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Trpv6 (NM_022413) Mouse Tagged ORF Clone Lentiviral Particle
CAT＃: MR210315L3V
- LentiORF®
-
Lenti ORF particles, Trpv6 (Myc-DDK-tagged) - Mouse transient receptor potential cation channel, subfamily V, member 6 (Trpv6), 200ul, >10^7 TU/mL
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CNY 12,065.00
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规格
| Cited in 1 publication. |
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经常一起买 (2)
Specifications
| Product Data | |
| Product Name | Trpv6 (NM_022413) Mouse Tagged ORF Clone Lentiviral Particle |
| Synonyms | Cac; CAT; CaT1; Ecac2; Otrpc3 |
| Vector | pLenti-C-Myc-DDK-P2A-Puro |
| ACCN | NM_022413 |
| ORF Size | 2184 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(MR210315).
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| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_022413.2 |
| RefSeq Size | 2946 bp |
| RefSeq ORF | 2304 bp |
| Locus ID | 64177 |
| Gene Summary | Calcium selective cation channel that mediates Ca(2+) uptake in various tissues, including the intestine (PubMed:12765696, PubMed:12601087, PubMed:12574114, PubMed:14736889, PubMed:15123711, PubMed:17129178). Important for normal Ca(2+) ion homeostasis in the body, including bone and skin (PubMed:17129178, PubMed:22878123). The channel is activated by low internal calcium level, probably including intracellular calcium store depletion, and the current exhibits an inward rectification. Inactivation includes both a rapid Ca(2+)-dependent and a slower Ca(2+)-calmodulin-dependent mechanism; the latter may be regulated by phosphorylation (PubMed:15123711). In vitro, is slowly inhibited by Mg(2+) in a voltage-independent manner (PubMed:12601087). Heteromeric assembly with TRPV5 seems to modify channel properties. TRPV5-TRPV6 heteromultimeric concatemers exhibit voltage-dependent gating (PubMed:12574114).[UniProtKB/Swiss-Prot Function] |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
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Transient receptor potential vanilloid 5 (TRPV5), a highly Ca2+ -selective TRP channel in the rat brain: relevance to neuroendocrine regulation.
,null,
Journal of neuroendocrinology
,PubMed ID 28235149
[Trpv6]
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