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CD105 (ENG) (NM_001114753) Human Untagged Clone
CAT＃: SC318963
ENG (untagged)-Human endoglin (ENG), transcript variant 1
CNY 7,360.00
Product images
CNY 1,999.00
CNY 2,700.00
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | END; HHT1; ORW1 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>NCBI ORF sequence for NM_001114753, the custom clone sequence may differ by one or more nucleotides
ATGGACCGCGGCACGCTCCCTCTGGCTGTTGCCCTGCTGCTGGCCAGCTGCAGCCTCAGCCCCACAAGTC TTGCAGAAACAGTCCATTGTGACCTTCAGCCTGTGGGCCCCGAGAGGGGCGAGGTGACATATACCACTAG CCAGGTCTCGAAGGGCTGCGTGGCTCAGGCCCCCAATGCCATCCTTGAAGTCCATGTCCTCTTCCTGGAG TTCCCAACGGGCCCGTCACAGCTGGAGCTGACTCTCCAGGCATCCAAGCAAAATGGCACCTGGCCCCGAG AGGTGCTTCTGGTCCTCAGTGTAAACAGCAGTGTCTTCCTGCATCTCCAGGCCCTGGGAATCCCACTGCA CTTGGCCTACAATTCCAGCCTGGTCACCTTCCAAGAGCCCCCGGGGGTCAACACCACAGAGCTGCCATCC TTCCCCAAGACCCAGATCCTTGAGTGGGCAGCTGAGAGGGGCCCCATCACCTCTGCTGCTGAGCTGAATG ACCCCCAGAGCATCCTCCTCCGACTGGGCCAAGCCCAGGGGTCACTGTCCTTCTGCATGCTGGAAGCCAG CCAGGACATGGGCCGCACGCTCGAGTGGCGGCCGCGTACTCCAGCCTTGGTCCGGGGCTGCCACTTGGAA GGCGTGGCCGGCCACAAGGAGGCGCACATCCTGAGGGTCCTGCCGGGCCACTCGGCCGGGCCCCGGACGG TGACGGTGAAGGTGGAACTGAGCTGCGCACCCGGGGATCTCGATGCCGTCCTCATCCTGCAGGGTCCCCC CTACGTGTCCTGGCTCATCGACGCCAACCACAACATGCAGATCTGGACCACTGGAGAATACTCCTTCAAG ATCTTTCCAGAGAAAAACATTCGTGGCTTCAAGCTCCCAGACACACCTCAAGGCCTCCTGGGGGAGGCCC GGATGCTCAATGCCAGCATTGTGGCATCCTTCGTGGAGCTACCGCTGGCCAGCATTGTCTCACTTCATGC CTCCAGCTGCGGTGGTAGGCTGCAGACCTCACCCGCACCGATCCAGACCACTCCTCCCAAGGACACTTGT AGCCCGGAGCTGCTCATGTCCTTGATCCAGACAAAGTGTGCCGACGACGCCATGACCCTGGTACTAAAGA AAGAGCTTGTTGCGCATTTGAAGTGCACCATCACGGGCCTGACCTTCTGGGACCCCAGCTGTGAGGCAGA GGACAGGGGTGACAAGTTTGTCTTGCGCAGTGCTTACTCCAGCTGTGGCATGCAGGTGTCAGCAAGTATG ATCAGCAATGAGGCGGTGGTCAATATCCTGTCGAGCTCATCACCACAGCGGAAAAAGGTGCACTGCCTCA ACATGGACAGCCTCTCTTTCCAGCTGGGCCTCTACCTCAGCCCACACTTCCTCCAGGCCTCCAACACCAT CGAGCCGGGGCAGCAGAGCTTTGTGCAGGTCAGAGTGTCCCCATCCGTCTCCGAGTTCCTGCTCCAGTTA GACAGCTGCCACCTGGACTTGGGGCCTGAGGGAGGCACCGTGGAACTCATCCAGGGCCGGGCGGCCAAGG GCAACTGTGTGAGCCTGCTGTCCCCAAGCCCCGAGGGTGACCCGCGCTTCAGCTTCCTCCTCCACTTCTA CACAGTACCCATACCCAAAACCGGCACCCTCAGCTGCACGGTAGCCCTGCGTCCCAAGACCGGGTCTCAA GACCAGGAAGTCCATAGGACTGTCTTCATGCGCTTGAACATCATCAGCCCTGACCTGTCTGGTTGCACAA GCAAAGGCCTCGTCCTGCCCGCCGTGCTGGGCATCACCTTTGGTGCCTTCCTCATCGGGGCCCTGCTCAC TGCTGCACTCTGGTACATCTACTCGCACACGCGTTCCCCCAGCAAGCGGGAGCCCGTGGTGGCGGTGGCT GCCCCGGCCTCCTCGGAGAGCAGCAGCACCAACCACAGCATCGGGAGCACCCAGAGCACCCCCTGCTCCA CCAGCAGCATGGCATAG >OriGene 5' read for NM_001114753 unedited
TTGGATTTTGTAATACGACTCACTATAGGGCGGGCCGCGAATCGGCACGAGGGCCGGCCG GGCTGGATGAGCCGGGAGCTCCCTGCTGCCGGTCATACCACAGCCTTCATCTGCGCCCTG GGGCCAGGACTGCTGCTGTCACTGCCATCCATTGGAGCCCAGCACCCCCTCCCCGCCCAT CCTTCGGACAGCAACTCCAGCCCAGCCCCGCGTCCCTGTGTCCACTTCTCCTGACCCCTC GGCCGCCACCCCAGAAGGCTGGAGCAGGGACGCCGTCGCTCCGGCCGCCTGCTCCCCTCG GGTCCCCGTGCGAGCCCACGCCGGCCCCGGTGCCCGCCCGCAGCCCTGCCACTGGACACA GGATAAGGCCCAGCGCACAGGCCCCCACGTGGACAGCATGGACCGCGGCACGCTCCCTCT GGCTGTTGCCCTGCTGCTGGCCAGCTGCAGCCTCAGCCCCACAAGTCTTGCAGAAACAGT CCATTGTGACCTTCAGCCTGTGGGCCCCGAGAGGGGCGAGGTGACATATACCACTAGCCA GGTCTCGAAGGGCTGCGTGGCTCAGGCCCCCAATGCCATCCTTTGAAGTCCATGTCCTCT TCCTAGAGTTCCCAACGGGCCCGTCACAGCTNGGAGCTGACTCTCCAGGCATCCAAGCAA AATGGCACCTGCCCCCGAGAGGGGCCTTCTGGNCCTCAGTGTAAACAACAAGTGTCTTCC TGCATCTCCAGGCCCTGGGAATCCCACTGCACTTGGCCTACAATTTCAGCCTGGTCACCT TCCAGACCCCCCGGGGGGTAACACCACAGAGCTGGCATCCTTCCCAAGACCAATCCTTTG AGTGGGCAGTTGAGGAG >OriGene 3' read for NM_001114753 unedited
GCCGCCTCTAAAGTGAGTTTTTTTTTTTTTTTTTTGGTTTCATGGTCTGATTTATTGGTG GTGAATACACAGGGGCAGGCCCAGGACAAGCAGCTTGGCTACTCCCCCTCTGCTGGCTGC CCGACCGGCAGAGGGGGCTCCATGTGGCAGGAGCTAGGCTCCCAACGCCCACTGTTCTTG CCACCCTCTGGGCTCCCATGCTGGGCTCCGCTAGGCTCCTGTCTCCCCTGCCAGTTAGTT AGGCAAGTTCAGGTGTGGAGGCCGCAGGGATAGATCCAGGTGGCTCTGGGCTGGGCCCTC TTCTCTTCCCAGCGGGGAGGTGCTGTTGGCCTGGCTGGGCTGGCCTGAATCTGTTTCAAG TTCTCCCTTCCTGCCCAGCTCAGTTCACCAGTGCTGGATCCAGGTTCAAATGACAGGGAC TTGGGTTTTTACAACAGCGTGGCAAGTGGTCTGTCTCCTGGGCAGCCATATCCCAGACCC ACTGGGTTGAAAGTTCTGTGGGGTGGAGGGACCCCAAGGTGTTCCAAGCCAGTGGCTGCA CTGGCAGCAGGCCTCTGATAGGGAGGCGGGAAGGGTAAGCGCGGAGAGCAAGCTCCATTC TGGGTCGAGTGGAGGACTGGCTCCCAGGGTGAGTTCACACCAGTGCTCCCAGCTGGCGGC TGCTCAGTCTCTCCTGCTGGGCGAGCGCGGGGGGCCGGAGCCTATGCCATGCTGCTGGTG GAGCAAGAGGTGCCCTGGGAGCTCCCGATGCTGGAGGTGGCGCTGCTGCTCTCCGAGAAG GCCGGTGCAGGCACCCGCCCCACGGCTTCCGCTTGCTGAGGGAACCGTGCGCGCATATAG TCCCCATGCCACATGATCAGGCCCCGATGAGGATGCCCCTAGTGATGCCCACACGCGGGC AGTCAGGCCTTTCTGGGAACAAAAGATAGGTTGTGAGTTTACCCATAAACCCTCCGGCCC TCGGT |
| Restriction Sites | NotI-NotI |
| ACCN | NM_001114753 |
| Insert Size | 3000 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_001114753.1, NP_001108225.1 |
| RefSeq Size | 3077 bp |
| RefSeq ORF | 1977 bp |
| Locus ID | 2022 |
| UniProt ID | P17813 |
| Protein Families | Druggable Genome, ES Cell Differentiation/IPS, Transmembrane |
| Gene Summary | This gene encodes a homodimeric transmembrane protein which is a major glycoprotein of the vascular endothelium. This protein is a component of the transforming growth factor beta receptor complex and it binds to the beta1 and beta3 peptides with high affinity. Mutations in this gene cause hereditary hemorrhagic telangiectasia, also known as Osler-Rendu-Weber syndrome 1, an autosomal dominant multisystemic vascular dysplasia. This gene may also be involved in preeclampsia and several types of cancer. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2013] Transcript Variant: This variant (1) encodes the longer isoform (1, also known as L-endoglin). |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC226069 | ENG (Myc-DDK-tagged)-Human endoglin (ENG), transcript variant 1 |
CNY 7,344.00 |
|
| RC226069L1 | Lenti ORF clone of Human endoglin (ENG), transcript variant 1, Myc-DDK-tagged |
CNY 9,744.00 |
|
| RC226069L2 | Lenti ORF clone of Human endoglin (ENG), transcript variant 1, mGFP tagged |
CNY 6,460.00 |
|
| RC226069L3 | Lenti ORF clone of Human endoglin (ENG), transcript variant 1, Myc-DDK-tagged |
CNY 6,460.00 |
|
| RC226069L4 | Lenti ORF clone of Human endoglin (ENG), transcript variant 1, mGFP tagged |
CNY 9,744.00 |
|
| RG226069 | ENG (tGFP-tagged) - Human endoglin (ENG), transcript variant 1 |
CNY 8,944.00 |
