCAACGCTCTGCAACTCCAGCTGG CGTCCACCGACCTCAGCAACCGGGTGGACCTCAGTGTGCTGCCTGCTTTTGATGCTGTGGGGCCGCTGAA GTCCGGCACCAAACCTCAGCCCCAGGTGTACTCCTCGCTCCTCAGCAGCGGCTGCCAGGCTGGGGAGCAC GCAGCCTGCTTCGCAGAGCTTCGAAGGAACTTCATAAACACTTGCCCTCCCAAACTTAAGAGCCTGATGC TACTGGTCAAACACTGGTACCGCCAGGTTGTCACTCGATATAAAGGAGGAGAGGCGGCAGGTGATGCTCC GCCCCCAGCCTACGCCCTGGAGCTCCTGACCATCTTTGCCTGGGAACAAGGCTGTGGAGAGCAAAAGTTC AGCCTGGCTGAAGGCCTGCGGACCATCCTGAGGCTGATCCAACAGCACCAGTCGCTTTGTATCTACTGGA CGGTCAACTACAGTGTGCAGGACCCGGCCATCAGAGCACATCTTCTCTGCCAGCTTCGGAAAGCCAGGCC TCTAGTCCTGGACCCTGCAGATCCCACCTGGAACGTGGGCCAGGGCGACTGGAAGCTATTAGCTCAGGAG GCAGCTGCCCTTGGGTCACAAGTCTGCCTTCAGAGTGGGGATGGGACTCTGGTGCCACCCTGGGATGTGA CGCCAGCCCTCCTTCACCAGACCCTAGCTGAGGACCTGGACAAATTCATCAGTGAATTCCTCCAGCCCAA CCGCCACTTCCTGACTCAAGTGAAGAGAGCCGTGGACACCATATGTTCCTTCCTGAAAGAAAACTGCTTC CGGAACTCTACCATCAAGGTGCTCAAGGTGGTCAAGGGTGGGTCTTCTGCCAAAGGCACGGCTCTACAAG GACGCTCAGATGCCGACCTGGTGGTGTTTCTCAGCTGCTTCCGCCAGTTCTCTGAGCAAGGCAGCCATCG GGCAGAGATCATCTCGGAGATCCAGGCTCAGCTGGAGGCGTGTCAGCAGATGCACAGCTTCGATGTCAAG TTTGAGGTCTCCAAGAGGAAGAACCCCCGAGTGCTCAGCTTCACGCTGACATCCCAGACGCTGCTGGACC AAAGCGTGGACTTTGACGTCCTGCCAGCCTTTGATGCTCTCGGCCAGCTGAGGTCCGGCTCTCGGCCTGA TCCCCGGGTCTACACAGACCTCATCCACAGCTGCAGTAATGCAGGAGAGTTCTCTACCTGCTTCACAGAG CTGCAGAGGGACTTCATTACCTCCCGTCCCACCAAACTCAAGAGCCTGATCCGGCTGGTGAAATACTGGT ACCAACAGTGTAACAAGACCATCAAGGGGAAGGGTTCCTTGCCTCCCCAGCACGGGCTGGAGCTCCTAAC TGTGTACGCCTGGGAGCAAGGTGGCCAGAATCCCCAGTTCAACATGGCGGAGGGCTTCCGCACTGTTCTG GAGCTGATTGTCCAGTACCGGCAGCTCTGCGTCTATTGGACCATCAACTACAGCGCAGAAGACAAGACCA TCGGTGACTTCCTGAAGATGCAGCTTCGGAAGCCCAGGCCTGTCATCCTGGACCCAGCTGACCCGACAGG CAACCTGGGCCACAACGCTCGCTGGGATCTGCTTGCCAAGGAGGCTACCGTGTACGCATCTGCCCTGTGC TGCGTGGACAGGGATGGCAATCCCATCAAGCCATGGCCGGTAAAGGCCGCTGTG ACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAA >MG221387 representing NM_145226
Red=Cloning site Green=Tags(s) MDLFHTPAGALDKLVAHNLHPAPEFTAAVRGALGSLNITLQQHRARGSQRPRVIRIAKGGAYARGTALRG GTDVELVIFLDCFQSFGDQKTCHSETLGAMRMLLESWGGHPGPGLTFEFSQSKASRILQFRLASADGEHW IDVSLVPAFDVLGQPRSGVKPTPNVYSSLLSSHCQAGEYSACFTEPRKNFVNTRPAKLKNLILLVKHWYH QVQTRAVRATLPPSYALELLTIFAWEQGCGKDSFSLAQGLRTVLALIQHSKYLCIFWTENYGFEDPAVGE FLRRQLKRPRPVILDPADPTWDVGNGTAWRWDVLAQEAESSFSQQCFKQASGVLVQPWEGPGLPRAGILD LGHPIYQGPNQALEDNKGHLAVQSKERSQKPSNSAPGFPEAATKIPAMPNPSANKTRKIRKKAAHPKTVQ EAALDSISSHVRITQSTASSHMPPDRSSISTAGSRMSPDLSQIPSKDLDCFIQDHLRPSPQFQQQVKQAI DAILCCLREKSVYKVLRVSKGGSFGRGTDLRGSCDVELVIFYKTLGDFKGQKPHQAEILRDMQAQLRHWC QNPVPGLSLQFIEQKPNALQLQLASTDLSNRVDLSVLPAFDAVGPLKSGTKPQPQVYSSLLSSGCQAGEH AACFAELRRNFINTCPPKLKSLMLLVKHWYRQVVTRYKGGEAAGDAPPPAYALELLTIFAWEQGCGEQKF SLAEGLRTILRLIQQHQSLCIYWTVNYSVQDPAIRAHLLCQLRKARPLVLDPADPTWNVGQGDWKLLAQE AAALGSQVCLQSGDGTLVPPWDVTPALLHQTLAEDLDKFISEFLQPNRHFLTQVKRAVDTICSFLKENCF RNSTIKVLKVVKGGSSAKGTALQGRSDADLVVFLSCFRQFSEQGSHRAEIISEIQAQLEACQQMHSFDVK FEVSKRKNPRVLSFTLTSQTLLDQSVDFDVLPAFDALGQLRSGSRPDPRVYTDLIHSCSNAGEFSTCFTE LQRDFITSRPTKLKSLIRLVKYWYQQCNKTIKGKGSLPPQHGLELLTVYAWEQGGQNPQFNMAEGFRTVL ELIVQYRQLCVYWTINYSAEDKTIGDFLKMQLRKPRPVILDPADPTGNLGHNARWDLLAKEATVYASALC CVDRDGNPIKPWPVKAAV TRTRPLE - GFP Tag - V |
| Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
|
| ACCN | NM_145226 |
| ORF Size | 3414 bp |
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_145226.2, NP_660261.1 |
| RefSeq Size | 4718 bp |
| RefSeq ORF | 3417 bp |
| Locus ID | 246727 |
| UniProt ID | Q8VI93 |
| Gene Summary | Interferon-induced, dsRNA-activated antiviral enzyme which plays a critical role in cellular innate antiviral response. In addition, it may also play a role in other cellular processes such as apoptosis, cell growth, differentiation and gene regulation. Synthesizes preferentially dimers of 2'-5'-oligoadenylates (2-5A) from ATP which then bind to the inactive monomeric form of ribonuclease L (RNase L) leading to its dimerization and subsequent activation. Activation of RNase L leads to degradation of cellular as well as viral RNA, resulting in the inhibition of protein synthesis, thus terminating viral replication. Can mediate the antiviral effect via the classical RNase L-dependent pathway or an alternative antiviral pathway independent of RNase L.[UniProtKB/Swiss-Prot Function] |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MC223723 | Oas3 (untagged) - Mouse 2'-5' oligoadenylate synthetase 3 (Oas3), (10ug) |
CNY 14,730.00 |
|
| MR221387 | Oas3 (Myc-DDK-tagged) - Mouse 2'-5' oligoadenylate synthetase 3 (Oas3) |
CNY 7,928.00 |
|
| MR221387L3 | Lenti ORF clone of Oas3 (Myc-DDK-tagged) - Mouse 2'-5' oligoadenylate synthetase 3 (Oas3) |
CNY 11,880.00 |
|
| MR221387L4 | Lenti ORF clone of Oas3 (mGFP-tagged) - Mouse 2'-5' oligoadenylate synthetase 3 (Oas3) |
CNY 11,880.00 |
