Mouse Abcb8 activation kit by CRISPRa

CAT#: GA209959

Abcb8 CRISPRa kit - CRISPR gene activation of mouse ATP-binding cassette, sub-family B (MDR/TAP), member 8



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CNY 12,255.00


货期*
4周

规格
    • 1 kit

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Specifications

Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol Abcb8
Locus ID 74610
Kit Components

GA209959G1, Abcb8 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA209959G2, Abcb8 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA209959G3, Abcb8 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_029020
Synonyms 4833412N02Rik; AA409895
Summary ATP-binding subunit of the mitochondrial potassium channel located in the mitochondrial inner membrane (By similarity). Together with CCDC51/MITOK, forms a protein complex localized in the mitochondria that mediates ATP-dependent potassium currents across the inner membrane (that is, mitoK(ATP) channel) (By similarity). Plays a role in mitochondrial iron transport (PubMed:22375032). Required for maintenance of normal cardiac function, possibly by influencing mitochondrial iron export and regulating the maturation of cytosolic iron sulfur cluster-containing enzymes (PubMed:22375032).[UniProtKB/Swiss-Prot Function]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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