MTMR6 (NM_004685) Human Untagged Clone

Name: MTMR6 (NM_004685) Human Untagged Clone
SKU: SC128024
Price: 7220.00

CAT＃: SC128024

MTMR6 (untagged)-Human myotubularin related protein 6 (MTMR6)

Datasheet

SDS

"NM_004685" in other vectors (6)

SC128024 is the updated version of SC128025.

CNY 7,220.00

货期*

5周

规格

Product images

经常一起买 (4)

TF81001

TurboFectin Transfection Reagent (1 mL in 1 vial)

CNY 4,090.00

CC100003

DH5α Chemically Competent Cells (≥10^8 cfu/μg of pUC19 DNA)

CNY 1,280.00

PRIMER

Forward sequencing primer VP1.5, Reverse sequencing primer XL39, 100pmoles each

CNY 480.00

TA378761

MTMR6 Rabbit polyclonal Antibody

CNY 1,999.00
CNY 3,280.00

Specifications

Product Data
Type	Human Untagged Clone
Tag	Tag Free
Vector	pCMV6-XL5
E. coli Selection	Ampicillin (100 ug/mL)
Mammalian Cell Selection	None
Sequence Data	Fully Sequenced ORF (showhide) >NCBI ORF sequence for NM_004685, the custom clone sequence may differ by one or more nucleotides ATGGAGCATATCCGGACGACCAAGGTCGAACAAGTAAAATTACTTGACCGATTCAGTACCAGCAACAAGT CATTAACAGGAACACTGTATCTTACGGCTACACATCTATTATTTATCGACTCTCATCAAAAAGAAACCTG GATATTACACCACCATATTGCCTCAGTAGAGAAACTTGCTTTGACTACTTCTGGATGCCCCCTTGTGATA CAGTGCAAGAACTTCAGAACTGTGCATTTCATTGTTCCCAGAGAAAGAGATTGCCATGATATTTACAACT CTTTGCTACAACTGTCAAAACAAGCAAAATATGAAGATCTCTATGCATTTTCTTATAATCCCAAACAAAA TGATTCAGAACGACTACAAGGCTGGCAGCTCATTGATCTCGCTGAGGAATATAAGAGGATGGGAGTGCCA AACTCACACTGGCAGTTGTCTGATGCCAACCGGGACTACAAGATTTGTGAAACTTACCCCAGAGAACTTT ATGTTCCCCGGATAGCAAGCAAACCAATAATTGTTGGTAGTTCCAAGTTCCGGAGCAAGGGAAGATTCCC AGTTCTTTCCTACTATCATCAAGATAAGGAGGCTGCCATTTGTCGATGTAGTCAGCCACTCTCTGGATTC AGTGCCAGGTGCCTGGAGGATGAACATTTGCTTCAAGCCATTAGTAAAGCCAATCCAGTCAATCGCTATA TGTACGTCATGGATACCAGGCCAAAACTGAATGCAATGGCCAACAGAGCAGCTGGAAAAGGTTATGAAAA TGAAGACAACTATTCCAATATTAGATTTCAGTTTGTTGGAATTGAAAATATTCATGTCATGAGGTCCAGC CTTCAGAAATTATTGGAAGTCAATGGCACTAAAGGGCTTTCTGTCAATGATTTCTACTCCGGTTTGGAGA GCTCGGGATGGCTTCGCCATATCAAAGCTGTTATGGATGCTGCAATCTTCTTGGCCAAAGCAATAACAGT TGAAAATGCAAGTGTGTTGGTGCATTGTTCCGATGGTTGGGATAGGACTTCCCAGGTTTGTTCCCTGGGT TCTCTTTTATTGGATTCCTACTACAGGACAATCAAAGGATTCATGGTTTTAATAGAAAAGGATTGGATCT CTTTTGGACATAAATTTTCAGAGAGGTGTGGCCAGTTGGATGGTGACCCAAAGGAAGTCTCACCAGTGTT TACTCAGTTCTTGGAATGTGTGTGGCATTTGACCGAACAGTTTCCACAAGCCTTTGAATTCAGTGAAGCA TTTCTTCTTCAGATCCATGAGCATATTCATTCATGCCAGTTTGGAAACTTCCTTGGAAATTGTCAGAAGG AAAGAGAAGAGCTCAAGTTGAAGGAGAAGACTTATTCCCTGTGGCCATTTCTTTTGGAAGACCAAAAGAA GTACTTAAATCCTCTCTACAGTTCCGAATCTCACAGATTTACAGTTTTGGAGCCAAATACAGTATCTTTC AATTTTAAGTTTTGGAGGAACATGTACCATCAATTTGATCGAACACTGCATCCTAGGCAGTCTGTATTTA ATATAATTATGAATATGAATGAGCAAAATAAACAATTAGAGAAAGATATTAAAGACCTAGAATCTAAAAT TAAACAACGCAAAAATAAGCAAACAGATGGCATCCTCACCAAGGAATTGTTACATTCAGTTCATCCTGAA TCACCTAACCTCAAAACTTCCCTGTGTTTTAAAGAGCAGACTCTGCTACCCGTAAATGATGCTCTTCGAA CTATAGAGGGCAGCAGCCCGGCAGATAATCGTTATAGTGAATATGCAGAAGAGTTTTCTAAATCAGAACC TGCTGTGGTCAGCTTAGAGTATGGTGTGGCAAGAATGACTTGTTAG 5' Read Nucleotide Sequence (showhide) >OriGene 5' read for NM_004685 unedited TTTCTTATAGGGNNCGGCCGAGAACTTCGGCACGAGGGCTGCCGGCTGACGTCTCCTTGC GATGGAGCATATCCGGACGACCAAGGTCGAACAAGTAAAATTACTTGACCGATTCAGTAC CAGCAACAAGTCATTAACAGGAACACTGTATCTTACGGCTACACATCTATTATTTATCGA CTCTCATCAAAAAGAAACCTGGATATTTCACCACCATATTGCCTCAGTAGAGAAACTTGC TTTGACTACTTCTGGATGCCCCCTTGTGATACAGTGCAAGAACTTCAGAACTGTGCATTT CATTGTTCCCAGAGAAAGAGATTGCCATGATATTTACAACTCTTTGCTACAACTGTCAAA ACAAGCAAAATATGAAGATCTCTATGCATTTTCTTATAATCCCAAACAAAATGATTCAGA ACGACTACAAGGCTGGCAGCTCATTGATCTCGCTGAGGAATATAAGAGGATGGGAGTGCC AAACTCACACTGGCAGTTGTCTGATGCCAACCGGGACTACAAGATTTGTGAAACTTACCC CAGAGAACTTTATGTTCCCCGGATAGCAAGCAAACCAATAATTGTTGGTAGTTCCAAGTT CCGGAGCAAGGGAAGATTCCCAGTTCTTTCCTACTATCATCAAGATAAGGAGGCTGCCAT TTGTCGATGTAGTCAGCCACTCTCTGGATNCAGTGCCANGTGCCTGGAGGATGAACATTT GCTTCAGCCATTTAGTAAGCCAATCCAGTCAATCGCTATATGTACGTCATGGATACCANG CCANNAACTGATGCAATGGCCANCAGAGCAGCTGGAANAGGNNTATGAAATGAAGACCAC TATTCCCATATAGATTTCAGTTGGGTGGAATGAAAATATNCTGCCATGAGGGTCAGCCTC AAAANTATTGGAGTCATGGCCTAAGGGCTTNTGTCATGATNCTACTCGGNTGGAAGCTCG GGATGCTCGCATACAGCTGTATGGAGCTGCAGCTCTTGCCAGCATACAGTGAAATGCAGG TGGTGTGCATGTTCGAGGT 3' Read Nucleotide Sequence (showhide) >OriGene 3' read for NM_004685 unedited AATATTTGNCCGCGGCCGCATTCTANGATCGGTTTTTTTTTTTTTTTTTTTTTTTTTTTT TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTGGGGCCCCTTTGGTTTATCCCAAAAAAA AACCTTCAAAGGAAAAGGGGAACCTTTAATTACCTTTAAATCATATTTGAAAAAATTTAC ATGGTTTACCCTTCCAAACCCCCTGAACATAAATTCAACTTTTTAAAAAATATACCCAGG TTGGTTTTGGCAACATAAACCCTGGGGGGCACTTAAAAAGGAACTGGTTTTTCAACCCCC CTGGGGGCATATAAACCCCCAAATGTTTGTTTGAAGTTGAAAATTAAAAAAATAAACCCG AGTTGAATCCCAAAAGTCCGCCCCAAAAAATTTTAAAACCCCAATCAGGGGCGGGAACCC CAAGGGCCAAAAACTTCCCTTTGGAGTCACAAAAATTAAATTTCCATTCCCAGGGCTTAA ATATGGAAGCAGGATTGGGTAAACACAAACTATTTTTTATAGGGCATTTTTGGGGGTGGT TAAAAAGGAAAATTTTTTAAATTACCTAAGGGTTTACAAAAAAGCCTTGGAAAAATAAAC CGGGTAAAAAAAGCTCTCATACAAAAAAGGTTTTTTTGGGCTGAAAAAAAAGTTTATTTT CAAAACTAATATAATAAAGGGGTAACAAAAAGTTCCCTGGGGAACACTTTGCAAATTGCC TAATACTCGAATTGGACTTCATGCCACCATGGTATTTAAATTTTCAATTTTAAAGCCCGT TGGGTGAAATTGCTAATTCCAGGGATAGTTGGGGGGTTTAAAAGGGTTGGGTCCTGGGTT TTGGGGAATTAAAGATATGGCCTGTACCCAGAATAAACAGTAATATACATGGCAAATGAA TCTTCCCAAAATTAATGTGCCTTTTGTTAACAGAACCTTGACTAAA
Restriction Sites	NotI-NotI
ACCN	NM_004685
Insert Size	4100 bp
OTI Disclaimer	Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components	The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution	1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq	NM_004685.2, NP_004676.2
RefSeq Size	4201 bp
RefSeq ORF	1866 bp
Locus ID	9107
UniProt ID	Q9Y217
Domains	PTPc_motif
Protein Families	Druggable Genome, Phosphatase
Protein Pathways	Fructose and mannose metabolism, Metabolic pathways, Riboflavin metabolism, Thiamine metabolism
Gene Summary	Phosphatase that acts on lipids with a phosphoinositol headgroup (PubMed:19038970, PubMed:22647598). Dephosphorylates phosphatidylinositol 3-phosphate (PtdIns(3)P) and phosphatidylinositol 3,5-bisphosphate (PubMed:19038970, PubMed:22647598) (Probable). Binds with high affinity to phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2) but also to phosphatidylinositol 3-phosphate (PtdIns(3)P), phosphatidylinositol 4-phosphate (PtdIns(4)P), and phosphatidylinositol 5-phosphate (PtdIns(5)P), phosphatidic acid and phosphatidylserine (PubMed:19038970). Negatively regulates ER-Golgi protein transport (By similarity). Probably in association with MTMR9, plays a role in the late stages of macropinocytosis by dephosphorylating phosphatidylinositol 3-phosphate in membrane ruffles (PubMed:24591580). Acts as a negative regulator of KCNN4/KCa3.1 channel activity in CD4(+) T-cells possibly by decreasing intracellular levels of phosphatidylinositol 3-phosphate (PubMed:15831468). Negatively regulates proliferation of reactivated CD4(+) T-cells (PubMed:16847315). In complex with MTMR9, negatively regulates DNA damage-induced apoptosis (PubMed:19038970, PubMed:22647598). The formation of the MTMR6-MTMR9 complex stabilizes both MTMR6 and MTMR9 protein levels (PubMed:19038970).[UniProtKB/Swiss-Prot Function]

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

Documents

Product Manuals
TrueORFs: Open Reading Frame Clones - 10 ug in PrecisionShuttle Vector System pLenti-ORF destination vector Transfection - TurboFectin 8.0 Transfection Reagent Plasmid Preparation - PowerPrep Plasmid Purification Kits
FAQs
TrueORF Clones/PrecisionShuttle Organelle Marker Transfection Reagent
SDS
TrueORF SDS

Resources

cDNA 克隆相关资源
Video Tutorial: Clone Selection Guide Product Video: What is TrueORF GOLD and why it is the most popular type of clone Video Tutorial: How to make Lentivirus particles Video Tutorial: Is the Lentivirus Safe Product Brochure: cDNA clones $98 Clones. Download the List of 15,000 Protocol: Lentivirus packaging

Other Versions

SKU	Description	Size	Price
RC208069	MTMR6 (Myc-DDK-tagged)-Human myotubularin related protein 6 (MTMR6)	10 ug 产品选项验证失败所有选项都是必需的	CNY 4,560.00
RC208069L1	Lenti ORF clone of Human myotubularin related protein 6 (MTMR6), Myc-DDK-tagged	10 ug 产品选项验证失败所有选项都是必需的	CNY 6,460.00
RC208069L2	Lenti ORF clone of Human myotubularin related protein 6 (MTMR6), mGFP tagged	10 ug 产品选项验证失败所有选项都是必需的	CNY 6,460.00
RC208069L3	Lenti ORF clone of Human myotubularin related protein 6 (MTMR6), Myc-DDK-tagged	10 ug 产品选项验证失败所有选项都是必需的	CNY 6,460.00
RC208069L4	Lenti ORF clone of Human myotubularin related protein 6 (MTMR6), mGFP tagged	10 ug 产品选项验证失败所有选项都是必需的	CNY 6,460.00
RG208069	MTMR6 (tGFP-tagged) - Human myotubularin related protein 6 (MTMR6)	10 ug 产品选项验证失败所有选项都是必需的	CNY 5,040.00

其它MTMR6产品

Expression Plasmids

Lentiviral Particles

CRISPR

RNAi

Proteins

Antibodies