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IRF3 (NM_001571) Human Untagged Clone
CAT＃: SC119140
IRF3 (untagged)-Human interferon regulatory factor 3 (IRF3), transcript variant 1
CNY 2,950.00
| Cited in 1 publication. |
Product images
CNY 1,999.00
CNY 2,700.00
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | IIAE7 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene sequence for NM_001571 edited
CCCACGCGTCCGCTACCCTGAAAGTGGGGATACTTACTTTCGATGATGTGGGGGAGGGAG GAGGTCTATACTGGCGGAATTGAGGGAGTGGAGGGTCTGCACTGAAGACGCTGGGGAAGG ATGTGCCATGGATATGGGAAGGAACCCTAGCTGATTAGAGAGCCTCTCGGGAGGATGGGA GGATGGGAAGAGGAGGTTTCCTGTTTGTACCCCCGAAAATATGGGTGAAGGACCTGTGCC GTGGCCCGTGAGAAGGAGGTCTGGGTGCGGAAACTCCAGGCCAGGTGGGTCCGGGGGAGG CCGGTCGCGCCCAGGAAATGCCCTATACGCGCAGGCCGGACCATGGGAACCCCAAAGCCA CGGATCCTGCCCTGGCTGGTGTCGCAGCTGGACCTGGGGCAACTGGAGGGCGTGGCCTGG GTGAACAAGAGCCGCACGCGCTTCCGCATCCCTTGGAAGCACGGCCTACGGCAGGATGCA CAGCAGGAGGATTTCGGAATCTTCCAGGCCTGGGCCGAGGCCACTGGTGCATATGTTCCC GGGAGGGATAAGCCAGACCTGCCAACCTGGAAGAGGAATTTCCGCTCTGCCCTCAACCGC AAAGAAGGGTTGCGTTTAGCAGAGGACCGGAGCAAGGACCCTCACGACCCACATAAAATC TACGAGTTTGTGAACTCAGGAGTTGGGGACTTTTCCCAGCCAGACACCTCTCCGGACACC AATGGTGGAGGCAGTACTTCTGATACCCAGGAAGACATTCTGGATGAGTTACTGGGTAAC ATGGTGTTGGCCCCACTCCCAGATCCGGGACCCCCAAGCCTGGCTGTAGCCCCTGAGCCC TGCCCTCAGCCCCTGCGGAGCCCCAGCTTGGACAATCCCACTCCCTTCCCAAACCTGGGG CCCTCTGAGAACCCACTGAAGCGGCTGTTGGTGCCGGGGGAAGAGTGGGAGTTCGAGGTG ACAGCCTTCTACCGGGGCCGCCAAGTCTTCCAGCAGACCATCTCCTGCCCGGAGGGCCTG CGGCTGGTGGGGTCCGAAGTGGGAGACAGGACGCTGCCTGGATGGCCAGTCACACTGCCA GACCCTGGCATGTCCCTGACAGACAGGGGAGTGATGAGCTACGTGAGGCATGTGCTGAGC TGCCTGGGTGGGGGACTGGCTCTCTGGCGGGCCGGGCAGTGGCTCTGGGCCCAGCGGCTG GGGCACTGCCACACATACTGGGCAGTGAGCGAGGAGCTGCTCCCCAACAGCGGGCATGGG CCTGATGGCGAGGTCCCCAAGGACAAGGAAGGAGGCGTGTTTGACCTGGGGCCCTTCATT GTAGATCTGATTACCTTCACGGAAGGAAGCGGACGCTCACCACGCTATGCCCTCTGGTTC TGTGTGGGGGAGTCATGGCCCCAGGACCAGCCGTGGACCAAGAGGCTCGTGATGGTCAAG GTTGTGCCCACGTGCCTCAGGGCCTTGGTAGAAATGGCCCGGGTAGGGGGTGCCTCCTCC CTGGAGAATACTGTGGACCTGCACATTTCCAACAGCCACCCACTCTCCCTCACCTCCGAC CAGTACAAGGCCTACCTGCAGGACTTGGTGGAGGGCATGGATTTCCAGGGCCCTGGGGAG AGCTGAGCCCTCGCTCCTCATGGTGTGCCTCCAACCCCCCTGTTCCCCACCACCTCAACC AATAAACTGGTTCCTGCTATGAAAAAAAAAAAAAAA |
| Restriction Sites | NotI-NotI |
| ACCN | NM_001571 |
| Insert Size | 1700 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_001571.2, NP_001562.1 |
| RefSeq Size | 1648 bp |
| RefSeq ORF | 1284 bp |
| Locus ID | 3661 |
| UniProt ID | Q14653 |
| Domains | IRF |
| Protein Families | Druggable Genome, Transcription Factors |
| Protein Pathways | Cytosolic DNA-sensing pathway, RIG-I-like receptor signaling pathway, Toll-like receptor signaling pathway |
| Gene Summary | This gene encodes a member of the interferon regulatory transcription factor (IRF) family. The encoded protein is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon-induced genes. The protein plays an important role in the innate immune response against DNA and RNA viruses. Mutations in this gene are associated with Encephalopathy, acute, infection-induced, herpes-specific, 7. [provided by RefSeq, Sep 2020] Transcript Variant: This variant (1) encodes isoform 1. |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
FoxO1 Negatively Regulates Cellular Antiviral Response by Promoting Degradation of IRF3
,Cao-Qi Lei, Yu Zhang, Tian Xia, Li-Qun Jiang, Bo Zhong, and Hong-Bing Shu,
J. Biol. Chem., May 2013; 288: 12596 - 12604.
,PubMed ID 23532851
[IRF3]
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC209951 | IRF3 (Myc-DDK-tagged)-Human interferon regulatory factor 3 (IRF3), transcript variant 1 |
CNY 3,656.00 |
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| RC209951L1 | Lenti ORF clone of Human interferon regulatory factor 3 (IRF3), transcript variant 1, Myc-DDK-tagged |
CNY 5,890.00 |
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| RC209951L2 | Lenti ORF clone of Human interferon regulatory factor 3 (IRF3), transcript variant 1, mGFP tagged |
CNY 5,890.00 |
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| RC209951L3 | Lenti ORF clone of Human interferon regulatory factor 3 (IRF3), transcript variant 1, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC209951L4 | Lenti ORF clone of Human interferon regulatory factor 3 (IRF3), transcript variant 1, mGFP tagged |
CNY 5,890.00 |
|
| RG209951 | IRF3 (tGFP-tagged) - Human interferon regulatory factor 3 (IRF3), transcript variant 1 |
CNY 4,370.00 |
