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PLOD2 (NM_182943) Human Tagged ORF Clone Lentiviral Particle
CAT＃: RC207610L2V
- LentiORF®
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Lenti ORF particles, PLOD2 (mGFP-tagged) - Human procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 (PLOD2), transcript variant 1, 200ul, >10^7 TU/mL
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CNY 9,975.00
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Specifications
| Product Data | |
| Product Name | PLOD2 (NM_182943) Human Tagged ORF Clone Lentiviral Particle |
| Synonyms | BRKS2; LH2; TLH |
| Vector | pLenti-C-mGFP |
| ACCN | NM_182943 |
| ORF Size | 2274 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(RC207610).
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| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_182943.2 |
| RefSeq Size | 4072 bp |
| RefSeq ORF | 2277 bp |
| Locus ID | 5352 |
| Protein Pathways | Lysine degradation |
| MW | 87.1 kDa |
| Gene Summary | The protein encoded by this gene is a membrane-bound homodimeric enzyme that is localized to the cisternae of the rough endoplasmic reticulum. The enzyme (cofactors iron and ascorbate) catalyzes the hydroxylation of lysyl residues in collagen-like peptides. The resultant hydroxylysyl groups are attachment sites for carbohydrates in collagen and thus are critical for the stability of intermolecular crosslinks. Some patients with Ehlers-Danlos syndrome type VIB have deficiencies in lysyl hydroxylase activity. Mutations in the coding region of this gene are associated with Bruck syndrome. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008] |
Documents
| Product Manuals |
| FAQs |
| SDS |
