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NODAL (NM_018055) Human Tagged ORF Clone Lentiviral Particle
CAT＃: RC211302L4V
- LentiORF®
-
Lenti ORF particles, NODAL (mGFP-tagged) - Human nodal homolog (mouse) (NODAL), 200ul, >10^7 TU/mL
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CNY 9,975.00
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Specifications
| Product Data | |
| Product Name | NODAL (NM_018055) Human Tagged ORF Clone Lentiviral Particle |
| Synonyms | HTX5 |
| Vector | pLenti-C-mGFP-P2A-Puro |
| ACCN | NM_018055 |
| ORF Size | 1041 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(RC211302).
|
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_018055.3, NP_060525.2 |
| RefSeq Size | 2086 bp |
| RefSeq ORF | 1044 bp |
| Locus ID | 4838 |
| Protein Families | Cancer stem cells, Druggable Genome, Embryonic stem cells, ES Cell Differentiation/IPS, Induced pluripotent stem cells, Secreted Protein, Stem cell relevant signaling - TGFb/BMP signaling pathway |
| Protein Pathways | TGF-beta signaling pathway |
| MW | 39.6 kDa |
| Gene Summary | This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate the mature protein, which regulates early embryonic development. This protein is required for maintenance of human embryonic stem cell pluripotency and may play a role in human placental development. Mutations in this gene are associated with heterotaxy, a condition characterized by random orientation of visceral organs with respect to the left-right axis. [provided by RefSeq, Aug 2016] |
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