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CLDN16 (NM_006580) Human Untagged Clone
CAT＃: SC303793
CLDN16 (untagged)-Human claudin 16 (CLDN16)
CNY 2,400.00
CNY 6,270.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | HOMG3; PCLN1 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene sequence for NM_006580 edited
CCCCACCCGAAACACACTCAGCCCTTGCACTGACCTGCCTTCTGATTGGAGGCTGGTTGC TTCGGATAATGACCTCCAGGACCCCACTGTTGGTTACAGCCTGTTTGTATTATTCTTACT GCAACTCAAGACACCTGCAGCAGGGCGTGAGAAAAAGTAAAAGACCAGTATTTTCACATT GCCAGGTACCAGAAACACAGAAGACTGACACCCGCCACTTAAGTGGGGCCAGGGCTGGTG TCTGCCCATGTTGCCATCCTGATGGGCTGCTTGCCACAATGAGGGATCTTCTTCAATACA TCGCTTGCTTCTTTGCCTTTTTCTCTGCTGGGTTTTTGATTGTGGCCACCTGGACTGACT GTTGGATGGTGAATGCTGATGACTCTCTGGAGGTGAGCACAAAATGCCGAGGCCTCTGGT GGGAATGCGTCACAAATGCTTTTGATGGGATTCGCACCTGTGATGAGTACGATTCCATAC TTGCGGAGCATCCCTTGAAGCTGGTGGTAACTCGAGCGTTGATGATTACTGCAGATATTC TAGCTGGGTTTGGATTTCTCACCCTGCTCCTTGGTCTTGACTGCGTGAAATTCCTCCCTG ATGAGCCGTACATTAAAGTCCGCATCTGCTTTGTTGCTGGAGCCACGTTACTAATAGCAG GTACCCCAGGAATCATTGGCTCTGTGTGGTATGCTGTTGATGTGTATGTGGAACGTTCTA CTTTGGTTTTGCACAATATATTTCTTGGTATCCAATATAAATTTGGTTGGTCCTGTTGGC TCGGAATGGCTGGGTCTCTGGGTTGCTTTTTGGCTGGAGCTGTTCTCACCTGCTGCTTAT ATCTTTTTAAAGATGTTGGACCTGAGAGAAACTATCCTTATTCCTTGAGGAAAGCCTATT CAGCCGCGGGTGTTTCCATGGCCAAGTCATACTCAGCCCCTCGCACAGAGACGGCCAAAA TGTATGCTGTAGACACAAGGGTGTAAAATGCACGTTTCAGGGTGTGTTTGCATATGATTT AATCAATCAGTATGGTTACATTGATAAAATAGTAAGTCAATCCAGGAACAGTTATTTAGA ATTCATATTGAATTAAATTAATTGCTAGCTTAATCAAAATGTTTGATTCTCCTATACTTT TTCTTTCTATTACTCTTATATTTTCCCGTCATTCTCTCTGCTAACCTTCCACCTTATGCA CACACTTTCCCTATATTTTAAGATAAGTCTGCTAGGATGTAGAAATATTTGTTTGTGATT TCTATATAGCTATTAGAGATTATGACATAGTAATATTAAAATGAAATGATACTTAAACAG AAAGCAATTTCCAAAGAGGCCAGGGACCCTAATCTTTGAAGAGATGAAGAAACTTACTTT TCTCCCTGGCTTTTGGTTCACTTTTTGTA |
| Restriction Sites | Please inquire |
| ACCN | NM_006580 |
| Insert Size | 1400 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | The ORF of this clone has been fully sequenced and found to be a perfect match to NM_006580.2. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_006580.2, NP_006571.1 |
| RefSeq Size | 1494 bp |
| RefSeq ORF | 918 bp |
| Locus ID | 10686 |
| UniProt ID | Q9Y5I7 |
| Protein Families | Druggable Genome, Transmembrane |
| Protein Pathways | Cell adhesion molecules (CAMs), Leukocyte transendothelial migration, Tight junction |
| Gene Summary | Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. It is found primarily in the kidneys, specifically in the thick ascending limb of Henle, where it acts as either an intercellular pore or ion concentration sensor to regulate the paracellular resorption of magnesium ions. Defects in this gene are a cause of primary hypomagnesemia, which is characterized by massive renal magnesium wasting with hypomagnesemia and hypercalciuria, resulting in nephrocalcinosis and renal failure. This gene and the CLDN1 gene are clustered on chromosome 3q28. [provided by RefSeq, Jun 2010] |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC210216 | CLDN16 (Myc-DDK-tagged)-Human claudin 16 (CLDN16) |
CNY 2,400.00 |
|
| RC210216L1 | Lenti ORF clone of Human claudin 16 (CLDN16), Myc-DDK-tagged |
CNY 4,800.00 |
|
| RC210216L2 | Lenti ORF clone of Human claudin 16 (CLDN16), mGFP tagged |
CNY 5,890.00 |
|
| RC210216L3 | Lenti ORF clone of Human claudin 16 (CLDN16), Myc-DDK-tagged |
CNY 4,800.00 |
|
| RC210216L4 | Lenti ORF clone of Human claudin 16 (CLDN16), mGFP tagged |
CNY 4,800.00 |
|
| RG210216 | CLDN16 (tGFP-tagged) - Human claudin 16 (CLDN16) |
CNY 4,000.00 |
