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Factor H (CFH) (NM_000186) Human Untagged Clone
CAT＃: SC120040
CFH (untagged)-Human complement factor H (CFH), transcript variant 1
CNY 12,864.00
Product images
CNY 1,999.00
CNY 2,700.00
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | AHUS1; AMBP1; ARMD4; ARMS1; CFHL3; FH; FHL1; HF; HF1; HF2; HUS |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene sequence for NM_000186 edited
GAATTCGGCACGAGGGGACGTTGTGAACAGAGTTAGCTGGTAAATGTCCTCTTAAAAGAT CCAAAAAATGAGACTTCTAGCAAAGATTATTTGCCTTATGTTATGGGCTATTTGTGTAGC AGAAGATTGCAATGAACTTCCTCCAAGAAGAAATACAGAAATTCTGACAGGTTCCTGGTC TGACCAAACATATCCAGAAGGCACCCAGGCTATCTATAAATGCCGCCCTGGATATAGATC TCTTGGAAATATAATAATGGTATGCAGGAAGGGAGAATGGGTTGCTCTTAATCCATTAAG GAAATGTCAGAAAAGGCCCTGTGGACATCCTGGAGATACTCCTTTTGGTACTTTTACCCT TACAGGAGGAAATGTGTTTGAATATGGTGTAAAAGCTGTGTATACATGTAATGAGGGGTA TCAATTGCTAGGTGAGATTAATTACCGTGAATGTGACACAGATGGATGGACCAATGATAT TCCTATATGTGAAGTTGTGAAGTGTTTACCAGTGACAGCACCAGAGAATGGAAAAATTGT CAGTAGTGCAATGGAACCAGATCGGGAATACCATTTTGGACAAGCAGTACGGTTTGTATG TAACTCAGGCTACAAGATTGAAGGAGATGAAGAAATGCATTGTTCAGACGATGGTTTTTG GAGTAAAGAGAAACCAAAGTGTGTGGAAATTTCATGCAAATCCCCAGATGTTATAAATGG ATCTCCTATATCTCAGAAGATTATTTATAAGGAGAATGAACGATTTCAATATAAATGTAA CATGGGTTATGAATACAGTGAAAGAGGAGATGCTGTATGCACTGAATCTGGATGGCGTCC GTTGCCTTCATGTGAAGAAAAATCATGTGATAATCCTTATATTCCAAATGGTGACTACTC ACCTTTAAGGATTAAACACAGAACTGGAGATGAAATCACGTACCAGTGTAGAAATGGTTT TTATCCTGCAACCCGGGGAAATACAGCCAAATGCACAAGTACTGGCTGGATACCTGCTCC GAGATGTACCTTGAAACCTTGTGATTATCCAGACATTAAACATGGAGGTCTATATCATGA GAATATGCGTAGACCATACTTTCCAGTAGCTGTAGGAAAATATTACTCCTATTACTGTGA TGAACATTTTGAGACTCCGTCAGGAAGTTACTGGGATCACATTCATTGCACACAAGATGG ATGGTCGCCAGCAGTACCATGCCTCAGAAAATGTTATTTTCCTTATTTGGAAAATGGATA TAATCAAAATTATGGAAGAAAGTTTGTACAGGGTAAATCTATAGACGTTGCCTGCCATCC TGGCTACGCTCTTCCAAAAGCGCAGACCACAGTTACATGTATGGAGAATGGCTGGTCTCC TACTCCCAGATGCATCCGTGTCAAAACATGTTCCAAATCAAGTATAGATATTGAGAATGG GTTTATTTCTGAATCTCAGTATACATATGCCTTAAAAGAAAAAGCAAAATATCAATGCAA ACTAGGATATGTAACAGCAGATGGTGAAACATCAGGATCAATTACATGTGGGAAAGATGG ATGGTCAGCTCAACCCACGTGCATTAAATCTTGTGATATCCCAGTATTTATGAATGCCAG AACTAAAAATGACTTCACATGGTTTAAGCTGAATGACACATTGGACTATGAATGCCATGA TGGTTATGAAAGCAATACTGGAAGCACCACTGGTTCCATAGTGTGTGGTTACAATGGTTG GTCTGATTTACCCATATGTTATGAAAGAGAATGCGAACTTCCTAAAATAGATGTACACTT AGTTCCTGATCGCAAGAAAGACCAGTATAAAGTTGGAGAGGTGTTGAAATTCTCCTGCAA ACCAGGATTTACAATAGTTGGACCTAATTCCGTTCAGTGCTACCACTTTGGATTGTCTCC TGACCTCCCAATATGTAAAGAGCAAGTACAATCATGTGGTCCACCTCCTGAACTCCTCAA TGGGAATGTTAAGGAAAAAACGAAAGAAGAATATGGACACAGTGAAGTGGTGGAATATTA TTGCAATCCTAGATTTCTAATGAAGGGACCTAATAAAATTCAATGTGTTGATGGAGAGTG GACAACTTTACCAGTGTGTATTGTGGAGGAGAGTACCTGTGGAGATATACCTGAACTTGA ACATGGCTGGGCCCAGCTTTCTTCCCCTCCTTATTACTATGGAGATTCAGTGGAATTCAA TTGCTCAGAATCATTTACAATGATTGGACACAGATCAATTACGTGTATTCATGGAGTATG GACCCAACTTCCCCAGTGTGTGGCAATAGATAAACTTAAGAAGTGCAAATCATCAAATTT AATTATACTTGAGGAACATTTAAAAAACAAGAAGGAATTCGATCATAATTCTAACATAAG GTACAGATGTAGAGGAAAAGAAGGATGGATACACACAGTCTGCATAAATGGAAGATGGGA TCCAGAAGTGAACTGCTCAATGGCACAAATACAATTATGCCCACCTCCACCTCAGATTCC CAATTCTCACAATATGACAACCACACTGAATTATCGGGATGGAGAAAAAGTATCTGTTCT TTGCCAAGAAAATTATCTAATTCAGGAAGGAGAAGAAATTACATGCAAAGATGGAAGATG GCAGTCAATACCACTCTGTGTTGAAAAAATTCCATGTTCACAACCACCTCAGATAGAACA CGGAACCATTAATTCATCCAGGTCTTCACAAGAAAGTTATGCACATGGGACTAAATTGAG TTATACTTGTGAGGGTGGTTTCAGGATATCTGAAGAAAATGAAACAACATGCTACATGGG AAAATGGAGTTCTCCACCTCAGTGTGAAGGCCTTCCTTGTAAATCTCCACCTGAGATTTC TCATGGTGTTGTAGCTCACATGTCAGACAGTTATCAGTATGGAGAAGAAGTTACGTACAA ATGTTTTGAAGGTTTTGGAATTGATGGGCCTGCAATTGCAAAATGCTTAGGAGAAAAATG GTCTCACCCTCCATCATGCATAAAAACAGATTGTCTCAGTTTACCTAGCTTTGAAAATGC CATACCCATGGGAGAGAAGAAGGATGTGTATAAGGCGGGTGAGCAAGTGACTTACACTTG TGCAACATATTACAAAATGGATGGAGCCAGTAATGTAACATGCATTAATAGCAGATGGAC AGGAAGGCCAACATGCAGAGACACCTCCTGTGTGAATCCGCCCACAGTACAAAATGCTTA TATAGTGTCGAGACAGATGAGTAAATATCCATCTGGTGAGAGAGTACGTTATCAATGTAG GAGCCCTTATGAAATGTTTGGGGATGAAGAAGTGATGTGTTTAAATGGAAACTGGACGGA ACCACCTCAATGCAAAGATTCTACAGGAAAATGTGGGCCCCCTCCACCTATTGACAATGG GGACATTACTTCATTCCCGTTGTCAGTATATGCTCCAGCTTCATCAGTTGAGTACCAATG CCAGAACTTGTATCAACTTGAGGGTAACAAGCGAATAACATGTAGAAATGGACAATGGTC AGAACCACCAAAATGCTTACATCCGTGTGTAATATCCCGAGAAATTATGGAAAATTATAA CATAGCATTAAGGTGGACAGCCAAACAGAAGCTTTATTCGAGAACAGGTGAATCAGTTGA ATTTGTGTGTAAACGGGGATATCGTCTTTCATCACGTTCTCACACATTGCGAACAACATG TTGGGATGGGAAACTGGAGTATCCAACTTGTGCAAAAAGATAGAATCAATCATAAAGTGC ACACCTTTATTCAGAACTTTAGTATTAAATCAGTTCTCAATTTCATTTTTTATGTATTGT TTTACTCCTTTTTATTCATACGTAAAATTTTGGATTAATTTGTGAAAATGTAATTATAAG CTGAGACCGGTGGCTCTCTTCTTAAAAGCACCATATTAAATCCTGGAAAACTAAAAAAAA AAAAAAAAAACTCGAC >OriGene 5' read for NM_000186 unedited
TACGACTCCTATAGGGCGGCCGCGATTCGGCACGAGGGGACGTTGTGAACAGAGTTAGCT GGTAAATGTCCTCTTAAAAGATCCAAAAAATGAGACTTCTAGCAAAGATTATTTGCCTTA TGTTATGGGCTATTTGTGTAGCAAAAGATTGCAATGAACTTCCTCCAAGAAGAAATACAG AAATTCTGACAGGTTCCTGGTCTGACCAAACATATCCAGAAGGCACCCAGGCTATCTATA AATGCCGCCCTGGATATAGATCTCTTGGAAATATAATAATGGTATGCAGGAAGGGAGAAT GGGTTGCTCTTAATCCATTAAGGAAATGTCAGAAAAGGCCCTGTGGACATCCTGGAGATA CTCCTTTTGGTACTTTTACCCTTACAGGAGGAAATGTGTTTGAATATGGTGTAAAAGCTG TGTATACATGTAATGAGGGGTATCAATTGCTAGGTGAGATTAATTACCGTGAATGTGACA CAGATGGATGGACCAATGATATTCCTATATGTGAAGTTGTGAAGTGTTTACCAGTGACAG CACCAGAGAATGGAAAAATTGTCAGTAGTGCAATGGAACCAGATCGGGAATACCATTTTG GACAAGCAGTACGGTTTGTATGTAAACTCAGGCTACAGATTGAAGGAGATGAAGAAATGC ATTGNTCAGACGATGTTTTTTGGAGTAAAGAGAAACANAGTGTGTGGAAATTCATGCACA TCCCAGATGTTATAATGGATCTCCTATATCTCAGAAGATTATTATAGGAGAATGAACGAT TTCATATAAATGTACATGGGTTATGAATACAGTGAAAGAGAGATGCTGTATGCACTGAAC TGGATGGCGCCGTTGCCTTCTGTGAAGAAAATATGTGATATCCTTATTTCAAAGGTGACT ACTACCTTAAGGTTAACACGACTGAGAGAAATCCCACAGTGTAAAATGTTTCTCCTGCAC CG >OriGene 3' read for NM_000186 unedited
NTTTACTTTGNNACCGCGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTAGTTT TCCAGGATTTAATATGGTGCTTTTAAGAAGAGAGCCACCGGTCTCAGCTTATAATTACAT TTTCACAAATTAATCCAAAATTTTACGTATGAATAAAAAGGAGTAAAACAATACATAAAA AATGAAATTGAGAACTGATTTAATACTAAAGTTCTGAATAAAGGTGTGCACTTTATGATT GATTCTATCTTTTTGCACAAGTTGGATACTCCAGTTTCCCATCCCAACATGTTGTTCGCA ATGTGTGAGAACGTGATGAAAGACGATATCCCCGTTTACACACAAATTCAACTGATTCAC CTGTTCTCGAATAAAGCTTCTGTTTGGCTGTCCACCTTAATGCTATGTTATAATTTTCCA TAATTTCTCGGGATATTACACACGGATGTAAGCATTTTGGTGGTTCTGACCATTGTCCAT TTCTACATGTTATTCGCTTGTTACCCTCAAGTTGATACAAGTTCTGGCATTGGTACTCAA CTGATGAAGCTGGAGCATATACTGACAACGGGAATGAAGTAATGTCCCCATTGTCAATAG GTGGAGGGGGCCCACATTTTCCTGTAGAATCTTTGCATTGAGGTGGTTCCGTCCAGTTTC CATTTAAACACATCACTTTCTCATCCCCAAACATTTCATAAGGGCCTCCTACATTGATAA CGTACTCTCTTACACAAGGATATTTACTTATCTGTCTCGACACTATATAAGCATTTTGTA CTGGTGGCGGATTCACACAGGAGTTGCTTTTGAATGTGGCCTTCCTGTCCATCTGTATTA ATGCATGTACATTACTGGCTTCATCCATTTGAAAATTGTGGACAAGGGTAAGTACTTGTT CCCCCGCTTTAAACATCCTCTTTTTTCCA |
| Restriction Sites | NotI-NotI |
| ACCN | NM_000186 |
| Insert Size | 4000 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_000186.2, NP_000177.2 |
| RefSeq Size | 4004 bp |
| RefSeq ORF | 3696 bp |
| Locus ID | 3075 |
| UniProt ID | P08603 |
| Domains | CCP |
| Protein Families | Druggable Genome, Secreted Protein |
| Protein Pathways | Complement and coagulation cascades |
| Gene Summary | This gene is a member of the Regulator of Complement Activation (RCA) gene cluster and encodes a protein with twenty short consensus repeat (SCR) domains. This protein is secreted into the bloodstream and has an essential role in the regulation of complement activation, restricting this innate defense mechanism to microbial infections. Mutations in this gene have been associated with hemolytic-uremic syndrome (HUS) and chronic hypocomplementemic nephropathy. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Oct 2011] Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (a). |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC220707 | CFH (Myc-DDK-tagged)-Human complement factor H (CFH), transcript variant 1 |
CNY 13,712.00 |
|
| RC220707L3 | Lenti-ORF clone of CFH (Myc-DDK-tagged)-Human complement factor H (CFH), transcript variant 1 |
CNY 14,160.00 |
|
| RC220707L4 | Lenti-ORF clone of CFH (mGFP-tagged)-Human complement factor H (CFH), transcript variant 1 |
CNY 16,112.00 |
|
| RG220707 | CFH (tGFP-tagged) - Human complement factor H (CFH), transcript variant 1 |
CNY 15,312.00 |
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