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IGLL1 (NM_152855) Human Untagged Clone
CAT＃: SC108252
IGLL1 (untagged)-Human immunoglobulin lambda-like polypeptide 1 (IGLL1), transcript variant 2
CNY 1,800.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | 14.1; AGM2; CD179b; IGL1; IGL5; IGLJ14.1; IGLL; IGO; IGVPB; VPREB2 |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene sequence for NM_152855 edited
GAATTCGGCACCAGTGCCAGCGAGAGGGACCAGGGCACCACTCTCTAGGGAGCCCACACT GCAAGTCAGGCCACAAGGACCTCTGACCCTGAGGGCCGATGAGGCCAGGGACAGGCCAGG GGGGCCTTGAGGCCCCTGGTGAGCCAGGCCCCAACCTCAGGCAGCGCTGGCCCCTGCTGC TGCTGGGTCTGGCCGTGGTAACCCATGGCCTGCTGCGCCCAACAGCTGCATCGCAGAGCA GGGCCCTGGGCCCTGGAGCCCCTGGAGGAAGCAGCCGGTCCAGCCTGAGGAGCCGGTGGG GCAGGTTCCTGCTCCAGCGCGGCTCCTGGACTGGCCCCAGGTGCTGGCCCCGGGGGTTTC AATCCAAGCATAACTCAGTGACGCATGTGTTTGGCAGCGGGACCCAGCTCACCGTTTTAA GTCAGCCCAAGGCCACCCCCTCGGTCACTCTGTTCCCGCCGTCCTCTGAGGAGCTCCAAG CCAACAAGGCTACACTGGTGTGTCTCATGAATGACTTTTATCCGGGAATCTTGACGGTGA CCTGGAAGGCAGATGGTACCCCCATCACCCAGGGCGTGGAGATGACCACGCCCTCCAAAC AGAGCAACAACAAGTACGCGGCCAGCAGCTACCTGAGCCTGACGCCCGAGCAGTGGAGGT CCCGCAGAAGCTACAGCTGCCAGGTCATGCACGAAGGGAGCACCGTGGAGAAGACGGTGG CCCCTGCAGAATGTTCATAGGTTCCCAGCCCCGACCCCACCCAAAGGGGCCTGGAGCTGC AGGATCCCAGGGGAAGGGTCTCTCTCTGCATCCCAAGCCATCCAGCCCTTCTCCCTGTAC CCAGTAAACCCTAAATAAATACCCTCTTTGTCAACCAGAAAAAAAAAAAAAAAAAAAAAA AACTCGAC >OriGene 5' read for NM_152855 unedited
NTAAAGTTCAGGATTTTGTAATACGACTCACTATAGGGGCGGCGCGCGAATTCGCACCAG TGCCAGCGAGAGGGACCAGGGCACCACTCTGTGGGGAGCCCACACTGCAAGTCAGGCCAC AAGGACCTCTGACCCTGAGGGCCGATGAGGCCAGGGACAGGCCAGGGGGGCCTTGAGGCC CCTGGTGAGCCAGGCCCCAACCTCAGGCAGCGCTGGCCCCTGCTGCTGCTGGGTCTGGCC GTGGTAACCCAGGGGCTGCTGCGCCCAACAGCTGCATCGCAGAGCAGGGCCCTGGGCCCT GGAGCCCCTGGAGGAAGCAGCCGGTCCAGCCTGAGGAGCCGGTGGGGCAGGTTCCTGCTC CAGCGCGGCTCCTGGACTGGCCCCAGGTGCTGGCCCCGGGGGTTTCAATCCAAGCATAAC TCAGTGACGCATGTGTTTGGCAGCGGGACCCAGCTCACCGTTTTAAGTCAGCCCAAGGCC ACCCCCTCGGTCACTCTGTTCCCGCCGTCCTCTGAGGAGCTCCAAGCCAACAAGGCTACA CTGGTGTGTCTCATGAATGACTTTTATCCGGGAATCTTGACGGTGACCTGGAAGGCAGAT GGTACCCCCATCACCCAGGGCGTGGAGATGACCACGCCCTCCAAACAGAGCAACAACAAG TACGCGGCCAGCAGCTACCTGAGCCTGACGCCCGAGCAGTGGAGGTCCCGCAGAAGCTAC AGCTGCCAGGTCATGCACGAAGGGAGCACCGTGGAGAAGACGGTGGCCCCTGCAGAAGTT CATAGGTTCCCAGCCCCGACCCACCCAAAGGGGCCTGGAGCTGCAGGATCCCAGGGGAGG GTGTCTCTCTGCATCCCAAGCCATCCAGCCCTTCTCCTGTACCCAGTAAACCTAAAAAAT ACCCTCTTA >OriGene 3' read for NM_152855 unedited
CNATTTTATATCTTTTTTTTTTTTTTTTCGGTTGACAAAAAGGTATTTATTTAGGGTTTA CTGGGTACAGGGAGAAGGGCTGGATGGCTTGGGATGCAGAGAGAGACCCTTCCCCTGGGA TCCTGCAGCTCCAGGCCCCTTTGGGTGGGGTCGGGGCTGGGAACCTATGAACATTCTGCA GGGGCCACCGTCTTCTCCACGGTGCTCCCTTCGTGCATGACCTGGCAGCTGTAGCTTCTG CGGGACCTCCACTGCTCGGGCGTCAGGCTCAGGTAGCTGCTGGCCGCGTACTTGTTGTTG CTCTGTTTGGAGAGGCGTGGTCATCTCCACGCCCTGGGTGATGGGGGTACCATCTGCCTT CCAGGTCACCGTCAAGATTCCCGGATAAAAGTCATTCATGAGACACACCAGTGTAGCCTT GTTGGCTTGGAGCTCCTCAGAGGACGGCGGGAACAGAGTGACCGAGGGGGTGGCCTTGGG CTGACTTAAAACGGTGAGCTGGGTCCCGCTGCCAAACACATGCGTCACTGAGTTATGCTT GGATTGAAACCCCCGGGGCCAGCACCTGGGGCCAGTCCAGGAGCCGCGCTGGAGCAGGAA CCTGCCCCACCGGCTCCTCAGGCTGGACCCGCTGCTTCCTGCAGGGGCTCCAGGGCCCAG GGCCCTGCTCTGCGATGCAACTGTTGGGCGCAACATGCCTGGGGTTACCACGGGCAGACC CAGCAGCACCGGGGGCCAACGCTGCCTGAGGTTGGGGCCTGGTTCACCAGGGCCCTAAGG GCCCCCTGGCCTGTCCCTGGCCTCATAGA |
| Restriction Sites | NotI-NotI |
| ACCN | NM_152855 |
| Insert Size | 1000 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_152855.1, NP_690594.1 |
| RefSeq Size | 785 bp |
| RefSeq ORF | 255 bp |
| Locus ID | 3543 |
| UniProt ID | P15814 |
| Protein Families | Secreted Protein |
| Protein Pathways | Primary immunodeficiency |
| Gene Summary | The preB cell receptor is found on the surface of proB and preB cells, where it is involved in transduction of signals for cellular proliferation, differentiation from the proB cell to the preB cell stage, allelic exclusion at the Ig heavy chain gene locus, and promotion of Ig light chain gene rearrangements. The preB cell receptor is composed of a membrane-bound Ig mu heavy chain in association with a heterodimeric surrogate light chain. This gene encodes one of the surrogate light chain subunits and is a member of the immunoglobulin gene superfamily. This gene does not undergo rearrangement. Mutations in this gene can result in B cell deficiency and agammaglobulinemia, an autosomal recessive disease in which few or no gamma globulins or antibodies are made. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] Transcript Variant: This variant (2) lacks an alternate exon compared to variant 1, which causes a frameshift. The resulting isoform (b) is shorter and has a distinct C-terminus compared to isoform a. |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC212951 | IGLL1 (Myc-DDK-tagged)-Human immunoglobulin lambda-like polypeptide 1 (IGLL1), transcript variant 2 |
CNY 1,920.00 |
|
| RC212951L3 | Lenti-ORF clone of IGLL1 (Myc-DDK-tagged)-Human immunoglobulin lambda-like polypeptide 1 (IGLL1), transcript variant 2 |
CNY 5,890.00 |
|
| RC212951L4 | Lenti-ORF clone of IGLL1 (mGFP-tagged)-Human immunoglobulin lambda-like polypeptide 1 (IGLL1), transcript variant 2 |
CNY 5,890.00 |
|
| RG212951 | IGLL1 (tGFP-tagged) - Human immunoglobulin lambda-like polypeptide 1 (IGLL1), transcript variant 2 |
CNY 3,520.00 |
