United States
Germany
Japan
United Kingdom
China
RPTP mu (PTPRM) (NM_001105244) Human Tagged ORF Clone
CAT＃: RG226398
- TrueORF®
PTPRM (tGFP-tagged) - Human protein tyrosine phosphatase, receptor type, M (PTPRM), transcript variant 1
ORF Plasmid: DDK
"NM_001105244" in other vectors (4)
Need custom modification / cloning service?
Get a free quote
CNY 11,624.00
Product images
Specifications
| Product Data | |
| Type | Human Tagged ORF Clone |
| Tag | TurboGFP |
| Synonyms | hR-PTPu; PTPRL1; R-PTP-MU; RPTPM; RPTPU |
| Vector | pCMV6-AC-GFP |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>RG226398 representing NM_001105244
Red=Cloning site Blue=ORF Green=Tags(s) TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGAGGGGACTTGGGACTTGCCTGGCGACTTTGGCCGGACTTTTGCTAACTGCGGCGGGCGAGACGTTCT CAGGTGGCTGCCTCTTTGATGAGCCGTATAGCACATGTGGATATAGTCAATCTGAAGGTGATGACTTCAA TTGGGAGCAAGTGAACACCTTGACTAAACCGACTTCTGATCCATGGATGCCATCAGGTTCTTTCATGCTG GTGAATGCCTCTGGGAGACCTGAGGGGCAGAGAGCCCACCTGCTCTTACCCCAACTTAAAGAAAATGACA CCCACTGCATCGATTTTCACTATTTTGTGTCCAGCAAGAGTAATTCTCCTCCGGGGTTACTCAATGTCTA CGTGAAGGTCAATAACGGGCCACTGGGGAATCCTATCTGGAATATATCTGGAGACCCAACACGTACATGG AACAGGGCAGAACTGGCCATTAGTACTTTCTGGCCTAACTTTTATCAGGTGATTTTTGAAGTGATAACTT CTGGACATCAAGGCTATCTCGCTATCGATGAGGTGAAGGTGTTAGGACATCCATGTACCAGGACTCCTCA CTTCCTGCGGATTCAGAATGTGGAAGTTAATGCTGGCCAGTTTGCTACCTTCCAGTGCAGTGCCATCGGC AGGACCGTGGCAGGAGACAGGCTCTGGTTACAGGGCATTGATGTGCGAGATGCTCCTCTGAAGGAAATCA AGGTGACCAGCTCCCGACGCTTCATTGCTTCATTTAATGTTGTGAATACCACCAAACGAGATGCTGGAAA GTACCGCTGCATGATTCGCACTGAAGGAGGTGTTGGAATATCAAACTATGCAGAGTTGGTAGTTAAAGAA CCACCCGTTCCTATTGCCCCACCTCAGCTCGCCTCTGTAGGAGCCACCTACCTGTGGATACAGCTCAACG CCAACTCCATCAATGGGGATGGGCCCATTGTGGCCCGAGAGGTGGAGTACTGCACGGCCAGTGGGAGCTG GAATGACCGGCAGCCAGTCGATTCCACGAGCTATAAAATTGGACACCTTGACCCAGATACAGAATATGAG ATTAGTGTGCTCCTGACCAGGCCAGGGGAGGGTGGCACTGGCTCTCCTGGTCCAGCTCTCAGGACAAGAA CAAAGTGTGCTGATCCCATGCGAGGCCCAAGAAAACTAGAAGTAGTGGAGGTCAAATCTCGGCAAATCAC TATCCGCTGGGAGCCATTTGGATATAATGTAACTCGTTGCCACAGTTATAATCTCACTGTCCACTACTGT TACCAAGTTGGAGGACAAGAACAAGTGCGAGAAGAAGTAAGCTGGGATACAGAAAACTCACACCCTCAAC ACACGATCACTAACCTGTCACCATACACCAATGTCAGTGTGAAACTGATCCTCATGAACCCAGAGGGCCG GAAGGAAAGCCAAGAACTCATAGTGCAGACAGATGAAGACCTCCCAGGTGCTGTTCCCACTGAATCCATA CAAGGAAGTACCTTTGAAGAGAAGATATTTCTTCAGTGGAGAGAACCAACTCAAACATATGGTGTAATCA CTTTATATGAGATCACCTACAAAGCAGTCAGTTCCTTTGACCCAGAAATAGATTTATCCAATCAGAGTGG AAGAGTTTCAAAGCTGGGAAATGAAACCCATTTTCTGTTTTTTGGACTGTATCCGGGGACCACATACTCC TTTACCATCCGAGCTAGCACAGCTAAGGGTTTTGGGCCTCCAGCAACAAACCAGTTCACCACCAAAATAT CAGCACCCTCTATGCCAGCTTATGAACTTGAGACACCTTTGAATCAAACTGACAATACCGTGACAGTCAT GCTGAAACCTGCCCACAGCAGAGGAGCACCTGTCAGTGTCTATCAAATAGTTGTTGAGGAAGAACGTCCT CGAAGAACTAAAAAGACGACAGAAATCTTAAAGTGCTACCCAGTGCCAATTCACTTCCAGAATGCTTCTC TGCTGAACTCACAGTACTACTTTGCTGCAGAATTTCCTGCAGACAGCCTCCAAGCTGCGCAGCCTTTTAC AATTGGTGATAATAAGACATATAATGGATACTGGAACACTCCCCTTCTCCCCTATAAAAGCTACAGAATT TATTTCCAAGCTGCTAGTAGAGCCAATGGGGAAACCAAAATAGACTGTGTCCAAGTGGCCACAAAAGGAG CTGCCACTCCGAAACCAGTCCCAGAACCCGAGAAACAGACAGACCATACAGTTAAAATTGCTGGAGTCAT CGCGGGCATCTTGCTGTTCGTGATTATATTTCTTGGAGTTGTGTTGGTAATGAAGAAAAGGAAACTGGCC AAGAAGCGGAAAGAGACCATGAGCAGCACCCGACAGGAGATGACTGTGATGGTGAACTCAATGGACAAGA GCTATGCTGAGCAGGGCACAAACTGCGACGAGGCTTTCTCATTCATGGACACGCACAATCTGAATGGGAG ATCTGTGTCTTCACCATCGTCCTTCACAATGAAAACAAATACACTGAGCACATCGGTGCCTAATTCCTAT TACCCAGACCCATTTGTGCCAACTGCAATTTTAGTGCCAATAAATGATGAAACCCACACAATGGCCAGCG ATACCAGCAGCCTGGTGCAGTCCCATACTTACAAGAAGCGAGAGCCGGCCGACGTGCCCTATCAGACTGG GCAGCTCCACCCCGCCATCCGGGTGGCAGACCTCCTTCAGCACATCACACAGATGAAGTGTGCGGAGGGC TACGGCTTCAAGGAGGAATACGAGAGCTTCTTTGAAGGGCAGTCTGCACCATGGGACTCGGCTAAGAAAG ATGAGAACAGAATGAAGAACAGATACGGGAATATCATTGCATACGATCATTCCCGAGTGAGGCTGCAGAC AATAGAAGGAGACACAAACTCAGACTATATCAATGGCAATTATATCGATGGTTATCATCGACCCAATCAT TACATTGCTACCCAAGGGCCAATGCAGGAAACCATCTATGACTTCTGGAGGATGGTGTGGCACGAAAACA CTGCAAGTATCATCATGGTGACCAATCTTGTGGAAGTGGGAAGGGTCAAATGCTGCAAATACTGGCCAGA TGACACAGAGATATATAAAGACATTAAAGTTACCCTAATAGAAACAGAACTACTGGCAGAATATGTGATA AGAACATTTGCTGTTGAAAAGAGAGGTGTGCATGAAATCCGAGAGATCAGACAGTTTCACTTCACTGGCT GGCCGGATCATGGGGTCCCCTACCATGCCACCGGCCTGCTGGGATTCGTGCGGCAAGTCAAGTCCAAGAG CCCGCCCAGTGCAGGCCCACTGGTGGTGCACTGCAGTGCTGGTGCAGGGAGGACTGGCTGTTTCATCGTC ATTGATATCATGTTGGACATGGCCGAAAGGGAAGGGGTCGTAGACATCTACAACTGCGTCAGGGAGCTGC GGTCACGGAGGGTGAACATGGTGCAAACAGAGGAGCAGTATGTGTTTATCCACGATGCGATCCTGGAAGC CTGTCTTTGTGGGGACACCTCTGTGCCTGCTTCCCAAGTTAGGTCTCTGTATTATGACATGAACAAACTG GATCCACAGACAAACTCAAGCCAGATTAAAGAGGAATTCCGGACGCTAAACATGGTGACACCAACGCTGC GAGTAGAGGACTGCAGCATCGCACTGTTGCCCCGGAACCATGAGAAAAACCGGTGCATGGACATCCTGCC CCCAGACCGCTGCCTGCCCTTCCTCATCACCATCGATGGGGAGAGCAGCAACTACATCAATGCTGCCCTC ATGGACAGCTATAAACAGCCTTCAGCTTTTATAGTCACCCAGCATCCTTTGCCAAACACAGTGAAAGACT TTTGGAGACTGGTCCTGGATTATCACTGCACATCCGTAGTTATGCTAAATGATGTGGATCCTGCCCAGTT GTGTCCACAGTACTGGCCAGAAAACGGAGTACACAGACACGGCCCCATCCAGGTGGAATTTGTCTCTGCT GACCTGGAAGAGGACATCATCAGCAGGATATTCCGCATTTACAATGCCGCCAGACCCCAAGATGGATATC GGATGGTGCAGCAATTCCAGTTCCTGGGCTGGCCGATGTACAGGGACACACCAGTGTCTAAGCGCTCCTT CTTGAAGCTCATTCGCCAGGTGGACAAGTGGCAAGAGGAGTACAATGGCGGGGAAGGCCGCACGGTTGTG CACTGCTTGAACGGGGGAGGCCGCAGTGGGACGTTCTGCGCCATCAGCATCGTATGTGAGATGCTCCGGC ACCAGAGAACCGTGGATGTCTTTCACGCTGTGAAGACACTGAGGAACAACAAGCCCAACATGGTCGACCT CCTGGATCAGTACAAGTTCTGCTACGAGGTGGCCCTGGAATACTTGAATTCTGGC ACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAA >RG226398 representing NM_001105244
Red=Cloning site Green=Tags(s) MRGLGTCLATLAGLLLTAAGETFSGGCLFDEPYSTCGYSQSEGDDFNWEQVNTLTKPTSDPWMPSGSFML VNASGRPEGQRAHLLLPQLKENDTHCIDFHYFVSSKSNSPPGLLNVYVKVNNGPLGNPIWNISGDPTRTW NRAELAISTFWPNFYQVIFEVITSGHQGYLAIDEVKVLGHPCTRTPHFLRIQNVEVNAGQFATFQCSAIG RTVAGDRLWLQGIDVRDAPLKEIKVTSSRRFIASFNVVNTTKRDAGKYRCMIRTEGGVGISNYAELVVKE PPVPIAPPQLASVGATYLWIQLNANSINGDGPIVAREVEYCTASGSWNDRQPVDSTSYKIGHLDPDTEYE ISVLLTRPGEGGTGSPGPALRTRTKCADPMRGPRKLEVVEVKSRQITIRWEPFGYNVTRCHSYNLTVHYC YQVGGQEQVREEVSWDTENSHPQHTITNLSPYTNVSVKLILMNPEGRKESQELIVQTDEDLPGAVPTESI QGSTFEEKIFLQWREPTQTYGVITLYEITYKAVSSFDPEIDLSNQSGRVSKLGNETHFLFFGLYPGTTYS FTIRASTAKGFGPPATNQFTTKISAPSMPAYELETPLNQTDNTVTVMLKPAHSRGAPVSVYQIVVEEERP RRTKKTTEILKCYPVPIHFQNASLLNSQYYFAAEFPADSLQAAQPFTIGDNKTYNGYWNTPLLPYKSYRI YFQAASRANGETKIDCVQVATKGAATPKPVPEPEKQTDHTVKIAGVIAGILLFVIIFLGVVLVMKKRKLA KKRKETMSSTRQEMTVMVNSMDKSYAEQGTNCDEAFSFMDTHNLNGRSVSSPSSFTMKTNTLSTSVPNSY YPDPFVPTAILVPINDETHTMASDTSSLVQSHTYKKREPADVPYQTGQLHPAIRVADLLQHITQMKCAEG YGFKEEYESFFEGQSAPWDSAKKDENRMKNRYGNIIAYDHSRVRLQTIEGDTNSDYINGNYIDGYHRPNH YIATQGPMQETIYDFWRMVWHENTASIIMVTNLVEVGRVKCCKYWPDDTEIYKDIKVTLIETELLAEYVI RTFAVEKRGVHEIREIRQFHFTGWPDHGVPYHATGLLGFVRQVKSKSPPSAGPLVVHCSAGAGRTGCFIV IDIMLDMAEREGVVDIYNCVRELRSRRVNMVQTEEQYVFIHDAILEACLCGDTSVPASQVRSLYYDMNKL DPQTNSSQIKEEFRTLNMVTPTLRVEDCSIALLPRNHEKNRCMDILPPDRCLPFLITIDGESSNYINAAL MDSYKQPSAFIVTQHPLPNTVKDFWRLVLDYHCTSVVMLNDVDPAQLCPQYWPENGVHRHGPIQVEFVSA DLEEDIISRIFRIYNAARPQDGYRMVQQFQFLGWPMYRDTPVSKRSFLKLIRQVDKWQEEYNGGEGRTVV HCLNGGGRSGTFCAISIVCEMLRHQRTVDVFHAVKTLRNNKPNMVDLLDQYKFCYEVALEYLNSG TRTRPLE - GFP Tag - V |
| Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
|
| ACCN | NM_001105244 |
| ORF Size | 4395 bp |
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_001105244.2 |
| RefSeq Size | 5624 bp |
| RefSeq ORF | 4398 bp |
| Locus ID | 5797 |
| UniProt ID | P28827 |
| Protein Families | Druggable Genome, Phosphatase, Transmembrane |
| Protein Pathways | Adherens junction, Cell adhesion molecules (CAMs) |
| Gene Summary | The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem catalytic domains, and thus represents a receptor-type PTP. The extracellular region contains a meprin-A5 antigen-PTP mu (MAM) domain, an Ig-like domain and four fibronectin type III-like repeats. This PTP has been shown to mediate cell-cell aggregation through the interaction with another molecule of this PTP on an adjacent cell. This PTP can interact with scaffolding protein RACK1/GNB2L1, which may be necessary for the downstream signaling in response to cell-cell adhesion. Alternative splicing results in multiple transcripts encoding distinct isoforms. [provided by RefSeq, Jul 2008] |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC226398 | PTPRM (Myc-DDK-tagged)-Human protein tyrosine phosphatase, receptor type, M (PTPRM), transcript variant 1 |
CNY 10,024.00 |
|
| RC226398L3 | Lenti-ORF clone of PTPRM (Myc-DDK-tagged)-Human protein tyrosine phosphatase, receptor type, M (PTPRM), transcript variant 1 |
CNY 16,530.00 |
|
| RC226398L4 | Lenti-ORF clone of PTPRM (mGFP-tagged)-Human protein tyrosine phosphatase, receptor type, M (PTPRM), transcript variant 1 |
CNY 16,530.00 |
|
| SC317168 | PTPRM (untagged)-Human protein tyrosine phosphatase, receptor type, M (PTPRM), transcript variant 1 |
CNY 10,032.00 |
其它RPTP mu产品
